mRNAsi-related metabolic risk score model identifies poor prognosis, immunoevasive contexture, and low chemotherapy response in colorectal cancer patients through machine learning

Colorectal cancer (CRC) is one of the most fatal cancers of the digestive system. Although cancer stem cells and metabolic reprogramming have an important effect on tumor progression and drug resistance, their combined effect on CRC prognosis remains unclear. Therefore, we generated a 21-gene mRNA s...

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Veröffentlicht in:	Frontiers in immunology Jg. 13; S. 950782
Hauptverfasser:	Weng, Meilin, Li, Ting, Zhao, Jing, Guo, Miaomiao, Zhao, Wenling, Gu, Wenchao, Sun, Caihong, Yue, Ying, Zhong, Ziwen, Nan, Ke, Liao, Qingwu, Sun, Minli, Zhou, Di, Miao, Changhong
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Frontiers Media S.A 23.08.2022
Schlagworte:	colorectal cancer Immunology immunotherapy metabolism mRNAsi risk score model stemness
ISSN:	1664-3224, 1664-3224
Online-Zugang:	Volltext
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