The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man

The androgen receptor (AR) regulates prostate cell growth in man, and prostate cancer is the commonest cancer in men in the UK. We present a comprehensive analysis of AR binding sites in human prostate cancer tissues, including castrate-resistant prostate cancer (CRPC). We identified thousands of AR...

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Veröffentlicht in:	Cancer cell Jg. 23; H. 1; S. 35
Hauptverfasser:	Sharma, Naomi L, Massie, Charlie E, Ramos-Montoya, Antonio, Zecchini, Vincent, Scott, Helen E, Lamb, Alastair D, MacArthur, Stewart, Stark, Rory, Warren, Anne Y, Mills, Ian G, Neal, David E
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 14.01.2013
Schlagworte:	Animals Binding Sites Cell Line, Tumor Gene Expression Regulation, Neoplastic Histones - metabolism Humans Male Mice Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Receptors, Androgen - metabolism Receptors, Androgen - physiology
ISSN:	1878-3686, 1878-3686
Online-Zugang:	Weitere Angaben
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