Neuroserpin, a crucial regulator for axogenesis, synaptic modelling and cell–cell interactions in the pathophysiology of neurological disease

Neuroserpin is an axonally secreted serpin that is involved in regulating plasminogen and its enzyme activators, such as tissue plasminogen activator (tPA). The protein has been increasingly shown to play key roles in neuronal development, plasticity, maturation and synaptic refinement. The proteina...

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Bibliographic Details
Published in:	Cellular and molecular life sciences : CMLS Vol. 79; no. 3; p. 172
Main Authors:	Godinez, Angela, Rajput, Rashi, Chitranshi, Nitin, Gupta, Veer, Basavarajappa, Devaraj, Sharma, Samridhi, You, Yuyi, Pushpitha, Kanishka, Dhiman, Kunal, Mirzaei, Mehdi, Graham, Stuart, Gupta, Vivek
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01.03.2022 Springer Nature B.V
Subjects:	Alzheimer's disease Axons - metabolism Biochemistry Biomedical and Life Sciences Biomedicine Cell Biology Cell Communication Cell interactions Cellular communication Developmental plasticity Encephalopathy Glaucoma Humans Inclusion bodies Life Sciences Mental disorders Mutation Neoplasms - metabolism Neoplasms - pathology Nervous System Diseases - metabolism Nervous System Diseases - pathology Neurodegenerative diseases Neurological diseases Neuronal Plasticity neurons Neuropeptides - chemistry Neuropeptides - metabolism Neuroserpin pathophysiology plasminogen Plasminogen - metabolism plasticity Polymers Proteinase Proteinase inhibitors Proteins Review Serpins - chemistry Serpins - metabolism Signal Transduction Signaling stroke Synaptic plasticity Synaptogenesis t-Plasminogen activator Therapeutic targets therapeutics Thrombolytic drugs Tissue Plasminogen Activator - metabolism Glaucoma Stroke Serpin Alzheimer’s disease Tissue plasminogen activator Retina Neuroserpin Plasminogen
ISSN:	1420-682X, 1420-9071, 1420-9071
Online Access:	Get full text
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