Integrating noninvasive molecular imaging into molecular medicine: an evolving paradigm

Molecular imaging is a rapidly emerging field, providing noninvasive visual quantitative representations of fundamental biological processes in intact living subjects. Fundamental biomedical research stands to benefit considerably from advances in molecular imaging, with improved molecular target se...

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Bibliographic Details
Published in:Trends in molecular medicine Vol. 13; no. 5; pp. 183 - 191
Main Authors: Massoud, Tarik F., Gambhir, Sanjiv S.
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01.05.2007
Subjects:
Animals
Biomedical Research - methods
Diagnostic Imaging - methods
Diagnostic Imaging - trends
Drug Design
Humans
Mice
Models, Animal
Models, Biological
Molecular Diagnostic Techniques
Nuclear Medicine - trends
Pathology
Systems Biology - methods
Systems Biology - trends
ISSN:1471-4914, 1471-499X
Online Access:Get full text
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Summary:Molecular imaging is a rapidly emerging field, providing noninvasive visual quantitative representations of fundamental biological processes in intact living subjects. Fundamental biomedical research stands to benefit considerably from advances in molecular imaging, with improved molecular target selection, probe development and imaging instrumentation. The noninvasiveness of molecular imaging technologies will also provide benefit through improved patient care. Molecular imaging endpoints can be quantified, and therefore are particularly useful for translational research. Integration of the two disciplines of molecular imaging and molecular medicine, combined with systems-biology approaches to understanding disease complexity, promises to provide predictive, preventative and personalized medicine that will transform healthcare.
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ISSN:1471-4914
1471-499X
DOI:10.1016/j.molmed.2007.03.003