Generation and gene expression profiling of 48 transcription-factor-inducible mouse embryonic stem cell lines

Mouse embryonic stem cells (ESCs) can differentiate into a wide range – and possibly all cell types in vitro , and thus provide an ideal platform to study systematically the action of transcription factors (TFs) in cell differentiation. Previously, we have generated and analyzed 137 TF-inducible mou...

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Veröffentlicht in:	Scientific reports Jg. 6; H. 1; S. 25667
Hauptverfasser:	Yamamizu, Kohei, Sharov, Alexei A., Piao, Yulan, Amano, Misa, Yu, Hong, Nishiyama, Akira, Dudekula, Dawood B., Schlessinger, David, Ko, Minoru S. H.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 06.05.2016 Nature Publishing Group
Schlagworte:	13 13/100 38/39 42 631/532/2117 631/553 631/80 64/60 Animals Biomarkers - metabolism Cell differentiation Cell Differentiation - genetics Cell Line Cell lines Doxycycline Embryo cells Gene expression Gene Expression Profiling Gene Expression Regulation Gene Ontology Humanities and Social Sciences Islet-1 protein Leukocytes Mice Mouse Embryonic Stem Cells - metabolism multidisciplinary Organ Specificity - genetics Phenotype Protein Binding - genetics Reproducibility of Results Science Science (multidisciplinary) Stem cell transplantation Stem cells Transcription factors Transcription Factors - metabolism Transcriptome - genetics
ISSN:	2045-2322, 2045-2322
Online-Zugang:	Volltext
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