Role of RNA modifications in cancer

Specific chemical modifications of biological molecules are an efficient way of regulating molecular function, and a plethora of downstream signalling pathways are influenced by the modification of DNA and proteins. Many of the enzymes responsible for regulating protein and DNA modifications are tar...

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Bibliographic Details
Published in:	Nature reviews. Cancer Vol. 20; no. 6; pp. 303 - 322
Main Authors:	Barbieri, Isaia, Kouzarides, Tony
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.06.2020 Nature Publishing Group
Subjects:	631/337/1645/2570 631/67/1059 631/67/68/2486 Biomedical and Life Sciences Biomedicine Cancer Cancer Research Cancer therapies Care and treatment Deoxyribonucleic acid DNA Enzymes Epigenesis, Genetic - genetics Epigenesis, Genetic - physiology Health aspects Humans Molecular Targeted Therapy mRNA Neoplasms - drug therapy Neoplasms - genetics Neoplasms - metabolism Non-coding RNA Review Article RNA RNA - genetics RNA - metabolism RNA modification RNA Processing, Post-Transcriptional - genetics RNA Processing, Post-Transcriptional - physiology RNA, Messenger - genetics RNA, Messenger - metabolism rRNA Signal transduction Transcription Transfer RNA United Kingdom
ISSN:	1474-175X, 1474-1768, 1474-1768
Online Access:	Get full text
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