Optogenetic induction of cortical spreading depression in anesthetized and freely behaving mice

Cortical spreading depression, which plays an important role in multiple neurological disorders, has been studied primarily with experimental models that use highly invasive methods. We developed a relatively non-invasive optogenetic model to induce cortical spreading depression by transcranial stim...

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Vydáno v:	Journal of cerebral blood flow and metabolism Ročník 37; číslo 5; s. 1641 - 1655
Hlavní autoři:	Houben, Thijs, Loonen, Inge Cm, Baca, Serapio M, Schenke, Maarten, Meijer, Johanna H, Ferrari, Michel D, Terwindt, Gisela M, Voskuyl, Rob A, Charles, Andrew, van den Maagdenberg, Arn Mjm, Tolner, Else A
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.05.2017
Témata:	Action Potentials - physiology Anesthesia Animals Bacterial Proteins - genetics Behavior, Animal - physiology Cerebrovascular Circulation - physiology Channelrhodopsins Cortical Spreading Depression - physiology Female Laser-Doppler Flowmetry Luminescent Proteins - genetics Male Mice, Transgenic Optogenetics Photic Stimulation Recombinant Fusion Proteins - genetics vascular dynamics non-invasive Behavior electrophysiology optogenetics
ISSN:	1559-7016
On-line přístup:	Zjistit podrobnosti o přístupu
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