Once Overlooked, Now Made Visible: ATL Proteins and DNA Repair

Damage report: Alkyltransferase‐like proteins (ATLs) flip DNA lesions out of the DNA duplex but have no catalytic function. They act as recognition proteins that mark DNA lesions and allow repair (see picture; NER=nucleotide excision repair).

Bibliographic Details

Published in:	Angewandte Chemie (International ed.) Vol. 48; no. 40; pp. 7293 - 7295
Main Authors:	Reißner, Thomas, Schorr, Stephanie, Carell, Thomas
Format:	Journal Article
Language:	English
Published:	Weinheim Wiley-VCH Verlag 21.09.2009 WILEY-VCH Verlag WILEY‐VCH Verlag
Subjects:	Alkyl and Aryl Transferases - chemistry Alkyl and Aryl Transferases - metabolism Alkylating Agents - chemistry Alkylation DNA lesions DNA Repair Escherichia coli Proteins - chemistry Escherichia coli Proteins - metabolism molecular recognition nucleotides O-Methylguanine-DNA Methyltransferase - chemistry O-Methylguanine-DNA Methyltransferase - metabolism
ISSN:	1433-7851, 1521-3773, 1521-3773
Online Access:	Get full text
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