Multiparameter flow cytometric analysis of CD4 and CD8 T cell subsets in young and old people

Background T cell-mediated immunity in elderly people is compromised in ways reflected in the composition of the peripheral T cell pool. The advent of polychromatic flow cytometry has made analysis of cell subsets feasible in unprecedented detail. Results Here we document shifts in subset distributi...

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Veröffentlicht in:	Immunity & ageing Jg. 5; H. 1; S. 6
Hauptverfasser:	Koch, Sven, Larbi, Anis, Derhovanessian, Evelyna, Özcelik, Dennis, Naumova, Elissaveta, Pawelec, Graham
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 25.07.2008 BioMed Central Ltd BMC
Schlagworte:	Aging Antibodies Biomedical and Life Sciences Biomedicine Clinical Nutrition Flow cytometry Geriatrics/Gerontology Health aspects Immune response Immunology Methods Physiological aspects Public Health T cells Bulgaria Netherlands Germany Altered Frequency Double Negative Cell TEMRA Cell Polychromatic Flow Cytometry Central Memory
ISSN:	1742-4933, 1742-4933
Online-Zugang:	Volltext
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