Data-driven Modeling of Hemodynamics and its Role on Thrombus Size and Shape in Aortic Dissections

Aortic dissection is a pathology that manifests due to microstructural defects in the aortic wall. Blood enters the damaged wall through an intimal tear, thereby creating a so-called false lumen and exposing the blood to thrombogenic intramural constituents such as collagen. The natural history of t...

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Bibliographic Details
Published in:	Scientific reports Vol. 8; no. 1; pp. 2515 - 18
Main Authors:	Yazdani, Alireza, Li, He, Bersi, Matthew R., Di Achille, Paolo, Insley, Joseph, Humphrey, Jay D., Karniadakis, George Em
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 06.02.2018 Nature Publishing Group
Subjects:	60 APPLIED LIFE SCIENCES 631/1647/245/2226 639/166/985 Aneurysm, Dissecting - pathology Animal models Animals Aorta Aortic dissection Blood Blood clots Blood levels Catheters Circulatory system Collagen Decision making Disease Models, Animal Hemodynamics Hemodynamics - physiology Humanities and Social Sciences Male Mice Mice, Knockout, ApoE Models, Cardiovascular multidisciplinary Science Science (multidisciplinary) Thrombosis Thrombosis - pathology
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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