Changes in treatment of community-onset Clostridioides difficile infection after release of updated guidelines, Atlanta, Georgia, 2018

Updated Clostridioides difficile infection (CDI) guidelines published in 2018 recommend vancomycin as first-line treatment. Of 833 community-onset CDI cases in metropolitan Atlanta, Georgia in 2018, over half did not receive first-line treatment, although guideline adherence increased over the year....

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Veröffentlicht in:Anaerobe Jg. 70; S. 102364
Hauptverfasser: Adelman, Max W., Goodenough, Dana, Sefton, Samantha, Mackey, Carolyn, Thomas, Stepy, Fridkin, Scott K., Woodworth, Michael H.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England Elsevier Ltd 01.08.2021
Schlagworte:
Adult
Aged
Anti-Bacterial Agents - standards
Anti-Bacterial Agents - therapeutic use
Clostridioides difficile - drug effects
Clostridioides difficile - physiology
Clostridioides difficile infection
Clostridium difficile
Clostridium Infections - drug therapy
Clostridium Infections - microbiology
Cohort Studies
Community-Acquired Infections - drug therapy
Community-Acquired Infections - microbiology
Female
Georgia
Guideline-adherent treatment
guidelines
Guidelines as Topic
Humans
Male
Metronidazole
Metronidazole - standards
Metronidazole - therapeutic use
Middle Aged
Vancomycin
Vancomycin - standards
Vancomycin - therapeutic use
Georgia
Clostridioides difficile infection
Metronidazole
Vancomycin
Guideline-adherent treatment
ISSN:1075-9964, 1095-8274, 1095-8274
Online-Zugang:Volltext
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Zusammenfassung:Updated Clostridioides difficile infection (CDI) guidelines published in 2018 recommend vancomycin as first-line treatment. Of 833 community-onset CDI cases in metropolitan Atlanta, Georgia in 2018, over half did not receive first-line treatment, although guideline adherence increased over the year. Second-line treatment was more common in patients treated in ambulatory settings. [Display omitted] •2018 Clostridioides difficile guidelines recommend treatment with vancomycin.•Use of vancomycin increased throughout the year after guideline publication.•Patients treated in an ambulatory setting were less likely to receive vancomycin.•These findings can help target education to improve guideline-adherent prescribing.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1075-9964
1095-8274
1095-8274
DOI:10.1016/j.anaerobe.2021.102364