Critical role of activated protein C in early coagulopathy and later organ failure, infection and death in trauma patients

Recent studies have identified an acute traumatic coagulopathy that is present on admission to the hospital and is independent of iatrogenic causes. We have previously reported that this coagulopathy is due to the association of severe injury and shock and is characterized by a decrease in plasma pr...

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Bibliographic Details
Published in:	Annals of surgery Vol. 255; no. 2; p. 379
Main Authors:	Cohen, Mitchell Jay, Call, Mariah, Nelson, Mary, Calfee, Carolyn S, Esmon, Charles T, Brohi, Karim, Pittet, Jean Francois
Format:	Journal Article
Language:	English
Published:	United States 01.02.2012
Subjects:	Adult Blood Coagulation Disorders - blood Blood Coagulation Disorders - etiology Female Humans Linear Models Logistic Models Male Middle Aged Multiple Organ Failure - blood Multiple Organ Failure - etiology Pneumonia, Ventilator-Associated - blood Prognosis Prospective Studies Protein C - metabolism Wounds and Injuries - blood Wounds and Injuries - complications Wounds and Injuries - mortality
ISSN:	1528-1140, 1528-1140
Online Access:	Get more information
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