Role of RNA modifications in cancer

Specific chemical modifications of biological molecules are an efficient way of regulating molecular function, and a plethora of downstream signalling pathways are influenced by the modification of DNA and proteins. Many of the enzymes responsible for regulating protein and DNA modifications are tar...

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Veröffentlicht in:	Nature reviews. Cancer Jg. 20; H. 6; S. 303 - 322
Hauptverfasser:	Barbieri, Isaia, Kouzarides, Tony
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Nature Publishing Group 01.06.2020
Schlagworte:	Cancer Cancer therapies Deoxyribonucleic acid DNA Epigenesis, Genetic - genetics Epigenesis, Genetic - physiology Humans Molecular Targeted Therapy mRNA Neoplasms - drug therapy Neoplasms - genetics Neoplasms - metabolism Non-coding RNA RNA - genetics RNA - metabolism RNA modification RNA Processing, Post-Transcriptional - genetics RNA Processing, Post-Transcriptional - physiology RNA, Messenger - genetics RNA, Messenger - metabolism rRNA Signal transduction Transcription Transfer RNA
ISSN:	1474-175X, 1474-1768, 1474-1768
Online-Zugang:	Volltext
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