Original antigenic sin: A comprehensive review

The concept of “original antigenic sin” was first proposed by Thomas Francis, Jr. in 1960. This phenomenon has the potential to rewrite what we understand about how the immune system responds to infections and its mechanistic implications on how vaccines should be designed. Antigenic sin has been de...

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Vydáno v:	Journal of autoimmunity Ročník 83; s. 12 - 21
Hlavní autoři:	Vatti, Anup, Monsalve, Diana M., Pacheco, Yovana, Chang, Christopher, Anaya, Juan-Manuel, Gershwin, M. Eric
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Elsevier Ltd 01.09.2017
Témata:	Allergy and Immunology Animals Antibody-dependent enhancement Antigens - immunology Bocavirus Dengue Humans Immune Tolerance Immunity, Humoral Immunodominant Epitopes - immunology Immunologic Memory Infection - immunology Influenza Memory immune response Models, Immunological Vaccination Vaccines - immunology Zika virus Bocavirus Vaccination Dengue Influenza Zika virus Antibody-dependent enhancement Memory immune response
ISSN:	0896-8411, 1095-9157, 1095-9157
On-line přístup:	Získat plný text
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