Enhanced activity of macrophage M1/M2 phenotypes in periodontitis

•In this study, we are the first one to find that the ratio of M1/M2 was significant higher in periodontitis group compared with that in gingivitis one.•In addition, the relative expressions of IL-1β and MMP-9 also increased in periodontitis group and was correlated with the ratios of M1/M2.•PD was...

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Bibliographic Details
Published in:	Archives of oral biology Vol. 96; pp. 234 - 242
Main Authors:	Yang, Jingmei, Zhu, Yan, Duan, Dingyu, Wang, Panpan, Xin, Yuejiao, Bai, Lin, Liu, Yiying, Xu, Yi
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.12.2018
Subjects:	Adult Advanced Basic Science Cytokine Dentistry Female Gingivitis - metabolism Humans Immunohistochemistry Interleukin-1beta - metabolism Macrophage Macrophages - metabolism Male Matrix Metalloproteinase 9 - metabolism Periodontal disease Periodontal Index Periodontitis - metabolism Phenotype Real-Time Polymerase Chain Reaction Periodontal disease Cytokine Macrophage
ISSN:	0003-9969, 1879-1506, 1879-1506
Online Access:	Get full text
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