Functional disintegration in paranoid schizophrenia using resting-state fMRI

Functional disintegration has been observed in schizophrenia during task performance. We sought to investigate functional disintegration during rest because an intrinsic functional brain organization, including both “task-negative” (i.e., “default mode”) and “task-positive” networks, has been sugges...

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Bibliographic Details
Published in:	Schizophrenia research Vol. 97; no. 1; pp. 194 - 205
Main Authors:	Zhou, Yuan, Liang, Meng, Tian, Lixia, Wang, Kun, Hao, Yihui, Liu, Haihong, Liu, Zhening, Jiang, Tianzi
Format:	Journal Article
Language:	English
Published:	Amsterdam Elsevier B.V 01.12.2007 Elsevier Science
Subjects:	Adolescent Adult Adult and adolescent clinical studies Biological and medical sciences Cerebral Cortex - physiopathology Dominance, Cerebral - physiology Female fMRI Functional connectivity Gyrus Cinguli - physiopathology Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Medical sciences Motor Cortex - physiopathology Nerve Net - physiopathology Parietal Lobe - physiopathology Prefrontal Cortex - physiopathology Psychiatric/Mental Health Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Reference Values Rest - physiology Resting-state Schizophrenia Schizophrenia, Paranoid - diagnosis Schizophrenia, Paranoid - physiopathology Schizophrenia, Paranoid - psychology Temporal Lobe - physiopathology Functional connectivity IPL LP Schizophrenia MNI IFG L PHG SMA/pre-SMA Ins MFG OFG R BOLD dPM dMPFC PCu DLPFC MT Resting-state PCC PostCG fMRI ITG CPL cerebellar posterior lobe supplementary motor area/pre-supplementary motor area postcentral gyrus insula dorsolateral prefrontal cortex orbital frontal gyrus blood oxygen level-dependent lateral parietal region inferior frontal gyrus right middle temporal region Montreal Neurological Institute dorsal medial prefrontal cortex left middle frontal gyrus precuneus inferior parietal lobule inferior temporal gyrus parahippocampus gyrus posterior cingulated cortex dorsal premotor cortex Psychosis Human Rest Paranoid schizophrenia Medical imagery Nuclear magnetic resonance imaging Functional imaging
ISSN:	0920-9964, 1573-2509
Online Access:	Get full text
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