Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff

Staff working in units that were highly exposed to coronavirus disease 2019 were invited to participate in a 6-month study on the carriage and seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The results from visits on Day 1 and Day 15 show that 41 cases of SARS-CoV-2...

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Bibliographic Details
Published in:The Journal of hospital infection Vol. 106; no. 1; pp. 102 - 106
Main Authors: Martin, C., Montesinos, I., Dauby, N., Gilles, C., Dahma, H., Van Den Wijngaert, S., De Wit, S., Delforge, M., Clumeck, N., Vandenberg, O.
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01.09.2020
The Healthcare Infection Society. Published by Elsevier Ltd
Subjects:
Adult
Antibodies
Asymptomatic
Asymptomatic Diseases
Belgium
Betacoronavirus - immunology
Carriage
Coronavirus Infections - immunology
COVID-19
COVID-19 units
Diagnostic Tests, Routine - standards
Diagnostic Tests, Routine - statistics & numerical data
Female
Hospital staff
Humans
Male
Middle Aged
Pandemics
Personnel, Hospital - statistics & numerical data
Pneumonia, Viral - immunology
Reverse Transcriptase Polymerase Chain Reaction - standards
Reverse Transcriptase Polymerase Chain Reaction - statistics & numerical data
Risk Assessment
Risk Factors
SARS-CoV-2
Seroepidemiologic Studies
Belgium
Antibodies
Asymptomatic
COVID-19 units
Hospital staff
Carriage
ISSN:0195-6701, 1532-2939, 1532-2939
Online Access:Get full text
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Summary:Staff working in units that were highly exposed to coronavirus disease 2019 were invited to participate in a 6-month study on the carriage and seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The results from visits on Day 1 and Day 15 show that 41 cases of SARS-CoV-2 infection were confirmed by reverse transcriptase polymerase chain reaction and/or serology in 326 participants (overall infection rate 12.6%). The presence of comorbidities or symptoms at the time of sample collection was a risk factor for infection, but working as a physician/nurse was not a risk factor. Universal screening in high-risk units, irrespective of symptoms, allowed the identification of asymptomatic and potentially contagious infected workers, enabling them to self-isolate for 7 days.
Bibliography:ObjectType-Article-1
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ISSN:0195-6701
1532-2939
1532-2939
DOI:10.1016/j.jhin.2020.06.028