Microfluidics-Based Nanobiosensors for Healthcare Monitoring

Efficient healthcare management demands prompt decision-making based on fast diagnostics tools, astute data analysis, and informatics analysis. The rapid detection of analytes at the point of care is ensured using microfluidics in synergy with nanotechnology and biotechnology. The nanobiosensors use...

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Bibliographic Details
Published in:Molecular biotechnology Vol. 66; no. 3; pp. 378 - 401
Main Authors: Kumari, Monika, Gupta, Verruchi, Kumar, Natish, Arun, Ravi Kumar
Format: Journal Article
Language:English
Published: New York Springer US 01.03.2024
Springer Nature B.V
Subjects:
biochemical compounds
Biochemistry
Biological Techniques
Biomolecules
Biosensing Techniques - methods
Biotechnology
Cell Biology
chemical species
Chemistry
Chemistry and Materials Science
Data analysis
Decision analysis
Decision making
Diagnosis
diagnostic techniques
disease diagnosis
Health care
Human Genetics
Informatics
microfluidic technology
Microfluidics
Monitoring
Nanotechnology
Nanotechnology - methods
Optical communication
point-of-care testing
Protein Science
rapid methods
Review Paper
Telemedicine
Lab-on-a-chip
Biomedical diagnosis
Microfluidics
Nanobiosensors
ISSN:1073-6085, 1559-0305, 1559-0305
Online Access:Get full text
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Summary:Efficient healthcare management demands prompt decision-making based on fast diagnostics tools, astute data analysis, and informatics analysis. The rapid detection of analytes at the point of care is ensured using microfluidics in synergy with nanotechnology and biotechnology. The nanobiosensors use nanotechnology for testing, rapid disease diagnosis, monitoring, and management. In essence, nanobiosensors detect biomolecules through bioreceptors by modulating the physicochemical signals generating an optical and electrical signal as an outcome of the binding of a biomolecule with the help of a transducer. The nanobiosensors are sensitive and selective and play a significant role in the early identification of diseases. This article reviews the detection method used with the microfluidics platform for nanobiosensors and illustrates the benefits of combining microfluidics and nanobiosensing techniques by various examples. The fundamental aspects, and their application are discussed to illustrate the advancement in the development of microfluidics-based nanobiosensors and the current trends of these nano-sized sensors for point-of-care diagnosis of various diseases and their function in healthcare monitoring.
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ISSN:1073-6085
1559-0305
1559-0305
DOI:10.1007/s12033-023-00760-9