Flow Cytometry Characterization of Cerebrospinal Fluid Monocytes in Patients With Postoperative Cognitive Dysfunction: A Pilot Study

Animal models suggest postoperative cognitive dysfunction may be caused by brain monocyte influx. To study this in humans, we developed a flow cytometry panel to profile cerebrospinal fluid (CSF) samples collected before and after major noncardiac surgery in 5 patients ≥60 years of age who developed...

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Bibliographic Details

Published in:	Anesthesia and analgesia Vol. 129; no. 5; p. e150
Main Authors:	Berger, Miles, Murdoch, David M, Staats, Janet S, Chan, Cliburn, Thomas, Jake P, Garrigues, Grant E, Browndyke, Jeffrey N, Cooter, Mary, Quinones, Quintin J, Mathew, Joseph P, Weinhold, Kent J
Format:	Journal Article
Language:	English
Published:	United States 01.11.2019
Subjects:	Cerebrospinal Fluid - cytology Flow Cytometry - methods GPI-Linked Proteins - analysis Humans Lipopolysaccharide Receptors - analysis Monocytes - immunology Pilot Projects Postoperative Cognitive Complications - cerebrospinal fluid Postoperative Cognitive Complications - etiology Receptors, IgG - analysis
ISSN:	1526-7598, 1526-7598
Online Access:	Get more information
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