A review of keratoconus: Diagnosis, pathophysiology, and genetics
We discuss new approaches to the early detection of keratoconus and recent investigations regarding the nature of its pathophysiology. We review the current evidence for its complex genetics and evaluate the presently identified genes/loci and potential candidate gene/loci. In addition, we highlight...
Saved in:
| Published in: | Survey of ophthalmology Vol. 62; no. 6; pp. 770 - 783 |
|---|---|
| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
Elsevier Inc
01.11.2017
|
| Subjects: | |
| ISSN: | 0039-6257, 1879-3304, 1879-3304 |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | We discuss new approaches to the early detection of keratoconus and recent investigations regarding the nature of its pathophysiology. We review the current evidence for its complex genetics and evaluate the presently identified genes/loci and potential candidate gene/loci. In addition, we highlight current research methodologies that may be used to further elucidate the pathogenesis of keratoconus. |
|---|---|
| AbstractList | We discuss new approaches to the early detection of keratoconus and recent investigations regarding the nature of its pathophysiology. We review the current evidence for its complex genetics and evaluate the presently identified genes/loci and potential candidate gene/loci. In addition, we highlight current research methodologies that may be used to further elucidate the pathogenesis of keratoconus. We discuss new approaches to the early detection of keratoconus and recent investigations regarding the nature of its pathophysiology. We review the current evidence for its complex genetics and evaluate the presently identified genes/loci and potential candidate gene/loci. In addition, we highlight current research methodologies that may be used to further elucidate the pathogenesis of keratoconus.We discuss new approaches to the early detection of keratoconus and recent investigations regarding the nature of its pathophysiology. We review the current evidence for its complex genetics and evaluate the presently identified genes/loci and potential candidate gene/loci. In addition, we highlight current research methodologies that may be used to further elucidate the pathogenesis of keratoconus. |
| Author | Maycock, Nicholas Mas Tur, Veronica Jayaswal, Rakesh MacGregor, Cheryl O'Brart, David |
| Author_xml | – sequence: 1 givenname: Veronica surname: Mas Tur fullname: Mas Tur, Veronica organization: Eye Department, Queen Alexandra Hospital, Portsmouth, Hants, United Kingdom – sequence: 2 givenname: Cheryl surname: MacGregor fullname: MacGregor, Cheryl organization: Eye Department, Queen Alexandra Hospital, Portsmouth, Hants, United Kingdom – sequence: 3 givenname: Rakesh surname: Jayaswal fullname: Jayaswal, Rakesh organization: Eye Department, Queen Alexandra Hospital, Portsmouth, Hants, United Kingdom – sequence: 4 givenname: David surname: O'Brart fullname: O'Brart, David organization: Department of Ophthalmology, St Thomas' Hospital, London, United Kingdom – sequence: 5 givenname: Nicholas surname: Maycock fullname: Maycock, Nicholas email: nicholas.maycock@me.com organization: Department of Ophthalmology, St Thomas' Hospital, London, United Kingdom |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28688894$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkMtuGyEUQFGVqnHS_kI13XWRmVw8Mzy6qSz3FSlSN8kaYbhj44zBBSaV_75ETqsqK2-AxbkH3XNBznzwSMgHCg0Fyq63TZriY9hv8kaPzRwob4A1APIVmVHBZd220J2RGUArazbv-Tm5SGkLAF0r-RtyPhdMCCG7GVksqoiPDn9XYageMOocTPBT-lR9cXrtQ3LpqtrrvCm_HZILY1gfrirtbbVGj9mZ9Ja8HvSY8N3zfUnuv329W_6ob39-v1kubmvTA821Zb1hYGzHUApkeg7WDqK8BglcCtoLahllrWW87wzjbTkGIfkKV3qwZmgvycejdx_DrwlTVjuXDI6j9himpKiknLGeUSjo-2d0Wu3Qqn10Ox0P6u_aBZBHwMSQUsThH0JBPSVWW_VfYvWUWAFTJXGZ_fxi1rissws-R-3GkwzLowFLrtI-qmQceoPWRTRZ2eBOsixeWMzovDN6fMDDiY4_hR63ZQ |
| CitedBy_id | crossref_primary_10_3390_jcm11185252 crossref_primary_10_1136_bmjophth_2022_001225 crossref_primary_10_1080_02713683_2022_2058020 crossref_primary_10_1177_25158414221083362 crossref_primary_10_1038_s41598_019_55866_5 crossref_primary_10_1016_j_exer_2023_109488 crossref_primary_10_1080_13816810_2020_1799415 crossref_primary_10_3390_diagnostics14202280 crossref_primary_10_1002_ccr3_2725 crossref_primary_10_1038_s41598_021_84370_y crossref_primary_10_1007_s40123_022_00489_9 crossref_primary_10_1016_j_imed_2024_09_006 crossref_primary_10_1371_journal_pone_0297268 crossref_primary_10_3390_ijms23031255 crossref_primary_10_1111_aos_15654 crossref_primary_10_1016_j_jcjo_2021_09_006 crossref_primary_10_1097_ICO_0000000000002727 crossref_primary_10_1002_jbio_201960234 crossref_primary_10_3390_biomimetics9020073 crossref_primary_10_1080_02713683_2022_2081979 crossref_primary_10_2196_27363 crossref_primary_10_2147_OPTH_S450916 crossref_primary_10_3389_fcell_2023_1133680 crossref_primary_10_1038_s41598_021_02035_2 crossref_primary_10_3389_fped_2022_937246 crossref_primary_10_7717_peerj_8982 crossref_primary_10_1016_j_survophthal_2024_04_008 crossref_primary_10_1038_s41433_022_02242_9 crossref_primary_10_1097_ICO_0000000000002161 crossref_primary_10_2147_OPTH_S301330 crossref_primary_10_1016_j_clae_2021_101559 crossref_primary_10_1364_AO_56_009787 crossref_primary_10_3390_life13112223 crossref_primary_10_1007_s40123_023_00858_y crossref_primary_10_2147_OPTH_S443027 crossref_primary_10_3389_fgene_2023_1251951 crossref_primary_10_1111_aos_14433 crossref_primary_10_1097_MD_0000000000023769 crossref_primary_10_1007_s10792_021_02114_3 crossref_primary_10_1097_ICO_0000000000002733 crossref_primary_10_1167_iovs_66_11_30 crossref_primary_10_1038_s41598_021_93821_5 crossref_primary_10_1001_jamaophthalmol_2023_5176 crossref_primary_10_3928_1081597X_20210330_01 crossref_primary_10_1186_s40662_020_00225_z crossref_primary_10_1155_2020_6667507 crossref_primary_10_1097_ICO_0000000000002170 crossref_primary_10_1097_j_jcrs_0000000000000990 crossref_primary_10_3389_fmed_2022_944504 crossref_primary_10_1001_jamaophthalmol_2019_2058 crossref_primary_10_1007_s10792_022_02334_1 crossref_primary_10_1097_ICO_0000000000001896 crossref_primary_10_1016_j_exer_2024_109978 crossref_primary_10_1097_j_jcrs_0000000000001160 crossref_primary_10_1016_j_clae_2024_102321 crossref_primary_10_1097_CND_0000000000000320 crossref_primary_10_1177_11206721211070915 crossref_primary_10_1186_s12886_021_02066_3 crossref_primary_10_1038_s41598_020_77122_x crossref_primary_10_1039_D2BM00584K crossref_primary_10_1111_ceo_13136 crossref_primary_10_1111_cxo_12891 crossref_primary_10_1007_s00417_024_06682_9 crossref_primary_10_1038_s41598_024_59037_z crossref_primary_10_1016_j_ajo_2023_08_003 crossref_primary_10_1016_j_ajo_2023_08_004 crossref_primary_10_1016_j_mehy_2021_110699 crossref_primary_10_1155_2020_3493614 crossref_primary_10_3390_biomedicines10102348 crossref_primary_10_1177_1120672119887874 crossref_primary_10_1038_s41433_019_0554_4 crossref_primary_10_1093_hmg_ddab075 crossref_primary_10_1186_s40662_025_00449_x crossref_primary_10_1007_s10792_024_03049_1 crossref_primary_10_1186_s12886_024_03353_5 crossref_primary_10_7759_cureus_60277 crossref_primary_10_1097_ICO_0000000000001946 crossref_primary_10_7759_cureus_86668 crossref_primary_10_3390_ijerph192013341 crossref_primary_10_1038_s41598_024_63109_5 crossref_primary_10_1097_ICO_0000000000002352 crossref_primary_10_1111_all_14320 crossref_primary_10_1097_ICO_0000000000002475 crossref_primary_10_1016_j_ajo_2023_10_004 crossref_primary_10_1097_j_jcrs_0000000000001069 crossref_primary_10_1007_s10792_023_02751_w crossref_primary_10_1016_j_ajo_2019_08_014 crossref_primary_10_3389_fmed_2022_835843 crossref_primary_10_4103_IJO_IJO_595_23 crossref_primary_10_1016_j_optlaseng_2024_108124 crossref_primary_10_1016_j_ajo_2025_08_035 crossref_primary_10_1080_02713683_2019_1658787 crossref_primary_10_1016_j_jtos_2023_06_014 crossref_primary_10_2147_OPTH_S318317 crossref_primary_10_3389_fbioe_2022_812507 crossref_primary_10_3389_fmed_2021_724674 crossref_primary_10_4102_phcfm_v14i1_3668 crossref_primary_10_1097_ICO_0000000000002484 crossref_primary_10_2478_rrlm_2020_0018 crossref_primary_10_71110_ajo7910202517025391100 crossref_primary_10_4103_jmau_jmau_80_21 crossref_primary_10_1177_11206721221087551 crossref_primary_10_1117_1_JBO_28_9_095001 crossref_primary_10_3390_ijms231810796 crossref_primary_10_3889_oamjms_2022_8222 crossref_primary_10_1016_j_clae_2020_06_001 crossref_primary_10_1038_s41433_024_02994_6 crossref_primary_10_3390_medicina59091660 crossref_primary_10_1007_s00417_023_06059_4 crossref_primary_10_3390_metabo13020187 crossref_primary_10_1080_13816810_2021_1897849 crossref_primary_10_3389_fbioe_2021_596154 crossref_primary_10_1167_tvst_14_5_20 crossref_primary_10_4102_aveh_v83i1_832 crossref_primary_10_1007_s10792_021_02074_8 crossref_primary_10_1111_jcmm_70079 crossref_primary_10_1097_ICO_0000000000002130 crossref_primary_10_1111_aos_14509 crossref_primary_10_37039_1982_8551_20250036 crossref_primary_10_1097_ICO_0000000000003467 crossref_primary_10_1007_s10792_021_01739_8 crossref_primary_10_1007_s10528_023_10398_6 crossref_primary_10_1167_iovs_63_5_12 crossref_primary_10_1016_j_exer_2025_110260 crossref_primary_10_1038_s41598_020_62825_y crossref_primary_10_1155_2022_4740141 crossref_primary_10_1007_s10654_024_01128_2 crossref_primary_10_1038_s41598_024_57596_9 crossref_primary_10_1097_ACI_0000000000000765 crossref_primary_10_1111_ceo_13958 crossref_primary_10_1038_s41598_021_00649_0 crossref_primary_10_1097_ICL_0000000000000652 crossref_primary_10_3928_1081597X_20230301_01 crossref_primary_10_1155_2020_1468258 crossref_primary_10_1016_j_xops_2025_100904 crossref_primary_10_1016_j_ajo_2023_11_009 crossref_primary_10_1080_08164622_2021_2012429 crossref_primary_10_1080_08164622_2022_2033602 crossref_primary_10_1097_ICO_0000000000003119 crossref_primary_10_1080_02713683_2019_1629597 crossref_primary_10_1097_ICO_0000000000002144 crossref_primary_10_1371_journal_pone_0239939 crossref_primary_10_1097_ICL_0000000000001053 crossref_primary_10_1097_j_jcrs_0000000000000669 crossref_primary_10_1136_bjophthalmol_2021_318804 crossref_primary_10_2147_OPTH_S325666 crossref_primary_10_1097_ICL_0000000000000641 crossref_primary_10_3928_1081597X_20220711_01 crossref_primary_10_1177_11206721231162441 crossref_primary_10_1167_iovs_18_24656 crossref_primary_10_1007_s10792_025_03617_z crossref_primary_10_2147_IJGM_S421298 crossref_primary_10_1016_j_actbio_2022_05_040 crossref_primary_10_1016_j_exer_2020_108398 crossref_primary_10_1007_s10561_024_10148_x crossref_primary_10_1097_ICO_0000000000002438 crossref_primary_10_1080_02713683_2021_1904510 crossref_primary_10_1016_j_jtos_2021_03_010 crossref_primary_10_1055_a_2206_1420 crossref_primary_10_1080_02713683_2021_2018466 crossref_primary_10_3390_ijms19051407 crossref_primary_10_1038_s41598_023_37472_8 crossref_primary_10_1109_ACCESS_2020_3016060 crossref_primary_10_1038_s42003_020_1037_7 crossref_primary_10_1080_13816810_2024_2427295 crossref_primary_10_1080_17469899_2024_2368801 crossref_primary_10_1371_journal_pone_0284454 crossref_primary_10_1016_j_ijengsci_2022_103701 crossref_primary_10_1155_2020_7505016 crossref_primary_10_1097_ICL_0000000000001169 crossref_primary_10_1177_1120672120972632 crossref_primary_10_1111_ceo_14047 crossref_primary_10_1016_j_survophthal_2021_08_004 crossref_primary_10_3389_fmed_2021_770138 crossref_primary_10_1007_s00347_021_01537_8 crossref_primary_10_1186_s12886_021_02128_6 crossref_primary_10_4103_joco_joco_189_22 crossref_primary_10_1016_j_ajo_2020_09_031 crossref_primary_10_3390_jcm12247620 crossref_primary_10_1016_j_clae_2020_05_002 crossref_primary_10_1016_j_clae_2021_03_001 crossref_primary_10_2147_OPTH_S439739 crossref_primary_10_1097_MD_0000000000029351 crossref_primary_10_1080_02713683_2022_2025846 crossref_primary_10_1155_2019_1748579 crossref_primary_10_4103_meajo_meajo_105_23 crossref_primary_10_2147_OPTH_S252940 crossref_primary_10_3390_bioengineering10040479 crossref_primary_10_3390_pharmaceutics14040799 crossref_primary_10_1097_ICL_0000000000000983 crossref_primary_10_1097_ICO_0000000000003669 crossref_primary_10_3928_1081597X_20210315_03 crossref_primary_10_1016_j_jtos_2019_01_008 crossref_primary_10_1055_a_2040_8283 crossref_primary_10_3928_1081597X_20230523_02 crossref_primary_10_12998_wjcc_v7_i19_3012 crossref_primary_10_1111_opo_13066 crossref_primary_10_1038_s41598_019_51502_4 crossref_primary_10_1089_omi_2019_0190 crossref_primary_10_1167_iovs_65_5_29 crossref_primary_10_1136_bjo_2022_322180 crossref_primary_10_3390_cells8101239 crossref_primary_10_1016_j_compbiomed_2024_108607 crossref_primary_10_3389_fmed_2025_1612452 crossref_primary_10_3928_1081597X_20210712_09 crossref_primary_10_1089_nat_2019_0838 crossref_primary_10_25122_jml_2022_0066 crossref_primary_10_1177_1120672121994731 crossref_primary_10_7759_cureus_16506 crossref_primary_10_1177_11206721211054730 crossref_primary_10_1186_s13104_020_05166_3 crossref_primary_10_1080_13816810_2021_1923034 crossref_primary_10_1080_13816810_2021_1923039 crossref_primary_10_3389_fbioe_2025_1595671 crossref_primary_10_1007_s40123_023_00795_w crossref_primary_10_1007_s00417_020_04929_9 crossref_primary_10_1016_j_clae_2024_102284 crossref_primary_10_4102_aveh_v83i1_905 crossref_primary_10_1097_ICU_0000000000000665 crossref_primary_10_1007_s00417_024_06664_x crossref_primary_10_3389_fbioe_2023_1273500 crossref_primary_10_1016_j_preteyeres_2019_100780 crossref_primary_10_1186_s12886_023_02976_4 crossref_primary_10_1186_s13023_020_01512_7 crossref_primary_10_1155_2022_5878460 crossref_primary_10_1097_ACI_0000000000000571 crossref_primary_10_1097_ICO_0000000000002632 crossref_primary_10_1080_09286586_2021_1892154 crossref_primary_10_1016_j_compbiomed_2019_04_024 crossref_primary_10_1167_iovs_64_7_12 crossref_primary_10_1097_ICO_0000000000002871 crossref_primary_10_1016_j_ajo_2022_12_016 crossref_primary_10_1016_j_ajo_2021_10_003 crossref_primary_10_3389_fmed_2023_1212314 crossref_primary_10_3390_sym13112132 crossref_primary_10_1007_s00347_021_01410_8 crossref_primary_10_1016_j_exer_2024_110207 crossref_primary_10_1016_j_clae_2025_102444 crossref_primary_10_1097_ICO_0000000000003176 crossref_primary_10_1007_s10792_024_03071_3 crossref_primary_10_1038_s41598_021_87291_y crossref_primary_10_1155_2024_6655217 crossref_primary_10_3389_fmats_2022_870134 crossref_primary_10_1109_ACCESS_2021_3086021 crossref_primary_10_1097_ICO_0000000000003609 crossref_primary_10_1097_ICL_0000000000000821 crossref_primary_10_3390_polym14194227 crossref_primary_10_1177_11206721221099257 crossref_primary_10_3390_ijerph17176049 crossref_primary_10_1038_s41598_021_84904_4 crossref_primary_10_1167_iovs_64_2_22 crossref_primary_10_1167_iovs_63_13_1 crossref_primary_10_3389_fmed_2023_1264061 crossref_primary_10_1177_11206721211039946 crossref_primary_10_4102_aveh_v82i1_780 crossref_primary_10_1097_ICU_0000000000000570 crossref_primary_10_1007_s10792_022_02491_3 crossref_primary_10_1038_s42003_021_01784_0 crossref_primary_10_1016_j_exer_2022_109342 crossref_primary_10_1097_ICO_0000000000003741 crossref_primary_10_1007_s00417_023_06093_2 crossref_primary_10_1016_j_aopr_2021_100005 crossref_primary_10_1038_s41572_024_00565_3 crossref_primary_10_3928_01913913_20210802_01 crossref_primary_10_1097_j_jcrs_0000000000000952 crossref_primary_10_1007_s10792_023_02715_0 crossref_primary_10_1097_ICL_0000000000001107 crossref_primary_10_3389_fgene_2022_988620 crossref_primary_10_1007_s00417_025_06825_6 crossref_primary_10_3928_1081597X_20230717_03 crossref_primary_10_1007_s10792_018_0965_4 crossref_primary_10_1186_s12886_021_02102_2 crossref_primary_10_3390_jcm11112960 crossref_primary_10_1167_iovs_65_6_22 crossref_primary_10_3928_1081597X_20220906_01 crossref_primary_10_1007_s00417_025_06792_y crossref_primary_10_3389_fgene_2020_00827 crossref_primary_10_1007_s00417_022_05749_9 crossref_primary_10_1016_j_clae_2023_101892 crossref_primary_10_1007_s10792_024_02992_3 crossref_primary_10_1007_s10792_022_02608_8 crossref_primary_10_1097_ICO_0000000000003072 crossref_primary_10_1111_opo_12956 crossref_primary_10_1186_s12882_021_02307_z crossref_primary_10_1016_j_yaoo_2021_04_019 crossref_primary_10_1080_13816810_2021_1992785 |
| Cites_doi | 10.1016/j.jcrs.2004.10.044 10.1016/j.exer.2010.06.020 10.1097/MOP.0b013e32834b20ec 10.1016/j.ophtha.2006.02.058 10.1167/iovs.04-1395 10.1080/13816810802008242 10.3109/02713683.2011.553306 10.1097/ICO.0b013e3181d007e1 10.1016/j.ajo.2016.12.015 10.1167/iovs.02-0671 10.3928/1081597X-20130318-07 10.1073/pnas.0306520101 10.1016/0039-6257(76)90066-7 10.1016/j.ajhg.2008.04.001 10.1167/iovs.04-0533 10.1016/j.ophtha.2004.11.050 10.1167/iovs.09-3689 10.1038/eye.1996.99 10.1167/iovs.12-10984 10.3109/13816810.2012.743569 10.1016/j.ophtha.2006.10.022 10.1016/S0014-4835(80)80027-3 10.1038/nrg3031 10.1167/iovs.04-0549 10.1167/iovs.06-0214 10.1016/j.jcrs.2007.04.021 10.3928/1081597X-20101006-01 10.1038/eye.2009.217 10.1167/iovs.05-1530 10.1093/hmg/11.9.1029 10.1038/eye.2013.278 10.1097/ICO.0b013e3181aebf7a 10.1016/j.jcrs.2010.10.046 10.1016/0039-6257(84)90094-8 10.1152/physiolgenomics.00140.2009 10.1016/S1367-0484(03)00022-5 10.1159/000328408 10.1097/ICO.0b013e31816a3591 10.1167/iovs.08-2173 10.1016/S0002-9394(00)00885-0 10.1038/eye.2000.154 10.3928/1081597X-20090610-06 10.1097/00003226-199101000-00002 10.1016/j.exer.2007.02.013 10.1016/S0002-9394(14)75135-9 10.1016/S0886-3350(99)00195-9 10.1167/iovs.11-7732 10.1006/exer.1999.0719 10.1167/iovs.13-11601 10.1038/eye.2014.333 10.1016/j.ajo.2013.07.018 10.1016/j.jprot.2013.05.023 10.1111/j.1442-9071.2009.02216.x 10.1097/ICO.0b013e3182821c1c 10.1001/archopht.1978.03910060051009 10.1167/iovs.04-1253 10.1007/s10384-007-0453-2 10.1136/bjo.2008.144253 10.1097/ICO.0b013e3182904950 10.1016/j.ophtha.2009.01.009 10.1016/j.jcrs.2009.11.012 10.1016/j.ajo.2013.03.034 10.1093/hmg/ddq333 10.1038/ng.2506 10.1186/1471-2164-11-715 10.1097/ICO.0000000000000408 10.1016/j.clae.2010.04.006 10.1074/jbc.M110.181099 10.1016/j.jcrs.2006.06.025 10.1167/iovs.11-8281 10.1097/00003226-198803000-00001 10.1159/000300309 10.1038/ejhg.2011.203 10.1016/S0002-9394(14)71239-5 10.1097/01.GIM.0000170772.41860.54 10.1177/002215540205000306 10.1097/00006324-195901000-00002 10.1167/iovs.05-1500 10.1016/j.jcrs.2009.03.050 10.1006/geno.1999.6093 10.1006/exer.2001.1157 10.1016/j.jcrs.2014.03.021 10.1111/j.1442-9071.2009.02009.x 10.1167/iovs.11-8261 10.1167/iovs.13-11781 10.1093/hmg/ddr460 10.1159/000308839 10.3928/1081597X-20090401-07 10.1016/j.ophtha.2003.07.006 10.1167/iovs.06-1177 10.1007/BF00407890 10.1038/362059a0 10.1056/NEJMoa1007064 10.1097/ICO.0b013e3181983a0c 10.1136/bjo.67.1.23 10.1016/j.ajhg.2011.09.014 10.1016/j.clae.2008.12.009 10.1007/s10038-008-0319-6 10.1016/S0161-6420(80)35145-2 10.1046/j.1475-1313.2002.00046.x 10.1016/S0039-6257(97)00119-7 10.1016/S0161-6420(03)00617-1 10.1016/j.ophtha.2009.07.002 10.1016/j.ophtha.2009.09.023 10.1006/geno.2000.6248 10.1167/iovs.08-2382 10.1097/ICO.0b013e31802c9e2e 10.1167/iovs.04-0694 10.1136/bjo.2008.142117 10.1111/cxo.12024 10.1016/j.cub.2004.02.027 10.1097/IIO.0b013e31820f1d2d 10.1056/NEJMra0905980 10.1097/ICO.0b013e31815a50e7 10.1159/000299577 10.1167/iovs.11-9268 10.1097/00003226-199403000-00003 10.1111/j.1442-9071.2008.01821.x 10.1093/hmg/4.3.485 |
| ContentType | Journal Article |
| Copyright | 2017 Elsevier Inc. Copyright © 2017 Elsevier Inc. All rights reserved. |
| Copyright_xml | – notice: 2017 Elsevier Inc. – notice: Copyright © 2017 Elsevier Inc. All rights reserved. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1016/j.survophthal.2017.06.009 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1879-3304 |
| EndPage | 783 |
| ExternalDocumentID | 28688894 10_1016_j_survophthal_2017_06_009 S0039625717300462 |
| Genre | Journal Article Review |
| GroupedDBID | --- --K --M .1- .55 .FO .GJ .~1 0R~ 123 1B1 1P~ 1RT 1~. 1~5 29Q 3O- 4.4 457 4G. 53G 5RE 5VS 7-5 71M 8P~ 9JM AAEDT AAEDW AAIKJ AAKOC AALRI AAOAW AAQFI AAQQT AAQXK AATTM AAXKI AAXUO AAYWO ABBQC ABJNI ABLJU ABMAC ABMZM ABOCM ABWVN ABXDB ACDAQ ACGFS ACIEU ACIUM ACLOT ACNCT ACRLP ACRPL ACVFH ADBBV ADCNI ADEZE ADMUD ADNMO AEBSH AEIPS AEKER AENEX AEUPX AEVXI AFFNX AFJKZ AFPUW AFRHN AFTJW AFXIZ AGHFR AGQPQ AGUBO AGYEJ AHHHB AIEXJ AIGII AIIUN AIKHN AITUG AJRQY AJUYK AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ ANKPU ANZVX APXCP ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CS3 DU5 EBS EFJIC EFKBS EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HEA HMK HMO HVGLF HZ~ IHE J1W K-O KOM L7B LZ2 M29 M41 MO0 N4W N9A O-L O9- OAUVE OF- OPF OQ~ OZT P-8 P-9 P2P PC. Q38 R2- ROL RPZ SAE SCC SDF SDG SDP SEL SES SPCBC SSH SSZ T5K UV1 WH7 WUQ X7M XPP Z5R ZGI ZXP ~G- ~HD AACTN AAIAV ABLVK ABYKQ AFCTW AFKWA AHPSJ AJBFU AJOXV AMFUW LCYCR RIG ZA5 9DU AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 |
| ID | FETCH-LOGICAL-c501t-d65c60cd46e98e6a20ddf88e6f907981581d6163d6754c6734c6f897bebafdcf3 |
| ISICitedReferencesCount | 315 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000413887500002&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0039-6257 1879-3304 |
| IngestDate | Sat Sep 27 17:59:02 EDT 2025 Wed Feb 19 02:41:34 EST 2025 Sat Nov 29 07:26:10 EST 2025 Tue Nov 18 21:41:08 EST 2025 Fri Feb 23 02:28:50 EST 2024 Tue Oct 14 19:30:48 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Keywords | review article keratoconus genetics |
| Language | English |
| License | Copyright © 2017 Elsevier Inc. All rights reserved. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c501t-d65c60cd46e98e6a20ddf88e6f907981581d6163d6754c6734c6f897bebafdcf3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 |
| PMID | 28688894 |
| PQID | 1917665610 |
| PQPubID | 23479 |
| PageCount | 14 |
| ParticipantIDs | proquest_miscellaneous_1917665610 pubmed_primary_28688894 crossref_primary_10_1016_j_survophthal_2017_06_009 crossref_citationtrail_10_1016_j_survophthal_2017_06_009 elsevier_sciencedirect_doi_10_1016_j_survophthal_2017_06_009 elsevier_clinicalkey_doi_10_1016_j_survophthal_2017_06_009 |
| PublicationCentury | 2000 |
| PublicationDate | November-December 2017 2017-11-00 2017 Nov - Dec 20171101 |
| PublicationDateYYYYMMDD | 2017-11-01 |
| PublicationDate_xml | – month: 11 year: 2017 text: November-December 2017 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Survey of ophthalmology |
| PublicationTitleAlternate | Surv Ophthalmol |
| PublicationYear | 2017 |
| Publisher | Elsevier Inc |
| Publisher_xml | – name: Elsevier Inc |
| References | Bykhovskaya, Li, Epifantseva (bib28) 2012; 7 Krumeich, Kezirian (bib70) 2009; 25 Kremer, Eagle, Rapuano (bib68) 1995; 119 Kenney, Brown (bib61) 2003; 26 Dash, Silvestri, Hughes (bib35) 2006; 12 Jahne (bib56) 1974; 68 Amsler (bib10) 1946; 111 Pathak, Nayak, Singh (bib107) 2011; 17 Paliwal, Singh, Tandon (bib104) 2009; 15 Mintz-Hittner, Semina, Frishman (bib95) 2004; 111 Alio, Pinero, Aleson (bib5) 2011; 37 Lively, Koehn, Hedberg-Buenz (bib83) 2010; 2 Zhou, Sawaguchi, Twining (bib153) 1998; 39 Wilson, Lin, Klyce (bib151) 1991; 10 Lema, Duran (bib74) 2005; 112 Noor, Mittal, Iqbal (bib101) 2002; 8 Li, Rabinowitz, Tang (bib80) 2006; 47 Feizi, Javadi, Kanavi (bib42) 2012; 7 Hom, Bruce (bib52) 2006 Nielsen K, Birkenkamp-Demtröder K, Ehlers N, et al. Identification of differentially expressed genes in keratoconus epithelium analyzed on microarrays. Invest Ophthalmol Vis Sci. 2003;44(6):2466–76. Lu, Vitart, Burdon (bib85) 2013; 45 Lee, Oum, Choi (bib73) 2009; 15 Kim, Rabinowitz, Meisler (bib65) 1999; 5 Burdon, Vincent (bib27) 2013; 2 Pinero, Alcon (bib110) 2014; 40 Droitcourt, Touboul, Ged (bib39) 2011; 4 Thalasselis, Etcheparaborda (bib141) 2002; 22 Ohtoshi, Wang, Maeda (bib102) 2004; 14 Paliwal, Tandon, Dube (bib105) 2011; 17 Cannon, Foster (bib29) 1978; 17 Luce (bib86) 2005; 31 Krachmer, Feder, Belin (bib67) 1984; 28 Liskova, Ebenezer, Hysi (bib82) 2007; 13 Wang, Jin, Zhang (bib148) 2013; 34 Abad, Rubinfeld, Del Valle (bib1) 2007; 114 Atilano, Coskun, Chwa (bib14) 2005; 46 Fontes, Ambrosio, Jardim (bib43) 2010; 117 Rosen, Siddique, Patterson (bib118) 1993; 362 Wheeler, Hauser, Afshari, Allingham, Liu (bib150) 2012 Smadja, Santhiago, Mello (bib130) 2013; 29 Katoh, Katoh (bib60) 2006; 17 Chaerkady, Shao, Scott (bib30) 2013; 87 Shah, Laiquzzaman (bib125) 2009; 32 Li, Bykhovskaya, Tang (bib79) 2013; 32 Bisceglia, Ciaschetti, De Bonis (bib21) 2005; 46 Tang, Picornell, Su (bib137) 2008; 27 Teer, Mullikin (bib140) 2010; 19 McGhee (bib92) 2009; 37 Karali, Peluso, Gennarino (bib58) 2010; 11 Bourges, Savoldelli, Dighiero (bib23) 2003; 110 Yanovitch, Li, Metlapally (bib152) 2009; 15 Krachmer (bib66) 1978; 96 Meek, Tuft, Huang (bib93) 2005; 46 Hofstetter (bib51) 1959; 36 Buddi, Lin, Atilano (bib25) 2002; 50 Abelson, Collin, Gillette (bib2) 1980; 90 Hammerstein (bib47) 1974; 190 Stabuc-Silih, Ravnik-Glavac, Glavac (bib132) 2009; 15 Li, Bykhovskaya, Haritunians (bib78) 2012; 21 Matthews, Cook, Majid (bib91) 2007; 84 Pinero, Alió, Alesón, Vergara, Miranda (bib111) 2010; 36 Udar, Atilano, Brown (bib144) 2006; 47 Suzuki, Amano, Honda (bib135) 2007; 51 Chow, Volgyi, Szilard (bib31) 2004; 101 Arce (bib12) 2010 Semina, Mintz-Hittner, Murray (bib124) 2000; 63 Smadja, Touboul, Cohen (bib131) 2013; 156 Belin, Duncan, Ambrosio (bib18) 2015; 4 Heon, Mathers, Alward (bib50) 1995; 4 Krivey, McCormick, Zaidman (bib69) 2001; 131 Sutton, Madigan, Roufas (bib134) 2010; 38 Veerappan, Pertile, Islam (bib147) 2010; 117 Reinstein, Archer, Gobbe (bib116) 2009; 25 Watson, Chow (bib149) 2011; 17 Duncan, Belin, Borgstrom (bib40) 2016; 11 Unal, Yucel, Akar (bib146) 2007; 26 Davidson, Hayes, Hardcastle (bib36) 2014; 28 Rabinowitz (bib114) 1998; 42 Lopes, Ramos, Faria-Correia (bib84) 2012; 1 Hong, Xu, Wei (bib53) 2013; 54 Abu, Frydman, Marek (bib3) 2008; 82 Ambrosio, Alonson, Luz (bib6) 2006; 32 Dash, George, O’Prey (bib34) 2010; 24 Aldave, Yellore, Salem (bib4) 2006; 47 Morshige, Wahlert, Kenney (bib98) 2007; 48 Li, Bykhovskaya, Canedo (bib77) 2013; 54 Burdon, Macgregor, Bykhovskaya (bib26) 2011; 52 Godefrooij, Ardine de Wit, Uiterwaal (bib45) 2017; 175 Gomes, Tan, Rapuano (bib46) 2015; 34 Baratz, Tosakulwong, Ryu (bib16) 2010; 11 Kenney, Chwa, Atilano (bib62) 2005; 46 Runager, Basaiawmoit, Deva (bib119) 2011; 286 Gajecka, Radhakrishna, Winters (bib44) 2009; 50 Lechner, Dash, Muszynska (bib72) 2013; 54 Maeda, Klyce, Smolek (bib87) 1994; 35 Nirankari, Karseh, Bastion (bib100) 1983; 67 Shah, Laiquzzaman, Bhoiwani (bib126) 2007; 48 Stabuc-Silih, Strazisar, Hawlina (bib133) 2010; 29 Hughes, Bradley, Campbell (bib55) 2011; 89 Takahashi, Nakayasu, Okisaka (bib136) 1990; 94 Tanwar, Kumar, Nayak (bib139) 2010; 16 Li, Yang, Rabinowitz (bib81) 2009; 35 Romero-Jimenez, Santodomingo-Rubido, Wolffsohn (bib117) 2010; 33 Kenney, Chwa, Opbroek (bib63) 1994; 13 Patel, Malta, Banitt (bib106) 2009; 93 Arnal, Peris-Martinez, Menezo (bib13) 2011; 52 Ortiz, Pinero, Shabayek (bib103) 2007; 33 Pramanik, Musch, Sutphin (bib113) 2006; 113 Mahmoud, Nunez, Blanco (bib88) 2013; 156 Schweitzer, Roberts, Mahmoud (bib123) 2010; 51 Daxer, Fratzl (bib37) 1997; 38 Polack (bib112) 1976; 20 Scarcelli, Pineda, Yun (bib122) 2012; 53 Pearson, Soneji, Sarvananthan (bib108) 2000; 14 Montalban, Alio, Javaloy (bib97) 2013; 32 Hayashi, Huang, Deeb (bib48) 2000; 67 Sharma, Tovey, Ghosh (bib128) 2010; 3 Karabatsas, Cook (bib57) 1996; 10 Tyynismaa, Sistonen, Tuupanen (bib143) 2002; 43 Bick, Dimmock (bib20) 2011; 23 Czugala, Karolak, Nowak (bib32) 2012; 20 Bisceglia, De Bonis, Pizzicoli (bib22) 2009; 50 Amsler (bib9) 1938; 96 Damaske (bib33) 1979; 178 Andreassen, Simonsen, Oxlund (bib11) 1980; 31 Karolak, Kulinska, Nowak (bib59) 2011; 17 Mannion, Tromans, O'Donnell (bib89) 2011; 36 Mok, Baek, Joo (bib96) 2008; 53 Sharma, Rodier, Tandon (bib127) 2012; 18 Ambrosio, Nogueira, Caldas (bib8) 2011; 51 Barsam, Petrushkin, Brennan (bib17) 2015; 29 Tang, Rabinowitz, Taylor (bib138) 2005; 7 Ambrosio, Belin (bib7) 2010; 26 Heon, Greenberg, Kopp (bib49) 2002; 11 Ryan, Oliveira-Fernandes, Lavker (bib120) 2006; 12 Sherwin, Brookes, Loh (bib129) 2002; 74 Belin, Khachikian (bib19) 2009; 37 Perry, Buxton, Fine (bib109) 1980; 87 Udar, Atilano, Small (bib145) 2009; 28 Rabinowitz, Rasheed (bib115) 1999; 25 Bron (bib24) 1988; 7 Mikami, Meguro, Teshigawara (bib94) 2013; 19 Lema, Duran, Ruiz (bib75) 2008; 27 Bamshad, Ng, Bigham (bib15) 2011; 12 Lam, Wiggs, Jurkunas (bib71) 2010; 29 Khachikian, Belin (bib64) 2009; 116 Eran, Almogit, David (bib41) 2008; 29 De Bonis, Laborante, Pizzicoli (bib38) 2011; 17 Saee-Rad, Hashemi, Miraftab (bib121) 2011; 17 Hosseini, Herd, Vincent (bib54) 2008; 14 Manolio (bib90) 2010; 2 Tourquetti, Ferrara (bib142) 2010; 1 Lema, Sobrino, Duran (bib76) 2009; 93 Ambrosio (10.1016/j.survophthal.2017.06.009_bib8) 2011; 51 Chaerkady (10.1016/j.survophthal.2017.06.009_bib30) 2013; 87 Kenney (10.1016/j.survophthal.2017.06.009_bib61) 2003; 26 Bisceglia (10.1016/j.survophthal.2017.06.009_bib22) 2009; 50 Hofstetter (10.1016/j.survophthal.2017.06.009_bib51) 1959; 36 Pathak (10.1016/j.survophthal.2017.06.009_bib107) 2011; 17 Kim (10.1016/j.survophthal.2017.06.009_bib65) 1999; 5 Noor (10.1016/j.survophthal.2017.06.009_bib101) 2002; 8 10.1016/j.survophthal.2017.06.009_bib99 Shah (10.1016/j.survophthal.2017.06.009_bib125) 2009; 32 Karabatsas (10.1016/j.survophthal.2017.06.009_bib57) 1996; 10 Pearson (10.1016/j.survophthal.2017.06.009_bib108) 2000; 14 Kenney (10.1016/j.survophthal.2017.06.009_bib62) 2005; 46 Duncan (10.1016/j.survophthal.2017.06.009_bib40) 2016; 11 De Bonis (10.1016/j.survophthal.2017.06.009_bib38) 2011; 17 Krachmer (10.1016/j.survophthal.2017.06.009_bib67) 1984; 28 Morshige (10.1016/j.survophthal.2017.06.009_bib98) 2007; 48 Takahashi (10.1016/j.survophthal.2017.06.009_bib136) 1990; 94 Lee (10.1016/j.survophthal.2017.06.009_bib73) 2009; 15 Mannion (10.1016/j.survophthal.2017.06.009_bib89) 2011; 36 Ryan (10.1016/j.survophthal.2017.06.009_bib120) 2006; 12 Montalban (10.1016/j.survophthal.2017.06.009_bib97) 2013; 32 Li (10.1016/j.survophthal.2017.06.009_bib80) 2006; 47 Abu (10.1016/j.survophthal.2017.06.009_bib3) 2008; 82 Heon (10.1016/j.survophthal.2017.06.009_bib50) 1995; 4 Watson (10.1016/j.survophthal.2017.06.009_bib149) 2011; 17 Davidson (10.1016/j.survophthal.2017.06.009_bib36) 2014; 28 Shah (10.1016/j.survophthal.2017.06.009_bib126) 2007; 48 Unal (10.1016/j.survophthal.2017.06.009_bib146) 2007; 26 Burdon (10.1016/j.survophthal.2017.06.009_bib27) 2013; 2 Li (10.1016/j.survophthal.2017.06.009_bib78) 2012; 21 Schweitzer (10.1016/j.survophthal.2017.06.009_bib123) 2010; 51 Amsler (10.1016/j.survophthal.2017.06.009_bib9) 1938; 96 Lam (10.1016/j.survophthal.2017.06.009_bib71) 2010; 29 Li (10.1016/j.survophthal.2017.06.009_bib81) 2009; 35 Burdon (10.1016/j.survophthal.2017.06.009_bib26) 2011; 52 Katoh (10.1016/j.survophthal.2017.06.009_bib60) 2006; 17 Lema (10.1016/j.survophthal.2017.06.009_bib74) 2005; 112 Godefrooij (10.1016/j.survophthal.2017.06.009_bib45) 2017; 175 Thalasselis (10.1016/j.survophthal.2017.06.009_bib141) 2002; 22 Wheeler (10.1016/j.survophthal.2017.06.009_bib150) 2012 Heon (10.1016/j.survophthal.2017.06.009_bib49) 2002; 11 Smadja (10.1016/j.survophthal.2017.06.009_bib131) 2013; 156 Mok (10.1016/j.survophthal.2017.06.009_bib96) 2008; 53 Udar (10.1016/j.survophthal.2017.06.009_bib144) 2006; 47 Saee-Rad (10.1016/j.survophthal.2017.06.009_bib121) 2011; 17 Patel (10.1016/j.survophthal.2017.06.009_bib106) 2009; 93 Perry (10.1016/j.survophthal.2017.06.009_bib109) 1980; 87 Li (10.1016/j.survophthal.2017.06.009_bib79) 2013; 32 Suzuki (10.1016/j.survophthal.2017.06.009_bib135) 2007; 51 Tang (10.1016/j.survophthal.2017.06.009_bib138) 2005; 7 Bron (10.1016/j.survophthal.2017.06.009_bib24) 1988; 7 Ortiz (10.1016/j.survophthal.2017.06.009_bib103) 2007; 33 Sharma (10.1016/j.survophthal.2017.06.009_bib128) 2010; 3 Maeda (10.1016/j.survophthal.2017.06.009_bib87) 1994; 35 Eran (10.1016/j.survophthal.2017.06.009_bib41) 2008; 29 Wilson (10.1016/j.survophthal.2017.06.009_bib151) 1991; 10 Jahne (10.1016/j.survophthal.2017.06.009_bib56) 1974; 68 Wang (10.1016/j.survophthal.2017.06.009_bib148) 2013; 34 Fontes (10.1016/j.survophthal.2017.06.009_bib43) 2010; 117 Lopes (10.1016/j.survophthal.2017.06.009_bib84) 2012; 1 Hughes (10.1016/j.survophthal.2017.06.009_bib55) 2011; 89 Arnal (10.1016/j.survophthal.2017.06.009_bib13) 2011; 52 Rosen (10.1016/j.survophthal.2017.06.009_bib118) 1993; 362 Hammerstein (10.1016/j.survophthal.2017.06.009_bib47) 1974; 190 Bykhovskaya (10.1016/j.survophthal.2017.06.009_bib28) 2012; 7 Dash (10.1016/j.survophthal.2017.06.009_bib35) 2006; 12 Krivey (10.1016/j.survophthal.2017.06.009_bib69) 2001; 131 Alio (10.1016/j.survophthal.2017.06.009_bib5) 2011; 37 Cannon (10.1016/j.survophthal.2017.06.009_bib29) 1978; 17 Matthews (10.1016/j.survophthal.2017.06.009_bib91) 2007; 84 Hom (10.1016/j.survophthal.2017.06.009_bib52) 2006 Li (10.1016/j.survophthal.2017.06.009_bib77) 2013; 54 Sherwin (10.1016/j.survophthal.2017.06.009_bib129) 2002; 74 Bick (10.1016/j.survophthal.2017.06.009_bib20) 2011; 23 Czugala (10.1016/j.survophthal.2017.06.009_bib32) 2012; 20 Daxer (10.1016/j.survophthal.2017.06.009_bib37) 1997; 38 Kenney (10.1016/j.survophthal.2017.06.009_bib63) 1994; 13 Tang (10.1016/j.survophthal.2017.06.009_bib137) 2008; 27 Semina (10.1016/j.survophthal.2017.06.009_bib124) 2000; 63 Rabinowitz (10.1016/j.survophthal.2017.06.009_bib115) 1999; 25 Sharma (10.1016/j.survophthal.2017.06.009_bib127) 2012; 18 Scarcelli (10.1016/j.survophthal.2017.06.009_bib122) 2012; 53 Liskova (10.1016/j.survophthal.2017.06.009_bib82) 2007; 13 Stabuc-Silih (10.1016/j.survophthal.2017.06.009_bib132) 2009; 15 Aldave (10.1016/j.survophthal.2017.06.009_bib4) 2006; 47 Abelson (10.1016/j.survophthal.2017.06.009_bib2) 1980; 90 Paliwal (10.1016/j.survophthal.2017.06.009_bib104) 2009; 15 Teer (10.1016/j.survophthal.2017.06.009_bib140) 2010; 19 Stabuc-Silih (10.1016/j.survophthal.2017.06.009_bib133) 2010; 29 Runager (10.1016/j.survophthal.2017.06.009_bib119) 2011; 286 Mintz-Hittner (10.1016/j.survophthal.2017.06.009_bib95) 2004; 111 Rabinowitz (10.1016/j.survophthal.2017.06.009_bib114) 1998; 42 Reinstein (10.1016/j.survophthal.2017.06.009_bib116) 2009; 25 Gomes (10.1016/j.survophthal.2017.06.009_bib46) 2015; 34 Droitcourt (10.1016/j.survophthal.2017.06.009_bib39) 2011; 4 Amsler (10.1016/j.survophthal.2017.06.009_bib10) 1946; 111 Lema (10.1016/j.survophthal.2017.06.009_bib76) 2009; 93 Ambrosio (10.1016/j.survophthal.2017.06.009_bib6) 2006; 32 Lu (10.1016/j.survophthal.2017.06.009_bib85) 2013; 45 Chow (10.1016/j.survophthal.2017.06.009_bib31) 2004; 101 Feizi (10.1016/j.survophthal.2017.06.009_bib42) 2012; 7 Paliwal (10.1016/j.survophthal.2017.06.009_bib105) 2011; 17 Belin (10.1016/j.survophthal.2017.06.009_bib19) 2009; 37 Pramanik (10.1016/j.survophthal.2017.06.009_bib113) 2006; 113 Andreassen (10.1016/j.survophthal.2017.06.009_bib11) 1980; 31 Manolio (10.1016/j.survophthal.2017.06.009_bib90) 2010; 2 Sutton (10.1016/j.survophthal.2017.06.009_bib134) 2010; 38 Buddi (10.1016/j.survophthal.2017.06.009_bib25) 2002; 50 Khachikian (10.1016/j.survophthal.2017.06.009_bib64) 2009; 116 Kremer (10.1016/j.survophthal.2017.06.009_bib68) 1995; 119 Nirankari (10.1016/j.survophthal.2017.06.009_bib100) 1983; 67 Udar (10.1016/j.survophthal.2017.06.009_bib145) 2009; 28 Lema (10.1016/j.survophthal.2017.06.009_bib75) 2008; 27 Damaske (10.1016/j.survophthal.2017.06.009_bib33) 1979; 178 Karali (10.1016/j.survophthal.2017.06.009_bib58) 2010; 11 Polack (10.1016/j.survophthal.2017.06.009_bib112) 1976; 20 Ohtoshi (10.1016/j.survophthal.2017.06.009_bib102) 2004; 14 Romero-Jimenez (10.1016/j.survophthal.2017.06.009_bib117) 2010; 33 Hosseini (10.1016/j.survophthal.2017.06.009_bib54) 2008; 14 Tourquetti (10.1016/j.survophthal.2017.06.009_bib142) 2010; 1 Zhou (10.1016/j.survophthal.2017.06.009_bib153) 1998; 39 Hong (10.1016/j.survophthal.2017.06.009_bib53) 2013; 54 Pinero (10.1016/j.survophthal.2017.06.009_bib111) 2010; 36 Tyynismaa (10.1016/j.survophthal.2017.06.009_bib143) 2002; 43 Pinero (10.1016/j.survophthal.2017.06.009_bib110) 2014; 40 Bourges (10.1016/j.survophthal.2017.06.009_bib23) 2003; 110 Mikami (10.1016/j.survophthal.2017.06.009_bib94) 2013; 19 Krumeich (10.1016/j.survophthal.2017.06.009_bib70) 2009; 25 Ambrosio (10.1016/j.survophthal.2017.06.009_bib7) 2010; 26 Karolak (10.1016/j.survophthal.2017.06.009_bib59) 2011; 17 Atilano (10.1016/j.survophthal.2017.06.009_bib14) 2005; 46 Abad (10.1016/j.survophthal.2017.06.009_bib1) 2007; 114 Belin (10.1016/j.survophthal.2017.06.009_bib18) 2015; 4 Tanwar (10.1016/j.survophthal.2017.06.009_bib139) 2010; 16 Veerappan (10.1016/j.survophthal.2017.06.009_bib147) 2010; 117 Hayashi (10.1016/j.survophthal.2017.06.009_bib48) 2000; 67 Gajecka (10.1016/j.survophthal.2017.06.009_bib44) 2009; 50 Luce (10.1016/j.survophthal.2017.06.009_bib86) 2005; 31 Smadja (10.1016/j.survophthal.2017.06.009_bib130) 2013; 29 Yanovitch (10.1016/j.survophthal.2017.06.009_bib152) 2009; 15 Bamshad (10.1016/j.survophthal.2017.06.009_bib15) 2011; 12 McGhee (10.1016/j.survophthal.2017.06.009_bib92) 2009; 37 Baratz (10.1016/j.survophthal.2017.06.009_bib16) 2010; 11 Bisceglia (10.1016/j.survophthal.2017.06.009_bib21) 2005; 46 Lively (10.1016/j.survophthal.2017.06.009_bib83) 2010; 2 Mahmoud (10.1016/j.survophthal.2017.06.009_bib88) 2013; 156 Lechner (10.1016/j.survophthal.2017.06.009_bib72) 2013; 54 Arce (10.1016/j.survophthal.2017.06.009_bib12) 2010 Barsam (10.1016/j.survophthal.2017.06.009_bib17) 2015; 29 Krachmer (10.1016/j.survophthal.2017.06.009_bib66) 1978; 96 Meek (10.1016/j.survophthal.2017.06.009_bib93) 2005; 46 Dash (10.1016/j.survophthal.2017.06.009_bib34) 2010; 24 |
| References_xml | – volume: 2 start-page: 281 year: 2010 end-page: 286 ident: bib83 article-title: Quantitative trait loci associated with murine central corneal thickness publication-title: Physiol Genomics – start-page: 503 year: 2006 end-page: 544 ident: bib52 article-title: Manual of contact lens prescribing and fitting – volume: 14 start-page: 625 year: 2000 end-page: 628 ident: bib108 article-title: Does ethnic influence the incidence or severity of keratoconus publication-title: Eye – volume: 38 start-page: 121 year: 1997 end-page: 129 ident: bib37 article-title: Collagen fibril orientation in the human corneal stroma and its implication in keratoconus publication-title: Invest Ophthalmol Vis Sci – volume: 12 start-page: 1175 year: 2006 end-page: 1184 ident: bib120 article-title: MicroRNAs of the mammalian eye display distinct and overlapping tissue specificity publication-title: Mol Vis – volume: 22 start-page: 330 year: 2002 end-page: 332 ident: bib141 article-title: Recurrent keratoconus 40 years after keratoplasty publication-title: Ophthalmic Physiol Opt – volume: 47 start-page: 3345 year: 2006 end-page: 3351 ident: bib144 article-title: SOD1: a candidate gene for keratoconus publication-title: Invest Ophthalmol Vis Sci – volume: 31 start-page: 435 year: 1980 end-page: 441 ident: bib11 article-title: Biomechanical properties of keratoconus and normal corneas publication-title: Exp Eye Res – volume: 54 start-page: 659 year: 2013 end-page: 665 ident: bib53 article-title: A new tonometer—the Corvis ST tonometer: clinical comparison with non-contact and Goldmann applanation tonometers publication-title: Invest Ophthalmol Vis Sci – volume: 51 start-page: 11 year: 2011 end-page: 38 ident: bib8 article-title: Evaluation of corneal shape and biomechanics before LASIK publication-title: Int Ophthalmol Clin – volume: 15 start-page: 2848 year: 2009 end-page: 2860 ident: bib132 article-title: Polymorphisms in publication-title: Mol Vis – volume: 46 start-page: 1948 year: 2005 end-page: 1956 ident: bib93 article-title: Changes in collagen orientation and distribution in keratoconus corneas publication-title: Invest Ophthalmol Vis Sci – volume: 29 start-page: 469 year: 2015 end-page: 474 ident: bib17 article-title: Acute corneal hydrops in keratoconus: a national prospective study of incidence and management publication-title: Eye – volume: 82 start-page: 1217 year: 2008 end-page: 1222 ident: bib3 article-title: Deleterious mutations in the publication-title: Am J Hum Genet – volume: 51 start-page: 265 year: 2007 end-page: 269 ident: bib135 article-title: Longitudinal changes in corneal irregular astigmatism and visual acuity in eyes with KCN publication-title: Jpn J Ophthalmol – volume: 24 start-page: 1085 year: 2010 end-page: 1092 ident: bib34 article-title: Mutational screening of VSX1 in keratoconus patients from the European population publication-title: Eye (Lond) – volume: 51 start-page: 2403 year: 2010 end-page: 2410 ident: bib123 article-title: Screening of forme fruste keratoconus with the ocular response analyzer publication-title: Invest Ophthalmol Vis Sci – volume: 17 start-page: 481 year: 2011 end-page: 485 ident: bib105 article-title: Familial segregation of a VSX1 mutation adds a new dimension to its role in the causation of keratoconus publication-title: Mol Vis – volume: 114 start-page: 1020 year: 2007 end-page: 1026 ident: bib1 article-title: Vertical D: a novel topographic pattern in some keratoconus suspects publication-title: Ophthalmology – volume: 12 start-page: 499 year: 2006 end-page: 505 ident: bib35 article-title: Fine mapping of the keratoconus with cataract locus on chromosome 15q and candidate gene analysis publication-title: Mol Vis – volume: 29 start-page: 274 year: 2013 end-page: 281 ident: bib130 article-title: Influence of the reference surface shape for discriminating between normal corneas, subclinical keratoconus and keratoconus publication-title: J Refract Surg – volume: 5 start-page: 475 year: 1999 end-page: 481 ident: bib65 article-title: Keratocyte apoptosis associated with keratoconus publication-title: Exp Eye Res – volume: 23 start-page: 594 year: 2011 end-page: 600 ident: bib20 article-title: Whole exome and whole genome sequencing publication-title: Curr Opin Pediatr – volume: 50 start-page: 1531 year: 2009 end-page: 1539 ident: bib44 article-title: Localization of a gene for keratoconus to a 5.6-Mb interval on 13q32 publication-title: Invest Ophthalmol Vis Sci – volume: 96 start-page: 1217 year: 1978 end-page: 1221 ident: bib66 article-title: Pellucid marginal corneal degeneration publication-title: Arch Ophthalmol – volume: 47 start-page: 3791 year: 2006 end-page: 3795 ident: bib80 article-title: Two-stage genome-wide linkage scan in keratoconus sib pair families publication-title: Invest Ophthalmol Vis Sci – volume: 19 start-page: R145 year: 2010 end-page: R151 ident: bib140 article-title: Exome sequencing: the sweet spot before whole genomes publication-title: Hum Mol Genet – volume: 101 start-page: 1754 year: 2004 end-page: 1759 ident: bib31 article-title: Control of late off-center cone bipolar cell differentiation and visual signaling by the homeobox gene Vsx1 publication-title: Proc Natl Acad Sci U S A – volume: 7 start-page: 4152 year: 2012 end-page: 4157 ident: bib28 article-title: Variation in the lysyl oxidase (LOX) gene is associated with keratoconus in family-based and case-control studies publication-title: Invest Ophthalmol Vis Sci – volume: 7 start-page: 328 year: 2012 end-page: 331 ident: bib42 article-title: Recurrent keratoconus in corneal graft after DALK procedure publication-title: J Ophthalmic Vis Res – volume: 43 start-page: 3160 year: 2002 end-page: 3164 ident: bib143 article-title: A locus for autosomal dominant keratoconus: linkage to 16q22.3-q23.1 in Finnish families publication-title: Invest Ophthalmol Vis Sci – volume: 25 start-page: 1327 year: 1999 end-page: 1335 ident: bib115 article-title: KISA% index: a quantitive videokeratography algorithm embodying minimal topographic criteria for diagnosis keratoconus publication-title: J Cataract Refract Surg – volume: 175 start-page: 169 year: 2017 end-page: 172 ident: bib45 article-title: Age-specific incidence and prevalence of keratoconus: a nationwide registration study publication-title: Am J Ophthalmol – volume: 36 start-page: 3 year: 1959 end-page: 11 ident: bib51 article-title: A keratoscopic survey of 13,395 eyes publication-title: Am J Optom Arch Am Acad Optom – reference: Nielsen K, Birkenkamp-Demtröder K, Ehlers N, et al. Identification of differentially expressed genes in keratoconus epithelium analyzed on microarrays. Invest Ophthalmol Vis Sci. 2003;44(6):2466–76. – volume: 39 start-page: 1117 year: 1998 end-page: 1124 ident: bib153 article-title: Expression of degradative enzymes and protease inhibitors in corneas with keratoconus publication-title: Invest Ophthalmol Vis Sci – volume: 4 start-page: 85 year: 2015 end-page: 93 ident: bib18 article-title: A new tomographic method of grading keratoconus: the ABCD Grading system publication-title: Int J Kerat Ect Cor Dis – volume: 36 start-page: 814 year: 2010 end-page: 825 ident: bib111 article-title: Corneal volume, pachymetry and correlation of anterior and posterior corneal shape in subclinical and different stages of clinical KCN publication-title: J Cataract Refract Surg – volume: 18 start-page: 2598 year: 2012 end-page: 2607 ident: bib127 article-title: Attenuation of corneal myofibroblast development through nanoparticle-mediated soluble transforming growth factor-beta type II receptor (sTGFbetaRII) gene transfer publication-title: Mol Vis – volume: 94 start-page: 1068 year: 1990 end-page: 1073 ident: bib136 article-title: Quantitative analysis of collagen fiberin keratoconus publication-title: Nihon Ganka Gakkai Zasshi – year: 2012 ident: bib150 article-title: The genetics of keratoconus: A review publication-title: Reprod Syst Sex Disord – volume: 84 start-page: 1125 year: 2007 end-page: 1134 ident: bib91 article-title: Changes in the balance of the tissue inhibitor of matrix metalloproteinases (TIMPs)-1 and -3 may promote keratocyte apoptosis in keratoconus publication-title: Exp Eye Res – volume: 25 start-page: 357 year: 2009 end-page: 365 ident: bib70 article-title: Circular keratotomy to reduce astigmatism and improve vision in stage I and II keratoconus publication-title: J Refract Surg – volume: 15 start-page: 2475 year: 2009 end-page: 2479 ident: bib104 article-title: A novel VSX1 mutation identified in an individual with keratoconus in India publication-title: Mol Vis – volume: 67 start-page: 128 year: 2000 end-page: 139 ident: bib48 article-title: RINX(VSX1), a novel homeobox gene expressed in the inner nuclear layer of the adult retina publication-title: Genomics – volume: 116 year: 2009 ident: bib64 article-title: Posterior elevation in keratoconus publication-title: Ophthalmology – volume: 14 start-page: 71 year: 2008 end-page: 80 ident: bib54 article-title: Genetic analysis of chromosome 20-related posterior polymorphous corneal dystrophy: genetic heterogeneity and exclusion of three candidate genes publication-title: Mol Vis – volume: 54 start-page: 3215 year: 2013 end-page: 3223 ident: bib72 article-title: Mutational spectrum of the publication-title: Invest Ophthalmol Vis Sci – volume: 48 start-page: 1087 year: 2007 end-page: 1094 ident: bib98 article-title: Second harmonic imaging microscopy of normal and keratoconus cornea publication-title: Invest Ophthalmol Vis Sci – volume: 28 start-page: 902 year: 2009 end-page: 907 ident: bib145 article-title: SOD1 haplotypes in familial keratoconus publication-title: Cornea – volume: 50 start-page: 341 year: 2002 end-page: 351 ident: bib25 article-title: Evidence of oxidative stress in human corneal diseases publication-title: J Histochem Cytochem – volume: 31 start-page: 156 year: 2005 end-page: 162 ident: bib86 article-title: Determining in vivo biomechanical properties of the cornea with an ocular response analyzer publication-title: J Cataract Refract Surg – volume: 286 start-page: 4951 year: 2011 end-page: 4958 ident: bib119 article-title: Human phenotypically distinct publication-title: J Biol Chem – volume: 46 start-page: 39 year: 2005 end-page: 45 ident: bib21 article-title: VSX1 mutational analysis in a series of Italian patients affected by keratoconus: detection of a novel mutation publication-title: Invest Ophthalmol Vis Sci – volume: 35 start-page: 2749 year: 1994 end-page: 2757 ident: bib87 article-title: Automated keratoconus screening with corneal topography analysis publication-title: Invest Ophthalmol Vis Sci – volume: 11 start-page: 3 year: 2016 end-page: 6 ident: bib40 article-title: Assessing progression of keratoconus: novel tomographic determinants publication-title: Eye Vis (Lond) – volume: 2 start-page: 166 year: 2010 end-page: 176 ident: bib90 article-title: Genome-wide association studies and assessment of the risk of disease publication-title: N Engl J Med – volume: 34 start-page: 359 year: 2015 end-page: 369 ident: bib46 article-title: Global consensus on keratoconus and ectatic disease publication-title: Cornea – volume: 33 start-page: 157 year: 2010 end-page: 166 ident: bib117 article-title: Keratoconus: a review publication-title: Cont Lens Anterior Eye – volume: 17 start-page: 1514 year: 2011 end-page: 1525 ident: bib107 article-title: Mitochondrial complex 1 gene analysis in keratoconus publication-title: Mol Vis – volume: 7 start-page: 163 year: 1988 end-page: 169 ident: bib24 article-title: Keratoconus publication-title: Cornea – volume: 178 start-page: 289 year: 1979 end-page: 296 ident: bib33 article-title: Value of therapeutic soft contact lenses in the treatment of recurrent corneal erosions publication-title: Ophthalmologica – volume: 1 start-page: 178 year: 2010 end-page: 181 ident: bib142 article-title: Corneal asphericity changes after implantation of intrastromal corneal ring segments in Keratoconus publication-title: J Emmetropia – volume: 17 start-page: 737 year: 2011 end-page: 744 ident: bib149 article-title: Absence of Vsx1 expression in the normal and damaged mouse cornea publication-title: Mol Vis – volume: 37 start-page: 552 year: 2011 end-page: 568 ident: bib5 article-title: Keratoconus-integrated characterization considering anterior corneal aberrations, internal astigmatism, and corneal biomechanics publication-title: J Cataract Refract Surg – volume: 27 start-page: 758 year: 2008 end-page: 763 ident: bib75 article-title: Inflammatory response to contact lenses in patients with keratoconus compared with myopic subjects publication-title: Cornea – volume: 10 start-page: 2 year: 1991 end-page: 8 ident: bib151 article-title: Corneal topography of keratoconus publication-title: Cornea – volume: 3 start-page: 440 year: 2010 end-page: 448 ident: bib128 article-title: AAV serotype influences gene transfer in corneal stroma publication-title: Exp Eye Res – volume: 38 start-page: 43 year: 2010 end-page: 48 ident: bib134 article-title: Secreted frizzled-related protein 1 (SFRP1) is highly upregulated in keratoconus epithelium: A novel finding highlighting a new potential focus for keratoconus research and treatment publication-title: Clin Exp Ophthalmol – volume: 17 start-page: 827 year: 2011 end-page: 843 ident: bib59 article-title: Sequence variants in COL4A1 and COL4A2 genes in Ecuadorian families with keratoconus publication-title: Mol Vis – volume: 53 start-page: 185 year: 2012 end-page: 190 ident: bib122 article-title: Brillouin optical microscopy for corneal biomechanics publication-title: Invest Ophthalmol Vis Sci – volume: 37 start-page: 160 year: 2009 end-page: 176 ident: bib92 article-title: 150 years of practical observations in the conical cornea – what have we learned? publication-title: Clin Exp Ophthalmol – volume: 34 start-page: 160 year: 2013 end-page: 166 ident: bib148 article-title: Common single nucleotide polymorphisms and keratoconus in the Han Chinese population publication-title: Ophthalmic Genet – volume: 90 start-page: 672 year: 1980 end-page: 678 ident: bib2 article-title: Recurrent keratoconus after keratoplasty publication-title: Am J Ophthalmol – volume: 12 start-page: 745 year: 2011 end-page: 755 ident: bib15 article-title: sequencing as a tool for Mendelian disease gene discovery publication-title: Nat Rev Genet – volume: 190 start-page: 293 year: 1974 end-page: 308 ident: bib47 article-title: Zur genetic des keratoconus publication-title: Albrecht Von Graefes Arch Klin Exp Ophthalmol – volume: 28 start-page: 293 year: 1984 end-page: 322 ident: bib67 article-title: Keratoconus and related non-inflammatory corneal thinning disorders publication-title: Surv Ophthalmol – volume: 112 start-page: 654 year: 2005 end-page: 659 ident: bib74 article-title: Inflammatory molecules in the tears of patients with keratoconus publication-title: Ophthalmology – volume: 50 start-page: 1081 year: 2009 end-page: 1086 ident: bib22 article-title: Linkage analysis in keratoconus: replication of locus 5q21.2 and identification of other suggestive Loci publication-title: Invest Ophthalmol Vis Sci – volume: 16 start-page: 2395 year: 2010 end-page: 2401 ident: bib139 article-title: VSX1 gene analysis in keratoconus publication-title: Mol Vis – volume: 27 start-page: 189 year: 2008 end-page: 192 ident: bib137 article-title: Three VSX1 gene mutations, L159M, R166W, and H244R, are not associated with keratoconus publication-title: Cornea – volume: 10 start-page: 451 year: 1996 end-page: 455 ident: bib57 article-title: Topographic analysis in pellucid marginal degeneration and keratoglobus publication-title: Eye (Lond) – volume: 117 start-page: 673 year: 2010 end-page: 679 ident: bib43 article-title: Corneal biomechanical metrics and anterior segment parameters in mild keratoconus publication-title: Ophthalmology – volume: 21 start-page: 421 year: 2012 end-page: 429 ident: bib78 article-title: A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries publication-title: Hum Mol Genet – volume: 87 start-page: 122 year: 2013 end-page: 131 ident: bib30 article-title: The keratoconus corneal proteome: loss of epithelial integrity and stromal degeneration publication-title: J Proteomics – volume: 2 start-page: 146 year: 2013 end-page: 154 ident: bib27 article-title: Insights into keratoconus from a genetic perspective publication-title: Clin Exp Optom – volume: 32 start-page: 1851 year: 2006 end-page: 1859 ident: bib6 article-title: Corneal-thickness spatial profile and corneal volume distribution: tomographic indices to detect keratoconus publication-title: J Cataract Refract Surg – volume: 13 start-page: 114 year: 1994 end-page: 124 ident: bib63 article-title: Increased gelatinolytic activity in keratoconus cultures. A correlation to an altered matrix metalloproteinase-2/tissue inhibitor of metalloproteinase ratio publication-title: Cornea – volume: 40 start-page: 870 year: 2014 end-page: 887 ident: bib110 article-title: In vivo characterization of corneal biomechanics publication-title: J Cataract Refract Surg – volume: 52 start-page: 8514 year: 2011 end-page: 8519 ident: bib26 article-title: Association of polymorphisms in the hepatocyte growth factor gene promoter with keratoconus publication-title: Invest Ophthalmol Vis Sci – volume: 4 start-page: 485 year: 1995 end-page: 488 ident: bib50 article-title: Linkage of posterior polymorphous corneal dystrophy to 20q11 publication-title: Hum Mol Genet – volume: 11 start-page: 1016 year: 2010 end-page: 1024 ident: bib16 article-title: E2-2 protein and Fuchs's corneal dystrophy publication-title: N Engl J Med – volume: 20 start-page: 389 year: 2012 end-page: 397 ident: bib32 article-title: Novel mutation and three other sequence variants segregating with phenotype at keratoconus 13q32 susceptibility locus publication-title: Eur J Hum Genet – volume: 35 start-page: 1597 year: 2009 end-page: 1603 ident: bib81 article-title: Keratoconus: Classification scheme based on videokeratography and clinical signs publication-title: J Cataract Refract Surg – volume: 53 start-page: 842 year: 2008 end-page: 849 ident: bib96 article-title: VSX1 gene variants are associated with keratoconus in unrelated Korean patients publication-title: J Hum Genet – volume: 17 start-page: 2482 year: 2011 end-page: 2494 ident: bib38 article-title: Mutational screening of VSX1, SPARC, SOD1, LOX, and TIMP3 in keratoconus publication-title: Mol Vis – volume: 13 start-page: 1887 year: 2007 end-page: 1891 ident: bib82 article-title: Molecular analysis of the VSX1 gene in familial keratoconus publication-title: Mol Vis – volume: 45 start-page: 155 year: 2013 end-page: 163 ident: bib85 article-title: Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus publication-title: Nat Genet – volume: 25 start-page: 604 year: 2009 end-page: 610 ident: bib116 article-title: Corneal epithelial thickness profile in the diagnosis of keratoconus publication-title: J Refract Surg – volume: 110 start-page: 1920 year: 2003 end-page: 1925 ident: bib23 article-title: Recurrence of keratoconus characteristics: a clinical and histological follow-up analysis of donor grafts publication-title: Ophthalmology – volume: 156 start-page: 237 year: 2013 end-page: 246.e1 ident: bib131 article-title: Detection of subclinical keratoconus using an automated decision tree classification publication-title: Am J Ophthalmol – volume: 8 start-page: 210 year: 2002 end-page: 215 ident: bib101 article-title: Superoxide dismutase–applications and relevance to human diseases publication-title: Med Sci Monit – volume: 119 start-page: 511 year: 1995 end-page: 512 ident: bib68 article-title: Histological evidence of recurrent keratoconus seven years after keratoplasty publication-title: Am J Ophthalmol – volume: 54 start-page: 2696 year: 2013 end-page: 2704 ident: bib77 article-title: Genetic association of publication-title: Invest Ophthalmol Vis Sci – volume: 15 start-page: 2480 year: 2009 end-page: 2487 ident: bib73 article-title: Evaluation of differentially expressed genes identified in keratoconus publication-title: Mol Vis – volume: 96 start-page: 77 year: 1938 end-page: 83 ident: bib9 article-title: Le keratocone fruste au javal publication-title: Ophthalmologica – volume: 26 start-page: 139 year: 2003 end-page: 146 ident: bib61 article-title: The cascade hypothesis of keratoconus publication-title: Cont Lens Anterior Eye – volume: 7 start-page: 397 year: 2005 end-page: 405 ident: bib138 article-title: Genomewide linkage scan in a multigeneration Caucasian pedigree identifies a novel locus for keratoconus on chromosome 5q14.3-q21.1 publication-title: Genet Med – volume: 4 start-page: 336 year: 2011 end-page: 341 ident: bib39 article-title: A prospective study of filaggrin null mutations in keratoconus patients with or without atopic disorders publication-title: Dermatology – volume: 47 start-page: 2820 year: 2006 end-page: 2822 ident: bib4 article-title: No VSX1 gene mutations associated with keratoconus publication-title: Invest Ophthalmol Vis Sci – volume: 63 start-page: 289 year: 2000 end-page: 293 ident: bib124 article-title: Isolation and characterization of a novel human paired- like homeodomain-containing transcription factor gene, VSX1, expressed in ocular tissues publication-title: Genomics – volume: 42 start-page: 297 year: 1998 end-page: 319 ident: bib114 article-title: Keratoconus publication-title: Surv Ophthalmol – volume: 117 start-page: 239 year: 2010 ident: bib147 article-title: Role of the hepatocyte growth factor gene in refractive error publication-title: Ophthalmology – volume: 11 start-page: 715 year: 2010 ident: bib58 article-title: miRNeye: a microRNA expression atlas of the mouse eye publication-title: BMC Genomics – volume: 14 start-page: 530 year: 2004 end-page: 536 ident: bib102 article-title: Regulation of retinal cone bipolar cell differentiation and photopic vision by the CVC homeobox gene Vsx1 publication-title: Curr Biol – volume: 33 start-page: 1371 year: 2007 end-page: 1375 ident: bib103 article-title: Corneal biomechanical properties in normal, post-laser in situ keratomileusis, and keratoconic eyes publication-title: J Cataract Refract Surg – volume: 113 start-page: 1633 year: 2006 end-page: 1638 ident: bib113 article-title: Extended long-term outcomes of penetrating keratoplasty for keratoconus publication-title: Ophthalmology – volume: 11 start-page: 1029 year: 2002 end-page: 1036 ident: bib49 article-title: : a gene for posterior polymorphous dystrophy and keratoconus publication-title: Hum Mol Genet – volume: 20 start-page: 375 year: 1976 end-page: 414 ident: bib112 article-title: Contributions of electron microscopy to the study of corneal pathology publication-title: Surv Ophthalmol – volume: 74 start-page: 473 year: 2002 end-page: 482 ident: bib129 article-title: Cellular incursion into Bowman's membrane in the peripheral cone of the keratoconic cornea publication-title: Exp Eye Res – volume: 17 start-page: 63 year: 1978 end-page: 65 ident: bib29 article-title: Collagen cross linking in keratoconus publication-title: Invest Ophthalmol Vis Sci – volume: 15 start-page: 1028 year: 2009 end-page: 1035 ident: bib152 article-title: Hepatocyte growth factor and myopia: genetic association analyses in a Caucasian population publication-title: Mol Vis – volume: 93 start-page: 191 year: 2009 end-page: 197 ident: bib106 article-title: Recurrent ectasia in corneal grafts and outcomes if repeat keratoplasty for keratoconus publication-title: Br J Ophthalmol – volume: 37 start-page: 14 year: 2009 end-page: 29 ident: bib19 article-title: An introduction to understanding elevation-based topography: how elevation data are displayed – a review publication-title: Clin Exp Ophthalmol – volume: 32 start-page: 129 year: 2009 end-page: 132 ident: bib125 article-title: Comparison of corneal biomechanics in pre and post refractive surgery and keratoconic eyes by the Ocular Response Analyzer publication-title: Cont Lens Anterior Eye – volume: 28 start-page: 189 year: 2014 end-page: 195 ident: bib36 article-title: The pathogenesis of keratoconus publication-title: Eye – volume: 111 start-page: 96 year: 1946 end-page: 101 ident: bib10 article-title: Keratocone classique et keratocone fruste, arguments unitaire publication-title: Ophthalmologica – volume: 362 start-page: 59 year: 1993 end-page: 62 ident: bib118 article-title: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis publication-title: Nature – volume: 29 start-page: 1180 year: 2010 end-page: 1185 ident: bib71 article-title: Unusual presentation of presumed posterior polymorphous dystrophy associated with iris heterochromia, band keratopathy, and keratoconus publication-title: Cornea – volume: 29 start-page: 172 year: 2010 end-page: 176 ident: bib133 article-title: Absence of pathogenic mutations in VSX1 and SOD1 genes in patients with keratoconus publication-title: Cornea – volume: 36 start-page: 522 year: 2011 end-page: 527 ident: bib89 article-title: Reduction in corneal volume with severity of keratoconus publication-title: Curr Eye Res – volume: 87 start-page: 905 year: 1980 end-page: 909 ident: bib109 article-title: Round and oval cones in keratoconus publication-title: Ophthalmology – volume: 156 start-page: 1102 year: 2013 end-page: 1111 ident: bib88 article-title: Expanding the cone location and magnitude index to include corneal thickness and posterior surface information for the detection of KCN publication-title: Am J Ophthalmol – volume: 46 start-page: 823 year: 2005 end-page: 832 ident: bib62 article-title: Increased levels of catalase and cathepsin V/L2 but decreased TIMP-1 in keratoconus corneas: Evidence that oxidative stress plays a role in this disorder publication-title: Invest Ophthalmol Vis Sci – volume: 19 start-page: 845 year: 2013 end-page: 851 ident: bib94 article-title: Interleukin 1 beta promoter polymorphism is associated with keratoconus in a Japanese population publication-title: Mol Vis – volume: 93 start-page: 820 year: 2009 end-page: 824 ident: bib76 article-title: Subclinical keratoconus and inflammatory molecules from tears publication-title: Br J Ophthalmol – volume: 32 start-page: 916 year: 2013 end-page: 921 ident: bib97 article-title: Correlation of anterior and posterior corneal shape in keratoconus publication-title: Cornea – volume: 67 start-page: 23 year: 1983 end-page: 28 ident: bib100 article-title: Recurrence if keratoconus in a donor cornea 22yrs after successful keratoplasty publication-title: Br J Ophthalmol – year: 2010 ident: bib12 article-title: Qualitative and quantitative analysis of aspheric symmetry and asymmetry on corneal surfaces publication-title: Poster presented at: the ASCRS Symposium and Congress – volume: 32 start-page: 696 year: 2013 end-page: 701 ident: bib79 article-title: An association between the publication-title: Cornea – volume: 26 start-page: 322 year: 2007 end-page: 324 ident: bib146 article-title: Recurrence of keratoconus in 2 corneal grafts after penetrating keratoplasty publication-title: Cornea – volume: 111 start-page: 828 year: 2004 end-page: 836 ident: bib95 article-title: VSX1 (RINX) mutation with craniofacial anomalies, empty sella, corneal endothelial changes, and abnormal retinal and auditory bipolar cells publication-title: Ophthalmology – volume: 48 start-page: 3026 year: 2007 end-page: 3031 ident: bib126 article-title: Assessment of the biomechanical properties of the cornea with the ocular response analyzer in normal and keratoconic eyes publication-title: Invest Ophthalmol Vis Sci – volume: 52 start-page: 8592 year: 2011 end-page: 8597 ident: bib13 article-title: Oxidative stress in keratoconus? publication-title: Invest Ophthalmol Vis Sci – volume: 1 start-page: 167 year: 2012 end-page: 172 ident: bib84 article-title: Correlation of topometric and topographic indices with visual acuity in patients with KCN publication-title: J Kerat Ect Cor Dis – volume: 17 start-page: 3128 year: 2011 end-page: 3136 ident: bib121 article-title: Mutation analysis of VSX1 and SOD1 in Iranian patients with keratoconus publication-title: Mol Vis – volume: 131 start-page: 653 year: 2001 end-page: 654 ident: bib69 article-title: Postkeratoplasty keratoconus in a non-keratoconic patient publication-title: Am J Ophthalmol – volume: 89 start-page: 628 year: 2011 end-page: 633 ident: bib55 article-title: Mutation altering the miR-184 seed region causes familial keratoconus with cataract publication-title: Am J Hum Genet – volume: 68 start-page: 434 year: 1974 end-page: 436 ident: bib56 article-title: Recurrence of keratoconus after keratoplasty publication-title: Z Artzl Fortbild (Jena) – volume: 26 start-page: 847 year: 2010 end-page: 849 ident: bib7 article-title: Imaging of the cornea: topography vs tomography publication-title: J Refract Surg – volume: 29 start-page: 53 year: 2008 end-page: 59 ident: bib41 article-title: The D144E substitution in the VSX1 gene: a non-pathogenic variant or a disease causing mutation? publication-title: Ophthalmic Genet – volume: 46 start-page: 1256 year: 2005 end-page: 1263 ident: bib14 article-title: Accumulation of mitochondrial DNA damage in keratoconus corneas publication-title: Invest Ophthalmol Vis Sci – volume: 17 start-page: 1145 year: 2006 end-page: 1149 ident: bib60 article-title: Comparative integromics on angiopoietin family members publication-title: Int J Mol Med – volume: 31 start-page: 156 issue: 1 year: 2005 ident: 10.1016/j.survophthal.2017.06.009_bib86 article-title: Determining in vivo biomechanical properties of the cornea with an ocular response analyzer publication-title: J Cataract Refract Surg doi: 10.1016/j.jcrs.2004.10.044 – volume: 3 start-page: 440 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib128 article-title: AAV serotype influences gene transfer in corneal stroma in vivo publication-title: Exp Eye Res doi: 10.1016/j.exer.2010.06.020 – start-page: 503 year: 2006 ident: 10.1016/j.survophthal.2017.06.009_bib52 – volume: 23 start-page: 594 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib20 article-title: Whole exome and whole genome sequencing publication-title: Curr Opin Pediatr doi: 10.1097/MOP.0b013e32834b20ec – volume: 113 start-page: 1633 issue: 9 year: 2006 ident: 10.1016/j.survophthal.2017.06.009_bib113 article-title: Extended long-term outcomes of penetrating keratoplasty for keratoconus publication-title: Ophthalmology doi: 10.1016/j.ophtha.2006.02.058 – volume: 18 start-page: 2598 year: 2012 ident: 10.1016/j.survophthal.2017.06.009_bib127 article-title: Attenuation of corneal myofibroblast development through nanoparticle-mediated soluble transforming growth factor-beta type II receptor (sTGFbetaRII) gene transfer publication-title: Mol Vis – volume: 46 start-page: 1256 year: 2005 ident: 10.1016/j.survophthal.2017.06.009_bib14 article-title: Accumulation of mitochondrial DNA damage in keratoconus corneas publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.04-1395 – volume: 29 start-page: 53 year: 2008 ident: 10.1016/j.survophthal.2017.06.009_bib41 article-title: The D144E substitution in the VSX1 gene: a non-pathogenic variant or a disease causing mutation? publication-title: Ophthalmic Genet doi: 10.1080/13816810802008242 – volume: 36 start-page: 522 issue: 6 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib89 article-title: Reduction in corneal volume with severity of keratoconus publication-title: Curr Eye Res doi: 10.3109/02713683.2011.553306 – volume: 29 start-page: 1180 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib71 article-title: Unusual presentation of presumed posterior polymorphous dystrophy associated with iris heterochromia, band keratopathy, and keratoconus publication-title: Cornea doi: 10.1097/ICO.0b013e3181d007e1 – volume: 175 start-page: 169 year: 2017 ident: 10.1016/j.survophthal.2017.06.009_bib45 article-title: Age-specific incidence and prevalence of keratoconus: a nationwide registration study publication-title: Am J Ophthalmol doi: 10.1016/j.ajo.2016.12.015 – volume: 17 start-page: 1145 year: 2006 ident: 10.1016/j.survophthal.2017.06.009_bib60 article-title: Comparative integromics on angiopoietin family members publication-title: Int J Mol Med – volume: 19 start-page: 845 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib94 article-title: Interleukin 1 beta promoter polymorphism is associated with keratoconus in a Japanese population publication-title: Mol Vis – ident: 10.1016/j.survophthal.2017.06.009_bib99 doi: 10.1167/iovs.02-0671 – volume: 1 start-page: 167 issue: 3 year: 2012 ident: 10.1016/j.survophthal.2017.06.009_bib84 article-title: Correlation of topometric and topographic indices with visual acuity in patients with KCN publication-title: J Kerat Ect Cor Dis – volume: 29 start-page: 274 issue: 4 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib130 article-title: Influence of the reference surface shape for discriminating between normal corneas, subclinical keratoconus and keratoconus publication-title: J Refract Surg doi: 10.3928/1081597X-20130318-07 – volume: 101 start-page: 1754 year: 2004 ident: 10.1016/j.survophthal.2017.06.009_bib31 article-title: Control of late off-center cone bipolar cell differentiation and visual signaling by the homeobox gene Vsx1 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0306520101 – volume: 20 start-page: 375 year: 1976 ident: 10.1016/j.survophthal.2017.06.009_bib112 article-title: Contributions of electron microscopy to the study of corneal pathology publication-title: Surv Ophthalmol doi: 10.1016/0039-6257(76)90066-7 – volume: 82 start-page: 1217 issue: 5 year: 2008 ident: 10.1016/j.survophthal.2017.06.009_bib3 article-title: Deleterious mutations in the Zinc-Finger 469 gene cause brittle cornea syndrome publication-title: Am J Hum Genet doi: 10.1016/j.ajhg.2008.04.001 – volume: 46 start-page: 39 year: 2005 ident: 10.1016/j.survophthal.2017.06.009_bib21 article-title: VSX1 mutational analysis in a series of Italian patients affected by keratoconus: detection of a novel mutation publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.04-0533 – volume: 112 start-page: 654 year: 2005 ident: 10.1016/j.survophthal.2017.06.009_bib74 article-title: Inflammatory molecules in the tears of patients with keratoconus publication-title: Ophthalmology doi: 10.1016/j.ophtha.2004.11.050 – volume: 51 start-page: 2403 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib123 article-title: Screening of forme fruste keratoconus with the ocular response analyzer publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.09-3689 – volume: 10 start-page: 451 year: 1996 ident: 10.1016/j.survophthal.2017.06.009_bib57 article-title: Topographic analysis in pellucid marginal degeneration and keratoglobus publication-title: Eye (Lond) doi: 10.1038/eye.1996.99 – volume: 54 start-page: 659 issue: 1 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib53 article-title: A new tonometer—the Corvis ST tonometer: clinical comparison with non-contact and Goldmann applanation tonometers publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.12-10984 – volume: 34 start-page: 160 issue: 3 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib148 article-title: Common single nucleotide polymorphisms and keratoconus in the Han Chinese population publication-title: Ophthalmic Genet doi: 10.3109/13816810.2012.743569 – volume: 11 start-page: 3 year: 2016 ident: 10.1016/j.survophthal.2017.06.009_bib40 article-title: Assessing progression of keratoconus: novel tomographic determinants publication-title: Eye Vis (Lond) – volume: 94 start-page: 1068 year: 1990 ident: 10.1016/j.survophthal.2017.06.009_bib136 article-title: Quantitative analysis of collagen fiberin keratoconus publication-title: Nihon Ganka Gakkai Zasshi – volume: 17 start-page: 737 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib149 article-title: Absence of Vsx1 expression in the normal and damaged mouse cornea publication-title: Mol Vis – volume: 114 start-page: 1020 issue: 5 year: 2007 ident: 10.1016/j.survophthal.2017.06.009_bib1 article-title: Vertical D: a novel topographic pattern in some keratoconus suspects publication-title: Ophthalmology doi: 10.1016/j.ophtha.2006.10.022 – volume: 31 start-page: 435 issue: 4 year: 1980 ident: 10.1016/j.survophthal.2017.06.009_bib11 article-title: Biomechanical properties of keratoconus and normal corneas publication-title: Exp Eye Res doi: 10.1016/S0014-4835(80)80027-3 – volume: 12 start-page: 745 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib15 article-title: sequencing as a tool for Mendelian disease gene discovery publication-title: Nat Rev Genet doi: 10.1038/nrg3031 – volume: 39 start-page: 1117 year: 1998 ident: 10.1016/j.survophthal.2017.06.009_bib153 article-title: Expression of degradative enzymes and protease inhibitors in corneas with keratoconus publication-title: Invest Ophthalmol Vis Sci – volume: 17 start-page: 63 year: 1978 ident: 10.1016/j.survophthal.2017.06.009_bib29 article-title: Collagen cross linking in keratoconus publication-title: Invest Ophthalmol Vis Sci – volume: 46 start-page: 823 year: 2005 ident: 10.1016/j.survophthal.2017.06.009_bib62 article-title: Increased levels of catalase and cathepsin V/L2 but decreased TIMP-1 in keratoconus corneas: Evidence that oxidative stress plays a role in this disorder publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.04-0549 – volume: 47 start-page: 3791 year: 2006 ident: 10.1016/j.survophthal.2017.06.009_bib80 article-title: Two-stage genome-wide linkage scan in keratoconus sib pair families publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.06-0214 – volume: 33 start-page: 1371 year: 2007 ident: 10.1016/j.survophthal.2017.06.009_bib103 article-title: Corneal biomechanical properties in normal, post-laser in situ keratomileusis, and keratoconic eyes publication-title: J Cataract Refract Surg doi: 10.1016/j.jcrs.2007.04.021 – volume: 26 start-page: 847 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib7 article-title: Imaging of the cornea: topography vs tomography publication-title: J Refract Surg doi: 10.3928/1081597X-20101006-01 – volume: 24 start-page: 1085 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib34 article-title: Mutational screening of VSX1 in keratoconus patients from the European population publication-title: Eye (Lond) doi: 10.1038/eye.2009.217 – volume: 1 start-page: 178 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib142 article-title: Corneal asphericity changes after implantation of intrastromal corneal ring segments in Keratoconus publication-title: J Emmetropia – volume: 47 start-page: 2820 year: 2006 ident: 10.1016/j.survophthal.2017.06.009_bib4 article-title: No VSX1 gene mutations associated with keratoconus publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.05-1530 – volume: 11 start-page: 1029 issue: 9 year: 2002 ident: 10.1016/j.survophthal.2017.06.009_bib49 article-title: VSX1: a gene for posterior polymorphous dystrophy and keratoconus publication-title: Hum Mol Genet doi: 10.1093/hmg/11.9.1029 – volume: 35 start-page: 2749 issue: 6 year: 1994 ident: 10.1016/j.survophthal.2017.06.009_bib87 article-title: Automated keratoconus screening with corneal topography analysis publication-title: Invest Ophthalmol Vis Sci – volume: 28 start-page: 189 year: 2014 ident: 10.1016/j.survophthal.2017.06.009_bib36 article-title: The pathogenesis of keratoconus publication-title: Eye doi: 10.1038/eye.2013.278 – volume: 29 start-page: 172 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib133 article-title: Absence of pathogenic mutations in VSX1 and SOD1 genes in patients with keratoconus publication-title: Cornea doi: 10.1097/ICO.0b013e3181aebf7a – volume: 37 start-page: 552 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib5 article-title: Keratoconus-integrated characterization considering anterior corneal aberrations, internal astigmatism, and corneal biomechanics publication-title: J Cataract Refract Surg doi: 10.1016/j.jcrs.2010.10.046 – volume: 28 start-page: 293 year: 1984 ident: 10.1016/j.survophthal.2017.06.009_bib67 article-title: Keratoconus and related non-inflammatory corneal thinning disorders publication-title: Surv Ophthalmol doi: 10.1016/0039-6257(84)90094-8 – volume: 68 start-page: 434 issue: 9 year: 1974 ident: 10.1016/j.survophthal.2017.06.009_bib56 article-title: Recurrence of keratoconus after keratoplasty publication-title: Z Artzl Fortbild (Jena) – volume: 2 start-page: 281 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib83 article-title: Quantitative trait loci associated with murine central corneal thickness publication-title: Physiol Genomics doi: 10.1152/physiolgenomics.00140.2009 – volume: 26 start-page: 139 year: 2003 ident: 10.1016/j.survophthal.2017.06.009_bib61 article-title: The cascade hypothesis of keratoconus publication-title: Cont Lens Anterior Eye doi: 10.1016/S1367-0484(03)00022-5 – volume: 4 start-page: 336 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib39 article-title: A prospective study of filaggrin null mutations in keratoconus patients with or without atopic disorders publication-title: Dermatology doi: 10.1159/000328408 – volume: 27 start-page: 758 year: 2008 ident: 10.1016/j.survophthal.2017.06.009_bib75 article-title: Inflammatory response to contact lenses in patients with keratoconus compared with myopic subjects publication-title: Cornea doi: 10.1097/ICO.0b013e31816a3591 – volume: 50 start-page: 1531 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib44 article-title: Localization of a gene for keratoconus to a 5.6-Mb interval on 13q32 publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.08-2173 – volume: 131 start-page: 653 issue: 5 year: 2001 ident: 10.1016/j.survophthal.2017.06.009_bib69 article-title: Postkeratoplasty keratoconus in a non-keratoconic patient publication-title: Am J Ophthalmol doi: 10.1016/S0002-9394(00)00885-0 – volume: 14 start-page: 625 issue: 4 year: 2000 ident: 10.1016/j.survophthal.2017.06.009_bib108 article-title: Does ethnic influence the incidence or severity of keratoconus publication-title: Eye doi: 10.1038/eye.2000.154 – volume: 25 start-page: 604 issue: 7 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib116 article-title: Corneal epithelial thickness profile in the diagnosis of keratoconus publication-title: J Refract Surg doi: 10.3928/1081597X-20090610-06 – volume: 10 start-page: 2 issue: 1 year: 1991 ident: 10.1016/j.survophthal.2017.06.009_bib151 article-title: Corneal topography of keratoconus publication-title: Cornea doi: 10.1097/00003226-199101000-00002 – volume: 84 start-page: 1125 year: 2007 ident: 10.1016/j.survophthal.2017.06.009_bib91 article-title: Changes in the balance of the tissue inhibitor of matrix metalloproteinases (TIMPs)-1 and -3 may promote keratocyte apoptosis in keratoconus publication-title: Exp Eye Res doi: 10.1016/j.exer.2007.02.013 – volume: 90 start-page: 672 year: 1980 ident: 10.1016/j.survophthal.2017.06.009_bib2 article-title: Recurrent keratoconus after keratoplasty publication-title: Am J Ophthalmol doi: 10.1016/S0002-9394(14)75135-9 – volume: 25 start-page: 1327 issue: 10 year: 1999 ident: 10.1016/j.survophthal.2017.06.009_bib115 article-title: KISA% index: a quantitive videokeratography algorithm embodying minimal topographic criteria for diagnosis keratoconus publication-title: J Cataract Refract Surg doi: 10.1016/S0886-3350(99)00195-9 – volume: 52 start-page: 8592 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib13 article-title: Oxidative stress in keratoconus? publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.11-7732 – volume: 5 start-page: 475 year: 1999 ident: 10.1016/j.survophthal.2017.06.009_bib65 article-title: Keratocyte apoptosis associated with keratoconus publication-title: Exp Eye Res doi: 10.1006/exer.1999.0719 – volume: 54 start-page: 2696 issue: 4 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib77 article-title: Genetic association of COL5A1 variants in keratoconus patients suggests a complex connection between corneal thinning and keratoconus publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.13-11601 – volume: 29 start-page: 469 year: 2015 ident: 10.1016/j.survophthal.2017.06.009_bib17 article-title: Acute corneal hydrops in keratoconus: a national prospective study of incidence and management publication-title: Eye doi: 10.1038/eye.2014.333 – volume: 15 start-page: 2480 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib73 article-title: Evaluation of differentially expressed genes identified in keratoconus publication-title: Mol Vis – volume: 156 start-page: 1102 issue: 6 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib88 article-title: Expanding the cone location and magnitude index to include corneal thickness and posterior surface information for the detection of KCN publication-title: Am J Ophthalmol doi: 10.1016/j.ajo.2013.07.018 – volume: 87 start-page: 122 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib30 article-title: The keratoconus corneal proteome: loss of epithelial integrity and stromal degeneration publication-title: J Proteomics doi: 10.1016/j.jprot.2013.05.023 – volume: 38 start-page: 43 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib134 article-title: Secreted frizzled-related protein 1 (SFRP1) is highly upregulated in keratoconus epithelium: A novel finding highlighting a new potential focus for keratoconus research and treatment publication-title: Clin Exp Ophthalmol doi: 10.1111/j.1442-9071.2009.02216.x – volume: 32 start-page: 696 issue: 5 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib79 article-title: An association between the calpastatin (CAST) gene and keratoconus publication-title: Cornea doi: 10.1097/ICO.0b013e3182821c1c – volume: 96 start-page: 1217 year: 1978 ident: 10.1016/j.survophthal.2017.06.009_bib66 article-title: Pellucid marginal corneal degeneration publication-title: Arch Ophthalmol doi: 10.1001/archopht.1978.03910060051009 – volume: 17 start-page: 3128 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib121 article-title: Mutation analysis of VSX1 and SOD1 in Iranian patients with keratoconus publication-title: Mol Vis – volume: 46 start-page: 1948 year: 2005 ident: 10.1016/j.survophthal.2017.06.009_bib93 article-title: Changes in collagen orientation and distribution in keratoconus corneas publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.04-1253 – volume: 51 start-page: 265 issue: 4 year: 2007 ident: 10.1016/j.survophthal.2017.06.009_bib135 article-title: Longitudinal changes in corneal irregular astigmatism and visual acuity in eyes with KCN publication-title: Jpn J Ophthalmol doi: 10.1007/s10384-007-0453-2 – volume: 93 start-page: 820 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib76 article-title: Subclinical keratoconus and inflammatory molecules from tears publication-title: Br J Ophthalmol doi: 10.1136/bjo.2008.144253 – volume: 32 start-page: 916 issue: 7 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib97 article-title: Correlation of anterior and posterior corneal shape in keratoconus publication-title: Cornea doi: 10.1097/ICO.0b013e3182904950 – volume: 116 issue: 4 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib64 article-title: Posterior elevation in keratoconus publication-title: Ophthalmology doi: 10.1016/j.ophtha.2009.01.009 – volume: 17 start-page: 481 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib105 article-title: Familial segregation of a VSX1 mutation adds a new dimension to its role in the causation of keratoconus publication-title: Mol Vis – volume: 36 start-page: 814 issue: 5 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib111 article-title: Corneal volume, pachymetry and correlation of anterior and posterior corneal shape in subclinical and different stages of clinical KCN publication-title: J Cataract Refract Surg doi: 10.1016/j.jcrs.2009.11.012 – volume: 156 start-page: 237 issue: 2 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib131 article-title: Detection of subclinical keratoconus using an automated decision tree classification publication-title: Am J Ophthalmol doi: 10.1016/j.ajo.2013.03.034 – volume: 19 start-page: R145 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib140 article-title: Exome sequencing: the sweet spot before whole genomes publication-title: Hum Mol Genet doi: 10.1093/hmg/ddq333 – volume: 45 start-page: 155 issue: 2 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib85 article-title: Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus publication-title: Nat Genet doi: 10.1038/ng.2506 – volume: 11 start-page: 715 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib58 article-title: miRNeye: a microRNA expression atlas of the mouse eye publication-title: BMC Genomics doi: 10.1186/1471-2164-11-715 – volume: 34 start-page: 359 year: 2015 ident: 10.1016/j.survophthal.2017.06.009_bib46 article-title: Global consensus on keratoconus and ectatic disease publication-title: Cornea doi: 10.1097/ICO.0000000000000408 – volume: 15 start-page: 2848 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib132 article-title: Polymorphisms in COL4A3 and COL4A4 genes associated with keratoconus publication-title: Mol Vis – volume: 33 start-page: 157 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib117 article-title: Keratoconus: a review publication-title: Cont Lens Anterior Eye doi: 10.1016/j.clae.2010.04.006 – volume: 286 start-page: 4951 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib119 article-title: Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp publication-title: J Biol Chem doi: 10.1074/jbc.M110.181099 – volume: 32 start-page: 1851 issue: 11 year: 2006 ident: 10.1016/j.survophthal.2017.06.009_bib6 article-title: Corneal-thickness spatial profile and corneal volume distribution: tomographic indices to detect keratoconus publication-title: J Cataract Refract Surg doi: 10.1016/j.jcrs.2006.06.025 – volume: 12 start-page: 1175 year: 2006 ident: 10.1016/j.survophthal.2017.06.009_bib120 article-title: MicroRNAs of the mammalian eye display distinct and overlapping tissue specificity publication-title: Mol Vis – volume: 53 start-page: 185 issue: 1 year: 2012 ident: 10.1016/j.survophthal.2017.06.009_bib122 article-title: Brillouin optical microscopy for corneal biomechanics publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.11-8281 – volume: 7 start-page: 163 issue: 3 year: 1988 ident: 10.1016/j.survophthal.2017.06.009_bib24 article-title: Keratoconus publication-title: Cornea doi: 10.1097/00003226-198803000-00001 – volume: 111 start-page: 96 year: 1946 ident: 10.1016/j.survophthal.2017.06.009_bib10 article-title: Keratocone classique et keratocone fruste, arguments unitaire publication-title: Ophthalmologica doi: 10.1159/000300309 – volume: 12 start-page: 499 year: 2006 ident: 10.1016/j.survophthal.2017.06.009_bib35 article-title: Fine mapping of the keratoconus with cataract locus on chromosome 15q and candidate gene analysis publication-title: Mol Vis – volume: 20 start-page: 389 year: 2012 ident: 10.1016/j.survophthal.2017.06.009_bib32 article-title: Novel mutation and three other sequence variants segregating with phenotype at keratoconus 13q32 susceptibility locus publication-title: Eur J Hum Genet doi: 10.1038/ejhg.2011.203 – volume: 38 start-page: 121 year: 1997 ident: 10.1016/j.survophthal.2017.06.009_bib37 article-title: Collagen fibril orientation in the human corneal stroma and its implication in keratoconus publication-title: Invest Ophthalmol Vis Sci – volume: 119 start-page: 511 issue: 4 year: 1995 ident: 10.1016/j.survophthal.2017.06.009_bib68 article-title: Histological evidence of recurrent keratoconus seven years after keratoplasty publication-title: Am J Ophthalmol doi: 10.1016/S0002-9394(14)71239-5 – volume: 7 start-page: 397 year: 2005 ident: 10.1016/j.survophthal.2017.06.009_bib138 article-title: Genomewide linkage scan in a multigeneration Caucasian pedigree identifies a novel locus for keratoconus on chromosome 5q14.3-q21.1 publication-title: Genet Med doi: 10.1097/01.GIM.0000170772.41860.54 – year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib12 article-title: Qualitative and quantitative analysis of aspheric symmetry and asymmetry on corneal surfaces – volume: 4 start-page: 85 issue: 3 year: 2015 ident: 10.1016/j.survophthal.2017.06.009_bib18 article-title: A new tomographic method of grading keratoconus: the ABCD Grading system publication-title: Int J Kerat Ect Cor Dis – volume: 50 start-page: 341 year: 2002 ident: 10.1016/j.survophthal.2017.06.009_bib25 article-title: Evidence of oxidative stress in human corneal diseases publication-title: J Histochem Cytochem doi: 10.1177/002215540205000306 – volume: 36 start-page: 3 year: 1959 ident: 10.1016/j.survophthal.2017.06.009_bib51 article-title: A keratoscopic survey of 13,395 eyes publication-title: Am J Optom Arch Am Acad Optom doi: 10.1097/00006324-195901000-00002 – volume: 47 start-page: 3345 year: 2006 ident: 10.1016/j.survophthal.2017.06.009_bib144 article-title: SOD1: a candidate gene for keratoconus publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.05-1500 – volume: 35 start-page: 1597 issue: 9 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib81 article-title: Keratoconus: Classification scheme based on videokeratography and clinical signs publication-title: J Cataract Refract Surg doi: 10.1016/j.jcrs.2009.03.050 – volume: 63 start-page: 289 year: 2000 ident: 10.1016/j.survophthal.2017.06.009_bib124 article-title: Isolation and characterization of a novel human paired- like homeodomain-containing transcription factor gene, VSX1, expressed in ocular tissues publication-title: Genomics doi: 10.1006/geno.1999.6093 – volume: 74 start-page: 473 issue: 4 year: 2002 ident: 10.1016/j.survophthal.2017.06.009_bib129 article-title: Cellular incursion into Bowman's membrane in the peripheral cone of the keratoconic cornea publication-title: Exp Eye Res doi: 10.1006/exer.2001.1157 – volume: 40 start-page: 870 year: 2014 ident: 10.1016/j.survophthal.2017.06.009_bib110 article-title: In vivo characterization of corneal biomechanics publication-title: J Cataract Refract Surg doi: 10.1016/j.jcrs.2014.03.021 – year: 2012 ident: 10.1016/j.survophthal.2017.06.009_bib150 article-title: The genetics of keratoconus: A review publication-title: Reprod Syst Sex Disord – volume: 37 start-page: 160 issue: 2 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib92 article-title: 150 years of practical observations in the conical cornea – what have we learned? publication-title: Clin Exp Ophthalmol doi: 10.1111/j.1442-9071.2009.02009.x – volume: 52 start-page: 8514 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib26 article-title: Association of polymorphisms in the hepatocyte growth factor gene promoter with keratoconus publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.11-8261 – volume: 43 start-page: 3160 year: 2002 ident: 10.1016/j.survophthal.2017.06.009_bib143 article-title: A locus for autosomal dominant keratoconus: linkage to 16q22.3-q23.1 in Finnish families publication-title: Invest Ophthalmol Vis Sci – volume: 54 start-page: 3215 issue: 5 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib72 article-title: Mutational spectrum of the ZEB1 gene in corneal dystrophies supports a genotype-phenotype correlation publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.13-11781 – volume: 21 start-page: 421 year: 2012 ident: 10.1016/j.survophthal.2017.06.009_bib78 article-title: A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries publication-title: Hum Mol Genet doi: 10.1093/hmg/ddr460 – volume: 178 start-page: 289 issue: 5 year: 1979 ident: 10.1016/j.survophthal.2017.06.009_bib33 article-title: Value of therapeutic soft contact lenses in the treatment of recurrent corneal erosions publication-title: Ophthalmologica doi: 10.1159/000308839 – volume: 25 start-page: 357 issue: 4 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib70 article-title: Circular keratotomy to reduce astigmatism and improve vision in stage I and II keratoconus publication-title: J Refract Surg doi: 10.3928/1081597X-20090401-07 – volume: 111 start-page: 828 year: 2004 ident: 10.1016/j.survophthal.2017.06.009_bib95 article-title: VSX1 (RINX) mutation with craniofacial anomalies, empty sella, corneal endothelial changes, and abnormal retinal and auditory bipolar cells publication-title: Ophthalmology doi: 10.1016/j.ophtha.2003.07.006 – volume: 48 start-page: 1087 issue: 3 year: 2007 ident: 10.1016/j.survophthal.2017.06.009_bib98 article-title: Second harmonic imaging microscopy of normal and keratoconus cornea publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.06-1177 – volume: 190 start-page: 293 year: 1974 ident: 10.1016/j.survophthal.2017.06.009_bib47 article-title: Zur genetic des keratoconus publication-title: Albrecht Von Graefes Arch Klin Exp Ophthalmol doi: 10.1007/BF00407890 – volume: 17 start-page: 2482 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib38 article-title: Mutational screening of VSX1, SPARC, SOD1, LOX, and TIMP3 in keratoconus publication-title: Mol Vis – volume: 362 start-page: 59 year: 1993 ident: 10.1016/j.survophthal.2017.06.009_bib118 article-title: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis publication-title: Nature doi: 10.1038/362059a0 – volume: 11 start-page: 1016 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib16 article-title: E2-2 protein and Fuchs's corneal dystrophy publication-title: N Engl J Med doi: 10.1056/NEJMoa1007064 – volume: 13 start-page: 1887 year: 2007 ident: 10.1016/j.survophthal.2017.06.009_bib82 article-title: Molecular analysis of the VSX1 gene in familial keratoconus publication-title: Mol Vis – volume: 28 start-page: 902 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib145 article-title: SOD1 haplotypes in familial keratoconus publication-title: Cornea doi: 10.1097/ICO.0b013e3181983a0c – volume: 15 start-page: 1028 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib152 article-title: Hepatocyte growth factor and myopia: genetic association analyses in a Caucasian population publication-title: Mol Vis – volume: 17 start-page: 1514 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib107 article-title: Mitochondrial complex 1 gene analysis in keratoconus publication-title: Mol Vis – volume: 67 start-page: 23 issue: 1 year: 1983 ident: 10.1016/j.survophthal.2017.06.009_bib100 article-title: Recurrence if keratoconus in a donor cornea 22yrs after successful keratoplasty publication-title: Br J Ophthalmol doi: 10.1136/bjo.67.1.23 – volume: 89 start-page: 628 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib55 article-title: Mutation altering the miR-184 seed region causes familial keratoconus with cataract publication-title: Am J Hum Genet doi: 10.1016/j.ajhg.2011.09.014 – volume: 8 start-page: 210 year: 2002 ident: 10.1016/j.survophthal.2017.06.009_bib101 article-title: Superoxide dismutase–applications and relevance to human diseases publication-title: Med Sci Monit – volume: 32 start-page: 129 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib125 article-title: Comparison of corneal biomechanics in pre and post refractive surgery and keratoconic eyes by the Ocular Response Analyzer publication-title: Cont Lens Anterior Eye doi: 10.1016/j.clae.2008.12.009 – volume: 53 start-page: 842 year: 2008 ident: 10.1016/j.survophthal.2017.06.009_bib96 article-title: VSX1 gene variants are associated with keratoconus in unrelated Korean patients publication-title: J Hum Genet doi: 10.1007/s10038-008-0319-6 – volume: 15 start-page: 2475 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib104 article-title: A novel VSX1 mutation identified in an individual with keratoconus in India publication-title: Mol Vis – volume: 87 start-page: 905 year: 1980 ident: 10.1016/j.survophthal.2017.06.009_bib109 article-title: Round and oval cones in keratoconus publication-title: Ophthalmology doi: 10.1016/S0161-6420(80)35145-2 – volume: 22 start-page: 330 issue: 4 year: 2002 ident: 10.1016/j.survophthal.2017.06.009_bib141 article-title: Recurrent keratoconus 40 years after keratoplasty publication-title: Ophthalmic Physiol Opt doi: 10.1046/j.1475-1313.2002.00046.x – volume: 42 start-page: 297 year: 1998 ident: 10.1016/j.survophthal.2017.06.009_bib114 article-title: Keratoconus publication-title: Surv Ophthalmol doi: 10.1016/S0039-6257(97)00119-7 – volume: 110 start-page: 1920 year: 2003 ident: 10.1016/j.survophthal.2017.06.009_bib23 article-title: Recurrence of keratoconus characteristics: a clinical and histological follow-up analysis of donor grafts publication-title: Ophthalmology doi: 10.1016/S0161-6420(03)00617-1 – volume: 117 start-page: 239 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib147 article-title: Role of the hepatocyte growth factor gene in refractive error publication-title: Ophthalmology doi: 10.1016/j.ophtha.2009.07.002 – volume: 117 start-page: 673 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib43 article-title: Corneal biomechanical metrics and anterior segment parameters in mild keratoconus publication-title: Ophthalmology doi: 10.1016/j.ophtha.2009.09.023 – volume: 67 start-page: 128 year: 2000 ident: 10.1016/j.survophthal.2017.06.009_bib48 article-title: RINX(VSX1), a novel homeobox gene expressed in the inner nuclear layer of the adult retina publication-title: Genomics doi: 10.1006/geno.2000.6248 – volume: 50 start-page: 1081 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib22 article-title: Linkage analysis in keratoconus: replication of locus 5q21.2 and identification of other suggestive Loci publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.08-2382 – volume: 16 start-page: 2395 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib139 article-title: VSX1 gene analysis in keratoconus publication-title: Mol Vis – volume: 26 start-page: 322 issue: 3 year: 2007 ident: 10.1016/j.survophthal.2017.06.009_bib146 article-title: Recurrence of keratoconus in 2 corneal grafts after penetrating keratoplasty publication-title: Cornea doi: 10.1097/ICO.0b013e31802c9e2e – volume: 17 start-page: 827 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib59 article-title: Sequence variants in COL4A1 and COL4A2 genes in Ecuadorian families with keratoconus publication-title: Mol Vis – volume: 48 start-page: 3026 year: 2007 ident: 10.1016/j.survophthal.2017.06.009_bib126 article-title: Assessment of the biomechanical properties of the cornea with the ocular response analyzer in normal and keratoconic eyes publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.04-0694 – volume: 93 start-page: 191 issue: 2 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib106 article-title: Recurrent ectasia in corneal grafts and outcomes if repeat keratoplasty for keratoconus publication-title: Br J Ophthalmol doi: 10.1136/bjo.2008.142117 – volume: 2 start-page: 146 year: 2013 ident: 10.1016/j.survophthal.2017.06.009_bib27 article-title: Insights into keratoconus from a genetic perspective publication-title: Clin Exp Optom doi: 10.1111/cxo.12024 – volume: 14 start-page: 530 year: 2004 ident: 10.1016/j.survophthal.2017.06.009_bib102 article-title: Regulation of retinal cone bipolar cell differentiation and photopic vision by the CVC homeobox gene Vsx1 publication-title: Curr Biol doi: 10.1016/j.cub.2004.02.027 – volume: 51 start-page: 11 issue: 2 year: 2011 ident: 10.1016/j.survophthal.2017.06.009_bib8 article-title: Evaluation of corneal shape and biomechanics before LASIK publication-title: Int Ophthalmol Clin doi: 10.1097/IIO.0b013e31820f1d2d – volume: 2 start-page: 166 year: 2010 ident: 10.1016/j.survophthal.2017.06.009_bib90 article-title: Genome-wide association studies and assessment of the risk of disease publication-title: N Engl J Med doi: 10.1056/NEJMra0905980 – volume: 27 start-page: 189 year: 2008 ident: 10.1016/j.survophthal.2017.06.009_bib137 article-title: Three VSX1 gene mutations, L159M, R166W, and H244R, are not associated with keratoconus publication-title: Cornea doi: 10.1097/ICO.0b013e31815a50e7 – volume: 96 start-page: 77 year: 1938 ident: 10.1016/j.survophthal.2017.06.009_bib9 article-title: Le keratocone fruste au javal publication-title: Ophthalmologica doi: 10.1159/000299577 – volume: 7 start-page: 4152 year: 2012 ident: 10.1016/j.survophthal.2017.06.009_bib28 article-title: Variation in the lysyl oxidase (LOX) gene is associated with keratoconus in family-based and case-control studies publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.11-9268 – volume: 13 start-page: 114 issue: 2 year: 1994 ident: 10.1016/j.survophthal.2017.06.009_bib63 article-title: Increased gelatinolytic activity in keratoconus cultures. A correlation to an altered matrix metalloproteinase-2/tissue inhibitor of metalloproteinase ratio publication-title: Cornea doi: 10.1097/00003226-199403000-00003 – volume: 14 start-page: 71 year: 2008 ident: 10.1016/j.survophthal.2017.06.009_bib54 article-title: Genetic analysis of chromosome 20-related posterior polymorphous corneal dystrophy: genetic heterogeneity and exclusion of three candidate genes publication-title: Mol Vis – volume: 37 start-page: 14 year: 2009 ident: 10.1016/j.survophthal.2017.06.009_bib19 article-title: An introduction to understanding elevation-based topography: how elevation data are displayed – a review publication-title: Clin Exp Ophthalmol doi: 10.1111/j.1442-9071.2008.01821.x – volume: 7 start-page: 328 issue: 4 year: 2012 ident: 10.1016/j.survophthal.2017.06.009_bib42 article-title: Recurrent keratoconus in corneal graft after DALK procedure publication-title: J Ophthalmic Vis Res – volume: 4 start-page: 485 year: 1995 ident: 10.1016/j.survophthal.2017.06.009_bib50 article-title: Linkage of posterior polymorphous corneal dystrophy to 20q11 publication-title: Hum Mol Genet doi: 10.1093/hmg/4.3.485 |
| SSID | ssj0004397 |
| Score | 2.6481984 |
| SecondaryResourceType | review_article |
| Snippet | We discuss new approaches to the early detection of keratoconus and recent investigations regarding the nature of its pathophysiology. We review the current... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 770 |
| SubjectTerms | Biomechanical Phenomena Corneal Topography - methods Diagnostic Techniques, Ophthalmological Eye Proteins - genetics Genetic Loci Genetic Predisposition to Disease genetics Humans Intercellular Signaling Peptides and Proteins - genetics keratoconus Keratoconus - diagnosis Keratoconus - genetics Keratoconus - physiopathology Mass Screening - methods MicroRNAs - genetics Mutation review article Risk Factors |
| Title | A review of keratoconus: Diagnosis, pathophysiology, and genetics |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S0039625717300462 https://dx.doi.org/10.1016/j.survophthal.2017.06.009 https://www.ncbi.nlm.nih.gov/pubmed/28688894 https://www.proquest.com/docview/1917665610 |
| Volume | 62 |
| WOSCitedRecordID | wos000413887500002&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVESC databaseName: Elsevier SD Freedom Collection Journals 2021 customDbUrl: eissn: 1879-3304 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0004397 issn: 0039-6257 databaseCode: AIEXJ dateStart: 19950101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Jb9QwFLamLaq4VKxlWKpU4tZGym674jJAEVS0QjBUc4scxxa0Q1Jlmbb_gx_Mc-wsLRoxIHGJokTPGud98za_BaGXoHKExzC2E8xDO5BpYBOSSlv4GAxoikXYzAY8_YhPTshsRj-NRj_bWpjFHGcZubqiF_-V1fAMmK1KZ_-C3d2i8ADugelwBbbDdSXGTwblKOeqZXIOLm_dZL691Xl1uq2AmkWcN4GNrmBFBdFhXVXXWA6t1i91sRDNUTwQVN_Y_MeNYPwxK_emdcP6U9H02mX9K66rYPTRviiuu4yOI3bNystm3sDeZ3Yuyi4wrRJwXoMTX91MujexCdB3bhebMPLWpzZ4WHgobyNvgKuh8MR6hIjRw1gPuPlNxOtowxnolmJhNq0y9HDThtWhvV5rz_JvqbsuCbHNbzuLB0vFaqm4yfWja2jDwyEFWbkx-XA4O-rrbX2qe7Ga3W2i3T5vcMnvWmb3LPNrGvtmeg9tGcfEmmhA3UcjkT1Am8cm9eIhmkwsjSsrl9YAVwdWh6p96xam9i1AlNUi6hH6-u5w-ua9beZv2Dx03MpOo5BHDk-DSFAiIuY5aSoJ3EnqYErcEHydCOz5FJzOgEfYh4skFCciYTLl0n-M1rM8E0-QRalwEuH7nlQ99UKeEFe6MnGTlIDDz9kYkfbrxNw0p1czUubxH7k0Rl5HeqE7tKxCdNCyIG5LkEFpxgCyVYhfdcTGTtX256rkuy3PY5Dl6oCOZSKvy1jFTqJIeTRjtK3B0G3JIxGBbxU8_ZftPkN3-7_nc7ReFbV4ge7wRfW9LHbQGp6RHQPyXyC20tQ |
| linkProvider | Elsevier |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+review+of+keratoconus%3A+Diagnosis%2C+pathophysiology%2C+and+genetics&rft.jtitle=Survey+of+ophthalmology&rft.au=Mas+Tur%2C+Veronica&rft.au=MacGregor%2C+Cheryl&rft.au=Jayaswal%2C+Rakesh&rft.au=O%27Brart%2C+David&rft.date=2017-11-01&rft.issn=0039-6257&rft.volume=62&rft.issue=6&rft.spage=770&rft.epage=783&rft_id=info:doi/10.1016%2Fj.survophthal.2017.06.009&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_survophthal_2017_06_009 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0039-6257&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0039-6257&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0039-6257&client=summon |