Relevance of time‐dependence for clinically viable diffusion imaging of the spinal cord

Purpose Time‐dependence is a key feature of the diffusion‐weighted (DW) signal, knowledge of which informs biophysical modelling. Here, we study time‐dependence in the human spinal cord, as its axonal structure is specific and different from the brain. Methods We run Monte Carlo simulations using a...

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Bibliographic Details
Published in:	Magnetic resonance in medicine Vol. 81; no. 2; pp. 1247 - 1264
Main Authors:	Grussu, Francesco, Ianuş, Andrada, Tur, Carmen, Prados, Ferran, Schneider, Torben, Kaden, Enrico, Ourselin, Sébastien, Drobnjak, Ivana, Zhang, Hui, Alexander, Daniel C., Gandini Wheeler‐Kingshott, Claudia A. M.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.02.2019 John Wiley and Sons Inc
Subjects:	Adult Algorithms Axons Axons - pathology Brain Brain - diagnostic imaging Computer Simulation Cylinders Diffusion Diffusion Magnetic Resonance Imaging diffusion time Feasibility studies Female Full Papers—Biophysics and Basic Biomedical Research Healthy Volunteers Humans Image Processing, Computer-Assisted - methods Kurtosis Magnetic resonance imaging Male microstructure Monte Carlo Method Monte Carlo simulation Monte Carlo simulations Neuroimaging Spinal cord Spinal Cord - diagnostic imaging Substantia alba Time dependence Time Factors white matter white matter Monte Carlo simulations microstructure diffusion time spinal cord
ISSN:	0740-3194, 1522-2594, 1522-2594
Online Access:	Get full text
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