Pluripotent stem cell‐derived retinal organoids for disease modeling and development of therapies

Retinal diseases constitute a genetically and phenotypically diverse group of clinical conditions leading to vision impairment or blindness with limited treatment options. Advances in reprogramming of somatic cells to induced pluripotent stem cells and generation of three‐dimensional organoids resem...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Jg. 38; H. 10; S. 1206 - 1215
Hauptverfasser:	Kruczek, Kamil, Swaroop, Anand
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Hoboken, USA John Wiley & Sons, Inc 01.10.2020 Oxford University Press
Schlagworte:	Animals Blindness Cell Differentiation Concise Review Drug therapy Electrophysiology Genetic Therapy Humans Models, Biological neural differentiation Neurodegeneration Organoids Organoids - pathology Pluripotency Pluripotent Stem Cells - cytology Regenerative Medicine Retina Retina - pathology Retinal cells retinal photoreceptors Somatic cells somatic stem cells Stem cells retinal photoreceptors neural differentiation somatic stem cells retina
ISSN:	1066-5099, 1549-4918, 1549-4918
Online-Zugang:	Volltext
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