Interplay between alpha/beta and gamma interferons with B, T, and natural killer cells in the defense against herpes simplex virus type 1

The essential components of the immune system that control primary and chronic infection with herpes simplex virus type 1 (HSV-1) in mice were investigated. Infection within the first few days can be controlled by alpha/beta interferon (IFN-alpha/beta) alone without significant contribution of B, T,...

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Bibliographic Details
Published in:	Journal of virology Vol. 78; no. 8; p. 3846
Main Authors:	Vollstedt, Sabine, Arnold, Susi, Schwerdel, Cornelia, Franchini, Marco, Alber, Gottfried, Di Santo, James P, Ackermann, Mathias, Suter, Mark
Format:	Journal Article
Language:	English
Published:	United States 01.04.2004
Subjects:	Animals B-Lymphocytes - immunology Central Nervous System Infections - immunology Central Nervous System Infections - virology DNA, Viral - isolation & purification Herpes Simplex - immunology Herpes Simplex - virology Herpesvirus 1, Human - immunology Herpesvirus 1, Human - isolation & purification Herpesvirus 1, Human - pathogenicity Interferon gamma Receptor Interferons - physiology Killer Cells, Natural - immunology Lymphocyte Subsets - immunology Membrane Proteins Mice Mice, Congenic Mice, Inbred C57BL Mice, Knockout Receptor, Interferon alpha-beta Receptors, Interferon - deficiency Receptors, Interferon - genetics Receptors, Interferon - physiology T-Lymphocytes - immunology
ISSN:	0022-538X
Online Access:	Get more information
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