Global left atrial failure in heart failure
The left atrium plays an important role in the maintenance of cardiovascular and neurohumoral homeostasis in heart failure. However, with progressive left ventricular dysfunction, left atrial (LA) dilation and mechanical failure develop, which frequently culminate in atrial fibrillation. Moreover, L...
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| Vydané v: | European journal of heart failure Ročník 18; číslo 11; s. 1307 - 1320 |
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| Hlavní autori: | , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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Oxford, UK
John Wiley & Sons, Ltd
01.11.2016
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| ISSN: | 1388-9842, 1879-0844 |
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| Abstract | The left atrium plays an important role in the maintenance of cardiovascular and neurohumoral homeostasis in heart failure. However, with progressive left ventricular dysfunction, left atrial (LA) dilation and mechanical failure develop, which frequently culminate in atrial fibrillation. Moreover, LA mechanical failure is accompanied by LA endocrine failure [deficient atrial natriuretic peptide (ANP) processing‐synthesis/development of ANP resistance) and LA regulatory failure (dominance of sympathetic nervous system excitatory mechanisms, excessive vasopressin release) contributing to neurohumoral overactivity, vasoconstriction, and volume overload (global LA failure). The purpose of the present review is to describe the characteristics and emphasize the clinical significance of global LA failure in patients with heart failure. |
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| AbstractList | The left atrium plays an important role in the maintenance of cardiovascular and neurohumoral homeostasis in heart failure. However, with progressive left ventricular dysfunction, left atrial (LA) dilation and mechanical failure develop, which frequently culminate in atrial fibrillation. Moreover, LA mechanical failure is accompanied by LA endocrine failure [deficient atrial natriuretic peptide (ANP) processing-synthesis/development of ANP resistance) and LA regulatory failure (dominance of sympathetic nervous system excitatory mechanisms, excessive vasopressin release) contributing to neurohumoral overactivity, vasoconstriction, and volume overload (global LA failure). The purpose of the present review is to describe the characteristics and emphasize the clinical significance of global LA failure in patients with heart failure. The left atrium plays an important role in the maintenance of cardiovascular and neurohumoral homeostasis in heart failure. However, with progressive left ventricular dysfunction, left atrial (LA) dilation and mechanical failure develop, which frequently culminate in atrial fibrillation. Moreover, LA mechanical failure is accompanied by LA endocrine failure [deficient atrial natriuretic peptide ( ANP ) processing‐synthesis/development of ANP resistance) and LA regulatory failure (dominance of sympathetic nervous system excitatory mechanisms, excessive vasopressin release) contributing to neurohumoral overactivity, vasoconstriction, and volume overload (global LA failure). The purpose of the present review is to describe the characteristics and emphasize the clinical significance of global LA failure in patients with heart failure. |
| Author | Skoularigis, John Boudoulas, Harisios Triposkiadis, Filippos Butler, Javed Giamouzis, Gregory Brutsaert, Dirk Pieske, Burkert Parissis, John |
| Author_xml | – sequence: 1 givenname: Filippos surname: Triposkiadis fullname: Triposkiadis, Filippos email: ftriposkiadis@gmail.com, ftriposkiadis@gmail.com organization: Department of Cardiology, Larissa University Hospital, PO Box 1425, 411 10, Larissa, Greece – sequence: 2 givenname: Burkert surname: Pieske fullname: Pieske, Burkert organization: Department of Internal Medicine and Cardiology, Charité University Medicine Berlin-Campus Virchow Klinikum, and Department of Internal Medicine and Cardiology, German Heart Centre, Berlin Centre for Heart Failure, Berlin, Germany – sequence: 3 givenname: Javed surname: Butler fullname: Butler, Javed organization: Cardiology Division, School of Medicine, Stony Brook University, NY, Stony Brook, USA – sequence: 4 givenname: John surname: Parissis fullname: Parissis, John organization: Department of Cardiology, Athens University Hospital Attikon, Athens, Greece – sequence: 5 givenname: Gregory surname: Giamouzis fullname: Giamouzis, Gregory organization: Department of Cardiology, Larissa University Hospital, PO Box 1425, 411 10, Larissa, Greece – sequence: 6 givenname: John surname: Skoularigis fullname: Skoularigis, John organization: Department of Cardiology, Larissa University Hospital, PO Box 1425, 411 10, Larissa, Greece – sequence: 7 givenname: Dirk surname: Brutsaert fullname: Brutsaert, Dirk organization: Laboratory of Physiopharmacology (Building T2), University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium – sequence: 8 givenname: Harisios surname: Boudoulas fullname: Boudoulas, Harisios organization: Ohio State University, Columbus, Ohio, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27813305$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/j.cca.2011.10.032 10.1161/JAHA.112.005694 10.1093/europace/eus075 10.1152/ajpheart.00986.2005 10.1161/01.HYP.0000254322.96189.85 10.1161/CIRCULATIONAHA.112.001039 10.1007/s10741-007-9021-6 10.1016/j.ijcard.2015.07.028 10.1016/j.ijcard.2010.06.016 10.1161/CIRCEP.111.962720 10.1046/j.1365-2362.2003.01222.x 10.1016/S0140-6736(12)61227-6 10.1126/science.6538050 10.1161/HYPERTENSIONAHA.115.06300 10.1161/CIRCHEARTFAILURE.109.895581 10.1093/eurheartj/ehv132 10.1016/j.amjcard.2005.07.126 10.1148/rg.351130010 10.1007/s11906-015-0580-y 10.1093/oxfordjournals.eurheartj.a060251 10.1016/j.jacc.2007.09.026 10.1016/S0195-668X(03)00393-2 10.1161/CIRCHEARTFAILURE.113.000748 10.1093/eurheartj/ehm443 10.1016/0002-9149(92)90572-G 10.1016/j.echo.2006.08.013 10.1016/j.jjcc.2010.08.001 10.1056/NEJMoa1409077 10.1016/j.jacc.2004.09.054 10.1161/CIRCEP.110.959650 10.1016/j.ejheart.2004.01.005 10.1016/j.eupc.2004.04.006 10.1586/erc.12.110 10.1161/CIRCRESAHA.116.306082 10.1111/echo.13094 10.1161/CIRCULATIONAHA.109.873265 10.1002/ejhf.62 10.1161/01.ATV.zhq0504.7914 10.1016/S0735-1097(02)02305-7 10.1177/2048872615626355 10.1161/CIRCIMAGING.108.813071 10.1093/eurheartj/ehn361 10.1016/S0735-1097(00)00511-8 10.1016/S0140-6736(09)60040-4 10.1016/j.jchf.2014.10.011 10.1016/j.jchf.2015.03.015 10.1016/j.jjcc.2012.01.004 10.1097/HCO.0000000000000089 10.1016/j.tcm.2014.12.015 10.1161/CIRCRESAHA.115.306567 10.1136/hrt.2008.164145 10.1016/j.jcin.2015.02.014 10.1002/ejhf.147 10.1111/j.1540-8167.1999.tb00211.x 10.1093/ckj/sfu050 10.1161/CIRCHEARTFAILURE.114.001276 10.1016/j.aanat.2006.11.006 10.1093/eurheartj/ehr378 10.1152/physrev.00017.2002 10.1161/HYPERTENSIONAHA.112.193631 10.1016/j.pcad.2015.08.004 10.1016/j.jacc.2006.01.060 10.1016/j.jacc.2007.02.066 10.1152/jappl.1993.74.5.2225 10.1016/j.repc.2014.05.008 10.1053/euhj.1999.2581 10.1111/j.1476-5381.2012.01827.x 10.1016/j.jchf.2015.10.008 10.1093/ehjci/jeu165 10.1093/eurheartj/ehu405 10.1161/CIRCULATIONAHA.108.821306 10.1016/j.peptides.2014.06.011 10.1159/000360935 10.1586/17434440.2014.940315 10.1161/CIRCHEARTFAILURE.114.001667 10.1016/j.amjcard.2005.09.143 10.1161/CIRCRESAHA.115.301146 10.1089/ars.2013.5542 10.1136/heartjnl-2012-302007 10.1016/j.ijcard.2005.08.049 10.1161/CIRCHEARTFAILURE.113.000568 10.1016/S0002-9149(98)00452-4 10.1016/j.cardfail.2015.07.008 10.1016/j.jjcc.2011.01.002 10.1016/S1388-9842(01)00232-X 10.1016/j.hrthm.2014.01.033 10.1161/CIRCHEARTFAILURE.114.001174 10.1093/eurjhf/hfp112 10.1016/j.amjcard.2008.02.099 10.1016/j.jacc.2015.06.1313 10.1016/j.amjcard.2013.03.055 10.1016/j.jchf.2015.03.011 10.1016/j.ijcard.2013.05.028 10.1016/j.ijcard.2015.03.198 10.1161/CIRCULATIONAHA.114.010765 10.1002/ejhf.135 10.1093/eurheartj/ehv087 |
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| References | Hou Y, Scherlag BJ, Lin J, Zhang Y, Lu Z, Truong K, Patterson E, Lazzara R, Jackman WM, Po SS. Ganglionated plexi modulate extrinsic cardiac autonomic nerve input: effects on sinus rate, atrioventricular conduction, refractoriness, and inducibility of atrial fibrillation. J Am Coll Cardiol 2007;50:61-68. Rossi A, Gheorghiade M, Triposkiadis F, Solomon SD, Pieske B, Butler J. Left atrium in heart failure with preserved ejection fraction: Structure, function, and significance. Circ Heart Fail 2014;7:1042-1049. Casaclang-Verzosa G, Gersh BJ, Tsang TS. Structural and functional remodeling of the left atrium: clinical and therapeutic implications for atrial fibrillation. J Am Coll Cardiol 2008;51:1-11. Schirmer SH, Sayed MM, Reil JC, Lavall D, Ukena C, Linz D, Mahfoud F, Bohm M. Atrial remodeling following catheter-based renal denervation occurs in a blood pressure- and heart rate-independent manner. JACC Cardiovasc Interv 2015;8:972-980. Charloux A, Piquard F, Doutreleau S, Brandenberger G, Geny B. Mechanisms of renal hyporesponsiveness to ANP in heart failure. Eur J Clin Invest 2003;33:769-778. D'Andrea A, Caso P, Romano S, Scarafile R, Riegler L, Salerno G, Limongelli G, Di Salvo G, Calabro P, Del Viscovo L, Romano G, Maiello C, Santangelo L, Severino S, Cuomo S, Cotrufo M, Calabro R. Different effects of cardiac resynchronization therapy on left atrial function in patients with either idiopathic or ischaemic dilated cardiomyopathy: a two-dimensional speckle strain study. Eur Heart J 2007;28:2738-2748. Pieske B, Butler J, Filippatos G, Lam C, Maggioni AP, Ponikowski P, Shah S, Solomon S, Kraigher-Krainer E, Samano ET, Scalise AV, Muller K, Roessig L, Gheorghiade M. Rationale and design of the soluble guanylate cyclase stimulator in heart failure studies (SOCRATES). Eur J Heart Fail 2014;16:1026-1038. Bell V, Mitchell GF. Influence of vascular function and pulsatile hemodynamics on cardiac function. Curr Hypertens Rep 2015;17:580. van den Berg MP, Tjeerdsma G, Jan de Kam P, Boomsma F, Crijns HJ, van Veldhuisen DJ. Longstanding atrial fibrillation causes depletion of atrial natriuretic peptide in patients with advanced congestive heart failure. Eur J Heart Fail 2002;4:255-262. Ng J, Villuendas R, Cokic I, Schliamser JE, Gordon D, Koduri H, Benefield B, Simon J, Murthy SN, Lomasney JW, Wasserstrom JA, Goldberger JJ, Aistrup GL, Arora R. Autonomic remodeling in the left atrium and pulmonary veins in heart failure: creation of a dynamic substrate for atrial fibrillation. Circ Arrhythm Electrophysiol 2011;4:388-396. Shen X, Nair CK, Holmberg MJ, Mooss AN, Koruth J, Wang F, Maciejewski S, Esterbrooks DJ. Impact of left atrial volume in prediction of outcome after cardiac resynchronization therapy. Int J Cardiol 2011;152:13-17. Olsson LG, Swedberg K, Ducharme A, Granger CB, Michelson EL, McMurray JJ, Puu M, Yusuf S, Pfeffer MA; CHARM Investigators. Atrial fibrillation and risk of clinical events in chronic heart failure with and without left ventricular systolic dysfunction: results from the candesartan in heart failure-assessment of reduction in mortality and morbidity (CHARM) program. J Am Coll Cardiol 2006;47:1997-2004. Tsang TS, Barnes ME, Abhayaratna WP, Cha SS, Gersh BJ, Langins AP, Green TD, Bailey KR, Miyasaka Y, Seward JB. Effects of quinapril on left atrial structural remodeling and arterial stiffness. Am J Cardiol 2006;97:916-920. Davies SW, Fussell AL, Jordan SL, Poole-Wilson PA, Lipkin DP. Abnormal diastolic filling patterns in chronic heart failure - relationship to exercise capacity. Eur Heart J 1992;13:749-757. Jalife J, Kaur K. Atrial remodeling, fibrosis, and atrial fibrillation. Trends Cardiovasc Med 2015;25:475-484. Zakeri R, Borlaug BA, McNulty SE, Mohammed SF, Lewis GD, Semigran MJ, Deswal A, LeWinter M, Hernandez AF, Braunwald E, Redfield MM. Impact of atrial fibrillation on exercise capacity in heart failure with preserved ejection fraction: a RELAX trial ancillary study. Circ Heart Fail 2014;7:123-130. Ristow B, Ali S, Whooley MA, Schiller NB. Usefulness of left atrial volume index to predict heart failure hospitalization and mortality in ambulatory patients with coronary heart disease and comparison to left ventricular ejection fraction (from the Heart and Soul Study). Am J Cardiol 2008;102:70-76. Gottdiener JS, Kitzman DW, Aurigemma GP, Arnold AM, Manolio TA. Left atrial volume, geometry, and function in systolic and diastolic heart failure of persons ≥ 65 years of age (the Cardiovascular Health Study). Am J Cardiol 2006;97:83-89. Kusunose K, Motoki H, Popovic ZB, Thomas JD, Klein AL, Marwick TH. Independent association of left atrial function with exercise capacity in patients with preserved ejection fraction. Heart 2012;98:1311-1317. Dzeshka MS, Lip GY, Snezhitskiy V, Shantsila E. Cardiac fibrosis in patients with atrial fibrillation: mechanisms and clinical implications. J Am Coll Cardiol 2015;66:943-959. Kuperstein R, Goldenberg I, Moss AJ, Solomon S, Bourgoun M, Shah A, McNitt S, Zareba W, Klempfner R. Left atrial volume and the benefit of cardiac resynchronization therapy in the madit-crt trial. Circ Heart Fail 2014;7:154-160. Karayannis G, Kitsios G, Kotidis H, Triposkiadis F. Left atrial remodelling contributes to the progression of asymptomatic left ventricular systolic dysfunction to chronic symptomatic heart failure. Heart Fail Rev 2008;13:91-98. Pritchett AM, Mahoney DW, Jacobsen SJ, Rodeheffer RJ, Karon BL, Redfield MM. Diastolic dysfunction and left atrial volume: a population-based study. J Am Coll Cardiol 2005;45:87-92. Prabhu S, McLellan AJ, Walters TE, Sharma M, Voskoboinik A, Kistler PM. Atrial structure and function and its implications for current and emerging treatments for atrial fibrillation. Prog Cardiovasc Dis 2015;58:152-167. Kaneko H, Koike A, Senoo K, Tanaka S, Suzuki S, Nagayama O, Sagara K, Otsuka T, Matsuno S, Funada R, Uejima T, Oikawa Y, Yajima J, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Yamashita T. Role of cardiopulmonary dysfunction and left atrial remodeling in development of acute decompensated heart failure in chronic heart failure with preserved left ventricular ejection fraction. J Cardiol 2012;59:359-365. Vanoverschelde JJ, Essamri B, Vanbutsele R, d'Hondt A, Cosyns JR, Detry JR, Melin JA. Contribution of left ventricular diastolic function to exercise capacity in normal subjects. J Appl Physiol 1993;74:2225-2233. Tripathi R, Wang D, Sullivan R, Fan TH, Gladysheva IP, Reed GL. Depressed corin levels indicate early systolic dysfunction before increases of atrial natriuretic peptide/b-type natriuretic peptide and heart failure development. Hypertension 2016;67:362-367. Millar PJ, Murai H, Floras JS. Paradoxical muscle sympathetic reflex activation in human heart failure. Circulation 2015;131:459-468. McMurray JJ, Packer M, Desai AS, Gong J, Lefkowitz MP, Rizkala AR, Rouleau JL, Shi VC, Solomon SD, Swedberg K, Zile MR; PARADIGM-HF Investigators and Committees. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med 2014;371:993-1004. Stefanadis C, Dernellis J, Toutouzas P. A clinical appraisal of left atrial function. Eur Heart J 2001;22:22-36. Burkhoff D, Maurer MS, Joseph SM, Rogers JG, Birati EY, Rame JE, Shah SJ. Left atrial decompression pump for severe heart failure with preserved ejection fraction: theoretical and clinical considerations. JACC Heart Fail 2015;3:275-282. Bichet DG. Central vasopressin: dendritic and axonal secretion and renal actions. Clin Kidney J 2014;7:242-247. Huntley BK, Sandberg SM, Heublein DM, Sangaralingham SJ, Burnett JC Jr, Ichiki T. Pro-B-type natriuretic peptide-1-108 processing and degradation in human heart failure. Circ Heart Fail 2015;8:89-97. Triposkiadis F, Trikas A, Pitsavos C, Papadopoulos P, Toutouzas P. Relation of exercise capacity in dilated cardiomyopathy to left atrial size and systolic function. Am J Cardiol 1992;70:825-827. Grayburn PA, Foster E, Sangli C, Weissman NJ, Massaro J, Glower DG, Feldman T, Mauri L. Relationship between the magnitude of reduction in mitral regurgitation severity and left ventricular and left atrial reverse remodeling after MitraClip therapy. Circulation 2013;128:1667-1674. Agostoni P, Emdin M, Corra U, Veglia F, Magri D, Tedesco CC, Berton E, Passino C, Bertella E, Re F, Mezzani A, Belardinelli R, Colombo C, La Gioia R, Vicenzi M, Giannoni A, Scrutinio D, Giannuzzi P, Tondo C, Di Lenarda A, Sinagra G, Piepoli MF, Guazzi M. Permanent atrial fibrillation affects exercise capacity in chronic heart failure patients. Eur Heart J 2008;29:2367-2372. Stefan L, Sedlacek K, Cerna D, Kryze L, Vancura V, Marek T, Kautzner J. Small left atrium and mild mitral regurgitation predict super-response to cardiac resynchronization therapy. Europace 2012;14:1608-1614. Santos AB, Kraigher-Krainer E, Gupta DK, Claggett B, Zile MR, Pieske B, Voors AA, Lefkowitz M, Bransford T, Shi V, Packer M, McMurray JJ, Shah AM, Solomon SD. Impaired left atrial function in heart failure with preserved ejection fraction. Eur J Heart Fail 2014;16:1096-1103. Ibebuogu UN, Gladysheva IP, Houng AK, Reed GL. Decompensated heart failure is associated with reduced corin levels and decreased cleavage of pro-atrial natriuretic peptide. Circ Heart Fail 2011;4:114-120. Solomon SD, Zile M, Pieske B, Voors A, Shah A, Kraigher-Krainer E, Shi V, Bransford T, Takeuchi M, Gong J, Lefkowitz M, Packer M, McMurray JJ; Prospective comparison of ARNI with ARB on Management Of heart failUre with preserved ejectioN fracTion (PARAMOUNT) Investigators. The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial. Lancet 2012;380:1387-1395. Rossi A, Temporelli PL, Quintana M, Dini FL, Ghio S, Hillis GS, Klein AL, Marsan NA, Prior DL, Yu CM, Poppe KK, Doughty RN, Whalley GA; MeRGE Heart Failure Collaborators. Independent relationship of left atrial size and mortality in patients with heart failure: An individual patient meta-analysis of longitudinal data (MeR 2015; 35 2010; 56 2007; 189 2015; 36 2012; 166 2013; 2 2013; 61 2004; 24 2013; 128 2015; 187 2004; 6 2008; 35 2013; 168 2011; 57 1992; 13 2006; 291 2014; 371 2014; 29 1998; 82 2008; 102 2012; 59 2011; 152 2012; 14 2009; 119 2012; 10 2012; 98 2016; 33 2014; 20 2014; 129 2007; 28 2009; 11 2002; 40 2016; 118 2008; 29 2015; 131 1993; 74 2014; 16 2013; 112 2014; 58 1999; 10 2009; 120 2007; 20 2003; 83 2014; 7 2012; 413 2014; 11 2015; 58 2015; 17 2006; 97 2015; 16 2015; 3 1984; 223 2012; 380 2006; 110 2008; 13 2002; 4 2007; 50 2009; 373 2001; 22 2011; 4 2008; 51 2015; 8 2012; 33 2005; 45 2014; 115 2003; 33 2016; 4 2015; 25 1992; 70 2015; 116 2000; 35 2015; 199 2015; 66 2006; 47 2015; 21 2003; 24 2016 2009; 2 2012; 5 2010; 96 2014; 33 2016; 67 2007; 49 e_1_2_7_3_1 e_1_2_7_7_1 e_1_2_7_19_1 e_1_2_7_60_1 e_1_2_7_83_1 e_1_2_7_100_1 e_1_2_7_15_1 e_1_2_7_41_1 e_1_2_7_64_1 e_1_2_7_87_1 e_1_2_7_11_1 e_1_2_7_45_1 e_1_2_7_68_1 Acarturk E (e_1_2_7_66_1) 2008; 35 e_1_2_7_26_1 e_1_2_7_49_1 e_1_2_7_90_1 e_1_2_7_94_1 e_1_2_7_71_1 e_1_2_7_52_1 e_1_2_7_98_1 e_1_2_7_23_1 e_1_2_7_33_1 e_1_2_7_75_1 e_1_2_7_56_1 e_1_2_7_37_1 e_1_2_7_79_1 e_1_2_7_4_1 e_1_2_7_8_1 e_1_2_7_16_1 e_1_2_7_40_1 e_1_2_7_82_1 e_1_2_7_63_1 e_1_2_7_12_1 e_1_2_7_44_1 e_1_2_7_86_1 Tofield A. (e_1_2_7_96_1) 2015; 36 e_1_2_7_67_1 e_1_2_7_48_1 e_1_2_7_29_1 e_1_2_7_51_1 e_1_2_7_70_1 e_1_2_7_93_1 e_1_2_7_24_1 e_1_2_7_32_1 e_1_2_7_55_1 e_1_2_7_74_1 e_1_2_7_97_1 e_1_2_7_20_1 e_1_2_7_36_1 e_1_2_7_59_1 e_1_2_7_78_1 Boudoulas KD (e_1_2_7_5_1) 2014; 129 e_1_2_7_9_1 e_1_2_7_17_1 e_1_2_7_62_1 e_1_2_7_81_1 e_1_2_7_13_1 e_1_2_7_43_1 e_1_2_7_85_1 e_1_2_7_47_1 e_1_2_7_89_1 e_1_2_7_28_1 e_1_2_7_73_1 e_1_2_7_50_1 e_1_2_7_92_1 e_1_2_7_25_1 e_1_2_7_31_1 e_1_2_7_77_1 e_1_2_7_54_1 e_1_2_7_21_1 e_1_2_7_35_1 e_1_2_7_58_1 e_1_2_7_39_1 e_1_2_7_6_1 e_1_2_7_80_1 e_1_2_7_18_1 e_1_2_7_84_1 e_1_2_7_61_1 e_1_2_7_2_1 e_1_2_7_14_1 e_1_2_7_42_1 e_1_2_7_88_1 e_1_2_7_65_1 e_1_2_7_10_1 e_1_2_7_46_1 e_1_2_7_69_1 e_1_2_7_27_1 e_1_2_7_91_1 e_1_2_7_72_1 e_1_2_7_95_1 e_1_2_7_30_1 e_1_2_7_53_1 e_1_2_7_76_1 e_1_2_7_99_1 e_1_2_7_22_1 e_1_2_7_34_1 e_1_2_7_57_1 e_1_2_7_38_1 |
| References_xml | – reference: Melenovsky V, Hwang SJ, Redfield MM, Zakeri R, Lin G, Borlaug BA. Left atrial remodeling and function in advanced heart failure with preserved or reduced ejection fraction. Circ Heart Fail 2015;8:295-303. – reference: Lim SL, Lam CS, Segers VF, Brutsaert DL, De Keulenaer GW. Cardiac endothelium-myocyte interaction: clinical opportunities for new heart failure therapies regardless of ejection fraction. Eur Heart J 2015;36:2050-2060. – reference: Seward JB, Hebl VB. Left atrial anatomy and physiology: echo/Doppler assessment. Curr Opin Cardiol 2014;29:403-407. – reference: Gerdts E, Wachtell K, Omvik P, Otterstad JE, Oikarinen L, Boman K, Dahlof B, Devereux RB. Left atrial size and risk of major cardiovascular events during antihypertensive treatment: losartan intervention for endpoint reduction in hypertension trial. Hypertension 2007;49:311-316. – reference: Sanchis L, Gabrielli L, Andrea R, Falces C, Duchateau N, Perez-Villa F, Bijnens B, Sitges M. Left atrial dysfunction relates to symptom onset in patients with heart failure and preserved left ventricular ejection fraction. Eur Heart J Cardiovasc Imaging 2015;16:62-67. – reference: McManus DD, Hsu G, Sung SH, Saczynski JS, Smith DH, Magid DJ, Gurwitz JH, Goldberg RJ, Go AS, Cardiovascular Research Network PRESERVE Study. Atrial fibrillation and outcomes in heart failure with preserved versus reduced left ventricular ejection fraction. J Am Heart Assoc 2013;2:e005694. – reference: Alli O, Holmes D Jr. Evaluation of the Watchman left atrial appendage closure device. Exp Rev Med Device 2014;11:541-551. – reference: Masuda M, Yamada T, Mizuno H, Minamiguchi H, Konishi S, Ohtani T, Yamaguchi O, Okuyama Y, Uematsu M, Sakata Y. Impact of atrial fibrillation ablation on cardiac sympathetic nervous system in patients with and without heart failure. Int J Cardiol 2015;199:65-70. – reference: Chimoskey JE, Spielman WS, Brandt MA, Heidemann SR. Cardiac atria of bio 14.6 hamsters are deficient in natriuretic factor. Science 1984;223:820-822. – reference: Lopes C, Pereira T, Barra S. Cardiac resynchronization therapy in patients with atrial fibrillation: a meta-analysis. Rev Port Cardiol 2014;33:717-725. – reference: Gould PA, Esler MD, Kaye DM. Chronic atrial fibrillation does not influence the magnitude of sympathetic overactivity in patients with heart failure. Eur Heart J 2003;24:1657-1662. – reference: Ho SY, Cabrera JA, Sanchez-Quintana D. Left atrial anatomy revisited. Circ Arrhythm Electrophysiol 2012;5:220-228. – reference: Stefanadis C, Dernellis J, Toutouzas P. A clinical appraisal of left atrial function. Eur Heart J 2001;22:22-36. – reference: Owens AT, Brozena SC, Jessup M. New management strategies in heart failure. Circ Res 2016;118:480-495. – reference: Dahlstrom U. Can natriuretic peptides be used for the diagnosis of diastolic heart failure? Eur J Heart Fail 2004;6:281-287. – reference: Floras JS, Ponikowski P. The sympathetic/parasympathetic imbalance in heart failure with reduced ejection fraction. Eur Heart J 2015;36:1974-1982. – reference: Burkhoff D, Maurer MS, Joseph SM, Rogers JG, Birati EY, Rame JE, Shah SJ. Left atrial decompression pump for severe heart failure with preserved ejection fraction: theoretical and clinical considerations. JACC Heart Fail 2015;3:275-282. – reference: Kusunose K, Motoki H, Popovic ZB, Thomas JD, Klein AL, Marwick TH. Independent association of left atrial function with exercise capacity in patients with preserved ejection fraction. Heart 2012;98:1311-1317. – reference: Agostoni P, Emdin M, Corra U, Veglia F, Magri D, Tedesco CC, Berton E, Passino C, Bertella E, Re F, Mezzani A, Belardinelli R, Colombo C, La Gioia R, Vicenzi M, Giannoni A, Scrutinio D, Giannuzzi P, Tondo C, Di Lenarda A, Sinagra G, Piepoli MF, Guazzi M. Permanent atrial fibrillation affects exercise capacity in chronic heart failure patients. Eur Heart J 2008;29:2367-2372. – reference: Bell V, Mitchell GF. Influence of vascular function and pulsatile hemodynamics on cardiac function. Curr Hypertens Rep 2015;17:580. – reference: Vodovar N, Seronde MF, Laribi S, Gayat E, Lassus J, Januzzi JL Jr, Boukef R, Nouira S, Manivet P, Samuel JL, Logeart D, Cohen-Solal A, Richards AM, Launay JM, Mebazaa A, Network G. Elevated plasma b-type natriuretic peptide concentrations directly inhibit circulating neprilysin activity in heart failure. JACC Heart Fail 2015;3:629-636. – reference: Kaneko H, Koike A, Senoo K, Tanaka S, Suzuki S, Nagayama O, Sagara K, Otsuka T, Matsuno S, Funada R, Uejima T, Oikawa Y, Yajima J, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Yamashita T. Role of cardiopulmonary dysfunction and left atrial remodeling in development of acute decompensated heart failure in chronic heart failure with preserved left ventricular ejection fraction. J Cardiol 2012;59:359-365. – reference: Anter E, Jessup M, Callans DJ. Atrial fibrillation and heart failure: treatment considerations for a dual epidemic. Circulation 2009;119:2516-2525. – reference: Grayburn PA, Foster E, Sangli C, Weissman NJ, Massaro J, Glower DG, Feldman T, Mauri L. Relationship between the magnitude of reduction in mitral regurgitation severity and left ventricular and left atrial reverse remodeling after MitraClip therapy. Circulation 2013;128:1667-1674. – reference: Gladysheva IP, Wang D, McNamee RA, Houng AK, Mohamad AA, Fan TM, Reed GL. Corin overexpression improves cardiac function, heart failure, and survival in mice with dilated cardiomyopathy. Hypertension 2013;61:327-332. – reference: Ng J, Villuendas R, Cokic I, Schliamser JE, Gordon D, Koduri H, Benefield B, Simon J, Murthy SN, Lomasney JW, Wasserstrom JA, Goldberger JJ, Aistrup GL, Arora R. Autonomic remodeling in the left atrium and pulmonary veins in heart failure: creation of a dynamic substrate for atrial fibrillation. Circ Arrhythm Electrophysiol 2011;4:388-396. – reference: Schmitt M, Gunaruwan P, Payne N, Taylor J, Lee L, Broadley AJ, Nightingale AK, Cockcroft JR, Struthers AD, Tyberg JV, Frenneaux MP. Effects of exogenous and endogenous natriuretic peptides on forearm vascular function in chronic heart failure. Arterioscler Thromb Vasc Biol 2004;24:911-917. – reference: van den Berg MP, van Gelder IC, van Veldhuisen DJ. Depletion of atrial natriuretic peptide during longstanding atrial fibrillation. Europace 2004;6:433-437. – reference: Ho SY, Sanchez-Quintana D, Cabrera JA, Anderson RH. Anatomy of the left atrium: implications for radiofrequency ablation of atrial fibrillation. J Cardiovasc Electrophysiol 1999;10:1525-1533. – reference: Prioli A, Marino P, Lanzoni L, Zardini P. Increasing degrees of left ventricular filling impairment modulate left atrial function in humans. Am J Cardiol 1998;82:756-761. – reference: Saito Y. Roles of atrial natriuretic peptide and its therapeutic use. J Cardiol 2010;56:262-270. – reference: Nishikimi T, Kuwahara K, Nakao K. Current biochemistry, molecular biology, and clinical relevance of natriuretic peptides. J Cardiol 2011;57:131-140. – reference: Solomon SD, Zile M, Pieske B, Voors A, Shah A, Kraigher-Krainer E, Shi V, Bransford T, Takeuchi M, Gong J, Lefkowitz M, Packer M, McMurray JJ; Prospective comparison of ARNI with ARB on Management Of heart failUre with preserved ejectioN fracTion (PARAMOUNT) Investigators. The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial. Lancet 2012;380:1387-1395. – reference: McMurray JJ, Packer M, Desai AS, Gong J, Lefkowitz MP, Rizkala AR, Rouleau JL, Shi VC, Solomon SD, Swedberg K, Zile MR; PARADIGM-HF Investigators and Committees. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med 2014;371:993-1004. – reference: Jalife J, Kaur K. Atrial remodeling, fibrosis, and atrial fibrillation. Trends Cardiovasc Med 2015;25:475-484. – reference: Slyngstad T, Huth Ruwald AC, Kutyifa V, McNitt S, Polonsky B, Solomon SD, Foster E, Goldenberg I, Wang PJ, Klein H, Zareba W, Moss AJ. Cardiac resynchronization therapy is associated with reductions in left atrial volume and inappropriate implantable cardioverter-defibrillator therapy in MADIT-CRT. Heart Rhythm 2014;11:1001-1007. – reference: Zakeri R, Borlaug BA, McNulty SE, Mohammed SF, Lewis GD, Semigran MJ, Deswal A, LeWinter M, Hernandez AF, Braunwald E, Redfield MM. Impact of atrial fibrillation on exercise capacity in heart failure with preserved ejection fraction: a RELAX trial ancillary study. Circ Heart Fail 2014;7:123-130. – reference: Hou Y, Scherlag BJ, Lin J, Zhang Y, Lu Z, Truong K, Patterson E, Lazzara R, Jackman WM, Po SS. Ganglionated plexi modulate extrinsic cardiac autonomic nerve input: effects on sinus rate, atrioventricular conduction, refractoriness, and inducibility of atrial fibrillation. J Am Coll Cardiol 2007;50:61-68. – reference: D'Andrea A, Caso P, Romano S, Scarafile R, Riegler L, Salerno G, Limongelli G, Di Salvo G, Calabro P, Del Viscovo L, Romano G, Maiello C, Santangelo L, Severino S, Cuomo S, Cotrufo M, Calabro R. Different effects of cardiac resynchronization therapy on left atrial function in patients with either idiopathic or ischaemic dilated cardiomyopathy: a two-dimensional speckle strain study. Eur Heart J 2007;28:2738-2748. – reference: Triposkiadis F, Harbas C, Kelepeshis G, Sitafidis G, Skoularigis J, Demopoulos V, Tsilimingas N. Left atrial remodeling in patients younger than 70 years with diastolic and systolic heart failure. J Am Soc Echocardiogr 2007;20:177-185. – reference: Guazzi M, Belletti S, Bianco E, Lenatti L, Guazzi MD. Endothelial dysfunction and exercise performance in lone atrial fibrillation or associated with hypertension or diabetes: different results with cardioversion. Am J Physiol Heart Circ Physiol 2006;291:H921-H928. – reference: Rossi A, Gheorghiade M, Triposkiadis F, Solomon SD, Pieske B, Butler J. Left atrium in heart failure with preserved ejection fraction: Structure, function, and significance. Circ Heart Fail 2014;7:1042-1049. – reference: Pinho-Gomes AC, Reilly S, Brandes RP, Casadei B. Targeting inflammation and oxidative stress in atrial fibrillation: role of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibition with statins. Antioxid Redox Signal 2014;20:1268-1285. – reference: Millar PJ, Murai H, Floras JS. Paradoxical muscle sympathetic reflex activation in human heart failure. Circulation 2015;131:459-468. – reference: Xu-Cai YO, Wu Q. Molecular forms of natriuretic peptides in heart failure and their implications. Heart 2010;96:419-424. – reference: Shen X, Nair CK, Holmberg MJ, Mooss AN, Koruth J, Wang F, Maciejewski S, Esterbrooks DJ. Impact of left atrial volume in prediction of outcome after cardiac resynchronization therapy. Int J Cardiol 2011;152:13-17. – reference: Schirmer SH, Sayed MM, Reil JC, Lavall D, Ukena C, Linz D, Mahfoud F, Bohm M. Atrial remodeling following catheter-based renal denervation occurs in a blood pressure- and heart rate-independent manner. JACC Cardiovasc Interv 2015;8:972-980. – reference: Brutsaert DL. Cardiac endothelial-myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicity. Physiol Rev 2003;83:59-115. – reference: Boudoulas KD, Paraskevaidis IA, Boudoulas H, Triposkiadis FK. The left atrium: From the research laboratory to the clinic. Cardiology 2014;129:1-17. – reference: Lai YC, Potoka KC, Champion HC, Mora AL, Gladwin MT. Pulmonary arterial hypertension: the clinical syndrome. Circ Res 2014;115:115-130. – reference: Tarone G, Balligand JL, Bauersachs J, Clerk A, De Windt L, Heymans S, Hilfiker-Kleiner D, Hirsch E, Iaccarino G, Knoll R, Leite-Moreira AF, Lourenco AP, Mayr M, Thum T, Tocchetti CG. Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology. Eur J Heart Fail 2014;16:494-508. – reference: Rossi A, Temporelli PL, Quintana M, Dini FL, Ghio S, Hillis GS, Klein AL, Marsan NA, Prior DL, Yu CM, Poppe KK, Doughty RN, Whalley GA; MeRGE Heart Failure Collaborators. Independent relationship of left atrial size and mortality in patients with heart failure: An individual patient meta-analysis of longitudinal data (MeRGE Heart Failure). Eur J Heart Fail 2009;11:929-936. – reference: Charloux A, Piquard F, Doutreleau S, Brandenberger G, Geny B. Mechanisms of renal hyporesponsiveness to ANP in heart failure. Eur J Clin Invest 2003;33:769-778. – reference: Vanoverschelde JJ, Essamri B, Vanbutsele R, d'Hondt A, Cosyns JR, Detry JR, Melin JA. Contribution of left ventricular diastolic function to exercise capacity in normal subjects. J Appl Physiol 1993;74:2225-2233. – reference: Pieske B, Butler J, Filippatos G, Lam C, Maggioni AP, Ponikowski P, Shah S, Solomon S, Kraigher-Krainer E, Samano ET, Scalise AV, Muller K, Roessig L, Gheorghiade M. Rationale and design of the soluble guanylate cyclase stimulator in heart failure studies (SOCRATES). Eur J Heart Fail 2014;16:1026-1038. – reference: Gama EF, de Carvalho CA, Liberti EA, de Souza RR. Atrial natriuretic peptide (ANP)-granules in the guinea pig atrial and auricular cardiocytes: an immunocytochemical and ultrastructural morphometric comparative study. Ann Anat 2007;189:457-464. – reference: Karayannis G, Kitsios G, Kotidis H, Triposkiadis F. Left atrial remodelling contributes to the progression of asymptomatic left ventricular systolic dysfunction to chronic symptomatic heart failure. Heart Fail Rev 2008;13:91-98. – reference: Mair J, Lindahl B, Giannitsis E, Huber K, Thygesen K, Plebani M, Mockel M, Muller C, Jaffe AS; Biomarker Study Group of the European Society of Cardiology Acute Cardiovascular Care Association. Will sacubitril-valsartan diminish the clinical utility of B-type natriuretic peptide testing in acute cardiac care? Eur Heart J Acute Cardiovasc Care 2016; doi: 10.1177/2048872615626355. – reference: Arrigo M, Huber LC. Eponyms in cardiopulmonary reflexes. Am J Cardiol 2013;112:449-453. – reference: Dzeshka MS, Lip GY, Snezhitskiy V, Shantsila E. Cardiac fibrosis in patients with atrial fibrillation: mechanisms and clinical implications. J Am Coll Cardiol 2015;66:943-959. – reference: Tofield A. Recurrent atrial fibrillation reduced after renal denervation with pulmonary vein ablation in select patients. Eur Heart J 2015;36:257. – reference: Kurt M, Wang J, Torre-Amione G, Nagueh SF. Left atrial function in diastolic heart failure. Circ Cardiovasc Imaging 2009;2:10-15. – reference: Tripathi R, Wang D, Sullivan R, Fan TH, Gladysheva IP, Reed GL. Depressed corin levels indicate early systolic dysfunction before increases of atrial natriuretic peptide/b-type natriuretic peptide and heart failure development. Hypertension 2016;67:362-367. – reference: Casaclang-Verzosa G, Gersh BJ, Tsang TS. Structural and functional remodeling of the left atrium: clinical and therapeutic implications for atrial fibrillation. J Am Coll Cardiol 2008;51:1-11. – reference: Pellicori P, Zhang J, Lukaschuk E, Joseph AC, Bourantas CV, Loh H, Bragadeesh T, Clark AL, Cleland JG. Left atrial function measured by cardiac magnetic resonance imaging in patients with heart failure: clinical associations and prognostic value. Eur Heart J 2015;36:733-742. – reference: Ibebuogu UN, Gladysheva IP, Houng AK, Reed GL. Decompensated heart failure is associated with reduced corin levels and decreased cleavage of pro-atrial natriuretic peptide. Circ Heart Fail 2011;4:114-120. – reference: Ristow B, Ali S, Whooley MA, Schiller NB. Usefulness of left atrial volume index to predict heart failure hospitalization and mortality in ambulatory patients with coronary heart disease and comparison to left ventricular ejection fraction (from the Heart and Soul Study). Am J Cardiol 2008;102:70-76. – reference: Prabhu S, McLellan AJ, Walters TE, Sharma M, Voskoboinik A, Kistler PM. Atrial structure and function and its implications for current and emerging treatments for atrial fibrillation. Prog Cardiovasc Dis 2015;58:152-167. – reference: Bichet DG. Central vasopressin: dendritic and axonal secretion and renal actions. Clin Kidney J 2014;7:242-247. – reference: Cameli M, Sparla S, Losito M, Righini FM, Menci D, Lisi M, D'Ascenzi F, Focardi M, Favilli R, Pierli C, Fineschi M, Mondillo S. Correlation of left atrial strain and Doppler measurements with invasive measurement of left ventricular end-diastolic pressure in patients stratified for different values of ejection fraction. Echocardiography 2016;33:398-405. – reference: Rossi A, Cicoira M, Florea VG, Golia G, Florea ND, Khan AA, Murray ST, Nguyen JT, O'Callaghan P, Anand IS, Coats A, Zardini P, Vassanelli C, Henein M. Chronic heart failure with preserved left ventricular ejection fraction: diagnostic and prognostic value of left atrial size. Int J Cardiol. 2006;110:386-392. – reference: Huntley BK, Sandberg SM, Heublein DM, Sangaralingham SJ, Burnett JC Jr, Ichiki T. Pro-B-type natriuretic peptide-1-108 processing and degradation in human heart failure. Circ Heart Fail 2015;8:89-97. – reference: Fabbri G, Maggioni AP. A review of the epidemiological profile of patients with atrial fibrillation and heart failure. Exp Rev Cardiovasc Ther 2012;10:1133-1140. – reference: Ichiki T, Huntley BK, Sangaralingham SJ, Burnett JC Jr. Pro-atrial natriuretic peptide: a novel guanylyl cyclase-a receptor activator that goes beyond atrial and B-type natriuretic peptides. JACC Heart Fail 2015;3:715-723. – reference: Santos AB, Kraigher-Krainer E, Gupta DK, Claggett B, Zile MR, Pieske B, Voors AA, Lefkowitz M, Bransford T, Shi V, Packer M, McMurray JJ, Shah AM, Solomon SD. Impaired left atrial function in heart failure with preserved ejection fraction. Eur J Heart Fail 2014;16:1096-1103. – reference: Rosenberg MA, Gottdiener JS, Heckbert SR, Mukamal KJ. Echocardiographic diastolic parameters and risk of atrial fibrillation: the Cardiovascular Health Study. Eur Heart J 2012;33:904-912. – reference: Davies SW, Fussell AL, Jordan SL, Poole-Wilson PA, Lipkin DP. Abnormal diastolic filling patterns in chronic heart failure - relationship to exercise capacity. Eur Heart J 1992;13:749-757. – reference: Quinones MA, Greenberg BH, Kopelen HA, Koilpillai C, Limacher MC, Shindler DM, Shelton BJ, Weiner DH. Echocardiographic predictors of clinical outcome in patients with left ventricular dysfunction enrolled in the SOLVD registry and trials: significance of left ventricular hypertrophy. Studies of Left Ventricular Dysfunction. J Am Coll Cardiol 2000;35:1237-1244. – reference: Malik SB, Kwan D, Shah AB, Hsu JY. The right atrium: Gateway to the heart - anatomic and pathologic imaging findings. Radiographics 2015;35:14-31. – reference: Stefan L, Sedlacek K, Cerna D, Kryze L, Vancura V, Marek T, Kautzner J. Small left atrium and mild mitral regurgitation predict super-response to cardiac resynchronization therapy. Europace 2012;14:1608-1614. – reference: Buggey J, Mentz RJ, DeVore AD, Velazquez EJ. Angiotensin receptor neprilysin inhibition in heart failure: mechanistic action and clinical impact. J Card Fail 2015;21:741-750. – reference: Patton KK, Ellinor PT, Heckbert SR, Christenson RH, DeFilippi C, Gottdiener JS, Kronmal RA. N-terminal pro-B-type natriuretic peptide is a major predictor of the development of atrial fibrillation: the Cardiovascular Health Study. Circulation 2009;120:1768-1774. – reference: Rossi L, Malagoli A, Piepoli M, Franchi F, Malavasi V, Casali E, Rusticali G, Villani GQ. Indexed maximal left atrial volume predicts response to cardiac resynchronization therapy. Int J Cardiol 2013;168:3629-3633. – reference: Olsson LG, Swedberg K, Ducharme A, Granger CB, Michelson EL, McMurray JJ, Puu M, Yusuf S, Pfeffer MA; CHARM Investigators. Atrial fibrillation and risk of clinical events in chronic heart failure with and without left ventricular systolic dysfunction: results from the candesartan in heart failure-assessment of reduction in mortality and morbidity (CHARM) program. J Am Coll Cardiol 2006;47:1997-2004. – reference: Kuhn M. Endothelial actions of atrial and B-type natriuretic peptides. Br J Pharmacol 2012;166:522-531. – reference: Dong N, Chen S, Wang W, Zhou Y, Wu Q. Corin in clinical laboratory diagnostics. Clin Chim Acta 2012;413:378-383. – reference: Gottdiener JS, Kitzman DW, Aurigemma GP, Arnold AM, Manolio TA. Left atrial volume, geometry, and function in systolic and diastolic heart failure of persons ≥ 65 years of age (the Cardiovascular Health Study). Am J Cardiol 2006;97:83-89. – reference: Edelmann F, Musial-Bright L, Gelbrich G, Trippel T, Radenovic S, Wachter R, Inkrot S, Loncar G, Tahirovic E, Celic V, Veskovic J, Zdravkovic M, Lainscak M, Apostolović S, Neskovic AN, Pieske B, Düngen HD; CIBIS-ELD Investigators and Project Multicenter Trials in the Competence Network Heart Failure. Tolerability and feasibility of beta-blocker titration in HFpEF versus HFrEF: insights from the CIBIS-ELD trial. JACC Heart Fail 2016;4:140-149. – reference: Perera RK, Sprenger JU, Steinbrecher JH, Hubscher D, Lehnart SE, Abesser M, Schuh K, El-Armouche A, Nikolaev VO. Microdomain switch of cGMP-regulated phosphodiesterases leads to ANP-induced augmentation of beta-adrenoceptor-stimulated contractility in early cardiac hypertrophy. Circ Res 2015;116:1304-1311. – reference: Malek F, Neuzil P, Gustafsson F, Kaye DM, Walton A, Mates M, Sondergaard L, Ihlemann N, Mariani JA, Reddy V. Clinical outcome of transcatheter treatment of heart failure with preserved or mildly reduced ejection fraction using a novel implant. Int J Cardiol 2015;187:227-228. – reference: Tsang TS, Barnes ME, Abhayaratna WP, Cha SS, Gersh BJ, Langins AP, Green TD, Bailey KR, Miyasaka Y, Seward JB. Effects of quinapril on left atrial structural remodeling and arterial stiffness. Am J Cardiol 2006;97:916-920. – reference: Kuperstein R, Goldenberg I, Moss AJ, Solomon S, Bourgoun M, Shah A, McNitt S, Zareba W, Klempfner R. Left atrial volume and the benefit of cardiac resynchronization therapy in the madit-crt trial. Circ Heart Fail 2014;7:154-160. – reference: Triposkiadis F, Trikas A, Pitsavos C, Papadopoulos P, Toutouzas P. Relation of exercise capacity in dilated cardiomyopathy to left atrial size and systolic function. Am J Cardiol 1992;70:825-827. – reference: Pritchett AM, Mahoney DW, Jacobsen SJ, Rodeheffer RJ, Karon BL, Redfield MM. Diastolic dysfunction and left atrial volume: a population-based study. J Am Coll Cardiol 2005;45:87-92. – reference: van den Berg MP, Tjeerdsma G, Jan de Kam P, Boomsma F, Crijns HJ, van Veldhuisen DJ. Longstanding atrial fibrillation causes depletion of atrial natriuretic peptide in patients with advanced congestive heart failure. Eur J Heart Fail 2002;4:255-262. – reference: Acarturk E, Koc M, Bozkurt A, Unal I. Left atrial size may predict exercise capacity and cardiovascular events in patients with heart failure. Tex Heart Inst J 2008;35:136-143. – reference: Rossi A, Cicoira M, Zanolla L, Sandrini R, Golia G, Zardini P, Enriquez-Sarano M. Determinants and prognostic value of left atrial volume in patients with dilated cardiomyopathy. J Am Coll Cardiol 2002;40:1425. – reference: De Vito P. Atrial natriuretic peptide: an old hormone or a new cytokine? Peptides 2014;58:108-116. – reference: Watson T, Shantsila E, Lip GY. Mechanisms of thrombogenesis in atrial fibrillation: Virchow's triad revisited. Lancet 2009;373:155-166. – volume: 97 start-page: 83 year: 2006 end-page: 89 article-title: Left atrial volume, geometry, and function in systolic and diastolic heart failure of persons ≥ 65 years of age (the Cardiovascular Health Study) publication-title: Am J Cardiol – volume: 16 start-page: 1096 year: 2014 end-page: 1103 article-title: Impaired left atrial function in heart failure with preserved ejection fraction publication-title: Eur J Heart Fail – volume: 16 start-page: 62 year: 2015 end-page: 67 article-title: Left atrial dysfunction relates to symptom onset in patients with heart failure and preserved left ventricular ejection fraction publication-title: Eur Heart J Cardiovasc Imaging – volume: 36 start-page: 257 year: 2015 article-title: Recurrent atrial fibrillation reduced after renal denervation with pulmonary vein ablation in select patients publication-title: Eur Heart J – volume: 152 start-page: 13 year: 2011 end-page: 17 article-title: Impact of left atrial volume in prediction of outcome after cardiac resynchronization therapy publication-title: Int J Cardiol – volume: 413 start-page: 378 year: 2012 end-page: 383 article-title: Corin in clinical laboratory diagnostics publication-title: Clin Chim Acta – volume: 35 start-page: 14 year: 2015 end-page: 31 article-title: The right atrium: Gateway to the heart – anatomic and pathologic imaging findings publication-title: Radiographics – volume: 112 start-page: 449 year: 2013 end-page: 453 article-title: Eponyms in cardiopulmonary reflexes publication-title: Am J Cardiol – volume: 7 start-page: 242 year: 2014 end-page: 247 article-title: Central vasopressin: dendritic and axonal secretion and renal actions publication-title: Clin Kidney J – volume: 58 start-page: 152 year: 2015 end-page: 167 article-title: Atrial structure and function and its implications for current and emerging treatments for atrial fibrillation publication-title: Prog Cardiovasc Dis – volume: 2 start-page: 10 year: 2009 end-page: 15 article-title: Left atrial function in diastolic heart failure publication-title: Circ Cardiovasc Imaging – volume: 2 year: 2013 article-title: Cardiovascular Research Network PRESERVE Study. Atrial fibrillation and outcomes in heart failure with preserved versus reduced left ventricular ejection fraction publication-title: J Am Heart Assoc – volume: 129 start-page: 1 year: 2014 end-page: 17 article-title: The left atrium: From the research laboratory to the clinic publication-title: Cardiology – volume: 67 start-page: 362 year: 2016 end-page: 367 article-title: Depressed corin levels indicate early systolic dysfunction before increases of atrial natriuretic peptide/b‐type natriuretic peptide and heart failure development publication-title: Hypertension – volume: 33 start-page: 398 year: 2016 end-page: 405 article-title: Correlation of left atrial strain and Doppler measurements with invasive measurement of left ventricular end‐diastolic pressure in patients stratified for different values of ejection fraction publication-title: Echocardiography – volume: 8 start-page: 972 year: 2015 end-page: 980 article-title: Atrial remodeling following catheter‐based renal denervation occurs in a blood pressure‐ and heart rate‐independent manner publication-title: JACC Cardiovasc Interv – volume: 199 start-page: 65 year: 2015 end-page: 70 article-title: Impact of atrial fibrillation ablation on cardiac sympathetic nervous system in patients with and without heart failure publication-title: Int J Cardiol – volume: 50 start-page: 61 year: 2007 end-page: 68 article-title: Ganglionated plexi modulate extrinsic cardiac autonomic nerve input: effects on sinus rate, atrioventricular conduction, refractoriness, and inducibility of atrial fibrillation publication-title: J Am Coll Cardiol – volume: 66 start-page: 943 year: 2015 end-page: 959 article-title: Cardiac fibrosis in patients with atrial fibrillation: mechanisms and clinical implications publication-title: J Am Coll Cardiol – volume: 116 start-page: 1304 year: 2015 end-page: 1311 article-title: Microdomain switch of cGMP‐regulated phosphodiesterases leads to ANP‐induced augmentation of beta‐adrenoceptor‐stimulated contractility in early cardiac hypertrophy publication-title: Circ Res – volume: 61 start-page: 327 year: 2013 end-page: 332 article-title: Corin overexpression improves cardiac function, heart failure, and survival in mice with dilated cardiomyopathy publication-title: Hypertension – year: 2016 article-title: Biomarker Study Group of the European Society of Cardiology Acute Cardiovascular Care Association. Will sacubitril‐valsartan diminish the clinical utility of B‐type natriuretic peptide testing in acute cardiac care? publication-title: Eur Heart J Acute Cardiovasc Care – volume: 371 start-page: 993 year: 2014 end-page: 1004 article-title: Angiotensin‐neprilysin inhibition versus enalapril in heart failure publication-title: N Engl J Med – volume: 291 start-page: H921 year: 2006 end-page: H928 article-title: Endothelial dysfunction and exercise performance in lone atrial fibrillation or associated with hypertension or diabetes: different results with cardioversion publication-title: Am J Physiol Heart Circ Physiol – volume: 373 start-page: 155 year: 2009 end-page: 166 article-title: Mechanisms of thrombogenesis in atrial fibrillation: Virchow's triad revisited publication-title: Lancet – volume: 96 start-page: 419 year: 2010 end-page: 424 article-title: Molecular forms of natriuretic peptides in heart failure and their implications publication-title: Heart – volume: 24 start-page: 911 year: 2004 end-page: 917 article-title: Effects of exogenous and endogenous natriuretic peptides on forearm vascular function in chronic heart failure publication-title: Arterioscler Thromb Vasc Biol – volume: 98 start-page: 1311 year: 2012 end-page: 1317 article-title: Independent association of left atrial function with exercise capacity in patients with preserved ejection fraction publication-title: Heart – volume: 21 start-page: 741 year: 2015 end-page: 750 article-title: Angiotensin receptor neprilysin inhibition in heart failure: mechanistic action and clinical impact publication-title: J Card Fail – volume: 3 start-page: 715 year: 2015 end-page: 723 article-title: Pro‐atrial natriuretic peptide: a novel guanylyl cyclase‐a receptor activator that goes beyond atrial and B‐type natriuretic peptides publication-title: JACC Heart Fail – volume: 187 start-page: 227 year: 2015 end-page: 228 article-title: Clinical outcome of transcatheter treatment of heart failure with preserved or mildly reduced ejection fraction using a novel implant publication-title: Int J Cardiol – volume: 56 start-page: 262 year: 2010 end-page: 270 article-title: Roles of atrial natriuretic peptide and its therapeutic use publication-title: J Cardiol – volume: 35 start-page: 136 year: 2008 end-page: 143 article-title: Left atrial size may predict exercise capacity and cardiovascular events in patients with heart failure publication-title: Tex Heart Inst J – volume: 36 start-page: 2050 year: 2015 end-page: 2060 article-title: Cardiac endothelium–myocyte interaction: clinical opportunities for new heart failure therapies regardless of ejection fraction publication-title: Eur Heart J – volume: 33 start-page: 717 year: 2014 end-page: 725 article-title: Cardiac resynchronization therapy in patients with atrial fibrillation: a meta‐analysis publication-title: Rev Port Cardiol – volume: 5 start-page: 220 year: 2012 end-page: 228 article-title: Left atrial anatomy revisited publication-title: Circ Arrhythm Electrophysiol – volume: 118 start-page: 480 year: 2016 end-page: 495 article-title: New management strategies in heart failure publication-title: Circ Res – volume: 168 start-page: 3629 year: 2013 end-page: 3633 article-title: Indexed maximal left atrial volume predicts response to cardiac resynchronization therapy publication-title: Int J Cardiol – volume: 4 start-page: 140 year: 2016 end-page: 149 article-title: Tolerability and feasibility of beta‐blocker titration in HFpEF versus HFrEF: insights from the CIBIS‐ELD trial publication-title: JACC Heart Fail – volume: 223 start-page: 820 year: 1984 end-page: 822 article-title: Cardiac atria of bio 14.6 hamsters are deficient in natriuretic factor publication-title: Science – volume: 57 start-page: 131 year: 2011 end-page: 140 article-title: Current biochemistry, molecular biology, and clinical relevance of natriuretic peptides publication-title: J Cardiol – volume: 102 start-page: 70 year: 2008 end-page: 76 article-title: Usefulness of left atrial volume index to predict heart failure hospitalization and mortality in ambulatory patients with coronary heart disease and comparison to left ventricular ejection fraction (from the Heart and Soul Study) publication-title: Am J Cardiol – volume: 189 start-page: 457 year: 2007 end-page: 464 article-title: Atrial natriuretic peptide (ANP)‐granules in the guinea pig atrial and auricular cardiocytes: an immunocytochemical and ultrastructural morphometric comparative study publication-title: Ann Anat – volume: 59 start-page: 359 year: 2012 end-page: 365 article-title: Role of cardiopulmonary dysfunction and left atrial remodeling in development of acute decompensated heart failure in chronic heart failure with preserved left ventricular ejection fraction publication-title: J Cardiol – volume: 10 start-page: 1525 year: 1999 end-page: 1533 article-title: Anatomy of the left atrium: implications for radiofrequency ablation of atrial fibrillation publication-title: J Cardiovasc Electrophysiol – volume: 6 start-page: 433 year: 2004 end-page: 437 article-title: Depletion of atrial natriuretic peptide during longstanding atrial fibrillation publication-title: Europace – volume: 3 start-page: 275 year: 2015 end-page: 282 article-title: Left atrial decompression pump for severe heart failure with preserved ejection fraction: theoretical and clinical considerations publication-title: JACC Heart Fail – volume: 128 start-page: 1667 year: 2013 end-page: 1674 article-title: Relationship between the magnitude of reduction in mitral regurgitation severity and left ventricular and left atrial reverse remodeling after MitraClip therapy publication-title: Circulation – volume: 7 start-page: 154 year: 2014 end-page: 160 article-title: Left atrial volume and the benefit of cardiac resynchronization therapy in the madit‐crt trial publication-title: Circ Heart Fail – volume: 20 start-page: 177 year: 2007 end-page: 185 article-title: Left atrial remodeling in patients younger than 70 years with diastolic and systolic heart failure publication-title: J Am Soc Echocardiogr – volume: 380 start-page: 1387 year: 2012 end-page: 1395 article-title: The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double‐blind randomised controlled trial publication-title: Lancet – volume: 83 start-page: 59 year: 2003 end-page: 115 article-title: Cardiac endothelial‐myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicity publication-title: Physiol Rev – volume: 49 start-page: 311 year: 2007 end-page: 316 article-title: Left atrial size and risk of major cardiovascular events during antihypertensive treatment: losartan intervention for endpoint reduction in hypertension trial publication-title: Hypertension – volume: 51 start-page: 1 year: 2008 end-page: 11 article-title: Structural and functional remodeling of the left atrium: clinical and therapeutic implications for atrial fibrillation publication-title: J Am Coll Cardiol – volume: 20 start-page: 1268 year: 2014 end-page: 1285 article-title: Targeting inflammation and oxidative stress in atrial fibrillation: role of 3‐hydroxy‐3‐methylglutaryl‐coenzyme a reductase inhibition with statins publication-title: Antioxid Redox Signal – volume: 97 start-page: 916 year: 2006 end-page: 920 article-title: Effects of quinapril on left atrial structural remodeling and arterial stiffness publication-title: Am J Cardiol – volume: 45 start-page: 87 year: 2005 end-page: 92 article-title: Diastolic dysfunction and left atrial volume: a population‐based study publication-title: J Am Coll Cardiol – volume: 6 start-page: 281 year: 2004 end-page: 287 article-title: Can natriuretic peptides be used for the diagnosis of diastolic heart failure? publication-title: Eur J Heart Fail – volume: 11 start-page: 1001 year: 2014 end-page: 1007 article-title: Cardiac resynchronization therapy is associated with reductions in left atrial volume and inappropriate implantable cardioverter‐defibrillator therapy in MADIT‐CRT publication-title: Heart Rhythm – volume: 7 start-page: 1042 year: 2014 end-page: 1049 article-title: Left atrium in heart failure with preserved ejection fraction: Structure, function, and significance publication-title: Circ Heart Fail – volume: 24 start-page: 1657 year: 2003 end-page: 1662 article-title: Chronic atrial fibrillation does not influence the magnitude of sympathetic overactivity in patients with heart failure publication-title: Eur Heart J – volume: 8 start-page: 295 year: 2015 end-page: 303 article-title: Left atrial remodeling and function in advanced heart failure with preserved or reduced ejection fraction publication-title: Circ Heart Fail – volume: 33 start-page: 769 year: 2003 end-page: 778 article-title: Mechanisms of renal hyporesponsiveness to ANP in heart failure publication-title: Eur J Clin Invest – volume: 4 start-page: 114 year: 2011 end-page: 120 article-title: Decompensated heart failure is associated with reduced corin levels and decreased cleavage of pro‐atrial natriuretic peptide publication-title: Circ Heart Fail – volume: 110 start-page: 386 year: 2006 end-page: 392 article-title: Chronic heart failure with preserved left ventricular ejection fraction: diagnostic and prognostic value of left atrial size publication-title: Int J Cardiol. – volume: 4 start-page: 255 year: 2002 end-page: 262 article-title: Longstanding atrial fibrillation causes depletion of atrial natriuretic peptide in patients with advanced congestive heart failure publication-title: Eur J Heart Fail – volume: 74 start-page: 2225 year: 1993 end-page: 2233 article-title: Contribution of left ventricular diastolic function to exercise capacity in normal subjects publication-title: J Appl Physiol – volume: 58 start-page: 108 year: 2014 end-page: 116 article-title: Atrial natriuretic peptide: an old hormone or a new cytokine? publication-title: Peptides – volume: 119 start-page: 2516 year: 2009 end-page: 2525 article-title: Atrial fibrillation and heart failure: treatment considerations for a dual epidemic publication-title: Circulation – volume: 10 start-page: 1133 year: 2012 end-page: 1140 article-title: A review of the epidemiological profile of patients with atrial fibrillation and heart failure publication-title: Exp Rev Cardiovasc Ther – volume: 16 start-page: 494 year: 2014 end-page: 508 article-title: Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology publication-title: Eur J Heart Fail – volume: 36 start-page: 733 year: 2015 end-page: 742 article-title: Left atrial function measured by cardiac magnetic resonance imaging in patients with heart failure: clinical associations and prognostic value publication-title: Eur Heart J – volume: 29 start-page: 403 year: 2014 end-page: 407 article-title: Left atrial anatomy and physiology: echo/Doppler assessment publication-title: Curr Opin Cardiol – volume: 22 start-page: 22 year: 2001 end-page: 36 article-title: A clinical appraisal of left atrial function publication-title: Eur Heart J – volume: 47 start-page: 1997 year: 2006 end-page: 2004 article-title: Atrial fibrillation and risk of clinical events in chronic heart failure with and without left ventricular systolic dysfunction: results from the candesartan in heart failure‐assessment of reduction in mortality and morbidity (CHARM) program publication-title: J Am Coll Cardiol – volume: 4 start-page: 388 year: 2011 end-page: 396 article-title: Autonomic remodeling in the left atrium and pulmonary veins in heart failure: creation of a dynamic substrate for atrial fibrillation publication-title: Circ Arrhythm Electrophysiol – volume: 8 start-page: 89 year: 2015 end-page: 97 article-title: Pro‐B‐type natriuretic peptide‐1‐108 processing and degradation in human heart failure publication-title: Circ Heart Fail – volume: 11 start-page: 541 year: 2014 end-page: 551 article-title: Evaluation of the Watchman left atrial appendage closure device publication-title: Exp Rev Med Device – volume: 120 start-page: 1768 year: 2009 end-page: 1774 article-title: ‐terminal pro‐B‐type natriuretic peptide is a major predictor of the development of atrial fibrillation: the Cardiovascular Health Study publication-title: Circulation – volume: 115 start-page: 115 year: 2014 end-page: 130 article-title: Pulmonary arterial hypertension: the clinical syndrome publication-title: Circ Res – volume: 14 start-page: 1608 year: 2012 end-page: 1614 article-title: Small left atrium and mild mitral regurgitation predict super‐response to cardiac resynchronization therapy publication-title: Europace – volume: 82 start-page: 756 year: 1998 end-page: 761 article-title: Increasing degrees of left ventricular filling impairment modulate left atrial function in humans publication-title: Am J Cardiol – volume: 7 start-page: 123 year: 2014 end-page: 130 article-title: Impact of atrial fibrillation on exercise capacity in heart failure with preserved ejection fraction: a RELAX trial ancillary study publication-title: Circ Heart Fail – volume: 35 start-page: 1237 year: 2000 end-page: 1244 article-title: Echocardiographic predictors of clinical outcome in patients with left ventricular dysfunction enrolled in the SOLVD registry and trials: significance of left ventricular hypertrophy. Studies of Left Ventricular Dysfunction publication-title: J Am Coll Cardiol – volume: 70 start-page: 825 year: 1992 end-page: 827 article-title: Relation of exercise capacity in dilated cardiomyopathy to left atrial size and systolic function publication-title: Am J Cardiol – volume: 13 start-page: 91 year: 2008 end-page: 98 article-title: Left atrial remodelling contributes to the progression of asymptomatic left ventricular systolic dysfunction to chronic symptomatic heart failure publication-title: Heart Fail Rev – volume: 16 start-page: 1026 year: 2014 end-page: 1038 article-title: Rationale and design of the soluble guanylate cyclase stimulator in heart failure studies (SOCRATES) publication-title: Eur J Heart Fail – volume: 36 start-page: 1974 year: 2015 end-page: 1982 article-title: The sympathetic/parasympathetic imbalance in heart failure with reduced ejection fraction publication-title: Eur Heart J – volume: 11 start-page: 929 year: 2009 end-page: 936 article-title: Independent relationship of left atrial size and mortality in patients with heart failure: An individual patient meta‐analysis of longitudinal data (MeRGE Heart Failure) publication-title: Eur J Heart Fail – volume: 17 start-page: 580 year: 2015 article-title: Influence of vascular function and pulsatile hemodynamics on cardiac function publication-title: Curr Hypertens Rep – volume: 28 start-page: 2738 year: 2007 end-page: 2748 article-title: Different effects of cardiac resynchronization therapy on left atrial function in patients with either idiopathic or ischaemic dilated cardiomyopathy: a two‐dimensional speckle strain study publication-title: Eur Heart J – volume: 131 start-page: 459 year: 2015 end-page: 468 article-title: Paradoxical muscle sympathetic reflex activation in human heart failure publication-title: Circulation – volume: 25 start-page: 475 year: 2015 end-page: 484 article-title: Atrial remodeling, fibrosis, and atrial fibrillation publication-title: Trends Cardiovasc Med – volume: 33 start-page: 904 year: 2012 end-page: 912 article-title: Echocardiographic diastolic parameters and risk of atrial fibrillation: the Cardiovascular Health Study publication-title: Eur Heart J – volume: 3 start-page: 629 year: 2015 end-page: 636 article-title: Elevated plasma b‐type natriuretic peptide concentrations directly inhibit circulating neprilysin activity in heart failure publication-title: JACC Heart Fail – volume: 166 start-page: 522 year: 2012 end-page: 531 article-title: Endothelial actions of atrial and B‐type natriuretic peptides publication-title: Br J Pharmacol – volume: 13 start-page: 749 year: 1992 end-page: 757 article-title: Abnormal diastolic filling patterns in chronic heart failure – relationship to exercise capacity publication-title: Eur Heart J – volume: 40 start-page: 1425 year: 2002 article-title: Determinants and prognostic value of left atrial volume in patients with dilated cardiomyopathy publication-title: J Am Coll Cardiol – volume: 29 start-page: 2367 year: 2008 end-page: 2372 article-title: Permanent atrial fibrillation affects exercise capacity in chronic heart failure patients publication-title: Eur Heart J – ident: e_1_2_7_28_1 doi: 10.1016/j.cca.2011.10.032 – ident: e_1_2_7_79_1 doi: 10.1161/JAHA.112.005694 – ident: e_1_2_7_82_1 doi: 10.1093/europace/eus075 – ident: e_1_2_7_70_1 doi: 10.1152/ajpheart.00986.2005 – ident: e_1_2_7_85_1 doi: 10.1161/01.HYP.0000254322.96189.85 – ident: e_1_2_7_97_1 doi: 10.1161/CIRCULATIONAHA.112.001039 – ident: e_1_2_7_3_1 doi: 10.1007/s10741-007-9021-6 – ident: e_1_2_7_52_1 doi: 10.1016/j.ijcard.2015.07.028 – ident: e_1_2_7_80_1 doi: 10.1016/j.ijcard.2010.06.016 – ident: e_1_2_7_9_1 doi: 10.1161/CIRCEP.111.962720 – ident: e_1_2_7_43_1 doi: 10.1046/j.1365-2362.2003.01222.x – ident: e_1_2_7_90_1 doi: 10.1016/S0140-6736(12)61227-6 – ident: e_1_2_7_35_1 doi: 10.1126/science.6538050 – ident: e_1_2_7_36_1 doi: 10.1161/HYPERTENSIONAHA.115.06300 – ident: e_1_2_7_37_1 doi: 10.1161/CIRCHEARTFAILURE.109.895581 – ident: e_1_2_7_32_1 doi: 10.1093/eurheartj/ehv132 – ident: e_1_2_7_15_1 doi: 10.1016/j.amjcard.2005.07.126 – ident: e_1_2_7_8_1 doi: 10.1148/rg.351130010 – ident: e_1_2_7_13_1 doi: 10.1007/s11906-015-0580-y – ident: e_1_2_7_63_1 doi: 10.1093/oxfordjournals.eurheartj.a060251 – ident: e_1_2_7_54_1 doi: 10.1016/j.jacc.2007.09.026 – ident: e_1_2_7_50_1 doi: 10.1016/S0195-668X(03)00393-2 – ident: e_1_2_7_93_1 doi: 10.1161/CIRCHEARTFAILURE.113.000748 – ident: e_1_2_7_94_1 doi: 10.1093/eurheartj/ehm443 – ident: e_1_2_7_65_1 doi: 10.1016/0002-9149(92)90572-G – ident: e_1_2_7_14_1 doi: 10.1016/j.echo.2006.08.013 – ident: e_1_2_7_86_1 doi: 10.1016/j.jjcc.2010.08.001 – ident: e_1_2_7_91_1 doi: 10.1056/NEJMoa1409077 – ident: e_1_2_7_12_1 doi: 10.1016/j.jacc.2004.09.054 – ident: e_1_2_7_51_1 doi: 10.1161/CIRCEP.110.959650 – ident: e_1_2_7_62_1 doi: 10.1016/j.ejheart.2004.01.005 – ident: e_1_2_7_41_1 doi: 10.1016/j.eupc.2004.04.006 – ident: e_1_2_7_22_1 doi: 10.1586/erc.12.110 – ident: e_1_2_7_33_1 doi: 10.1161/CIRCRESAHA.116.306082 – ident: e_1_2_7_20_1 doi: 10.1111/echo.13094 – ident: e_1_2_7_61_1 doi: 10.1161/CIRCULATIONAHA.109.873265 – ident: e_1_2_7_56_1 doi: 10.1002/ejhf.62 – ident: e_1_2_7_44_1 doi: 10.1161/01.ATV.zhq0504.7914 – ident: e_1_2_7_73_1 doi: 10.1016/S0735-1097(02)02305-7 – ident: e_1_2_7_27_1 doi: 10.1177/2048872615626355 – ident: e_1_2_7_19_1 doi: 10.1161/CIRCIMAGING.108.813071 – ident: e_1_2_7_69_1 doi: 10.1093/eurheartj/ehn361 – ident: e_1_2_7_71_1 doi: 10.1016/S0735-1097(00)00511-8 – ident: e_1_2_7_24_1 doi: 10.1016/S0140-6736(09)60040-4 – ident: e_1_2_7_100_1 doi: 10.1016/j.jchf.2014.10.011 – ident: e_1_2_7_29_1 doi: 10.1016/j.jchf.2015.03.015 – ident: e_1_2_7_76_1 doi: 10.1016/j.jjcc.2012.01.004 – ident: e_1_2_7_11_1 doi: 10.1097/HCO.0000000000000089 – ident: e_1_2_7_57_1 doi: 10.1016/j.tcm.2014.12.015 – ident: e_1_2_7_87_1 doi: 10.1161/CIRCRESAHA.115.306567 – ident: e_1_2_7_39_1 doi: 10.1136/hrt.2008.164145 – ident: e_1_2_7_95_1 doi: 10.1016/j.jcin.2015.02.014 – ident: e_1_2_7_6_1 doi: 10.1002/ejhf.147 – ident: e_1_2_7_10_1 doi: 10.1111/j.1540-8167.1999.tb00211.x – ident: e_1_2_7_47_1 doi: 10.1093/ckj/sfu050 – ident: e_1_2_7_4_1 doi: 10.1161/CIRCHEARTFAILURE.114.001276 – ident: e_1_2_7_26_1 doi: 10.1016/j.aanat.2006.11.006 – ident: e_1_2_7_60_1 doi: 10.1093/eurheartj/ehr378 – ident: e_1_2_7_31_1 doi: 10.1152/physrev.00017.2002 – ident: e_1_2_7_40_1 doi: 10.1161/HYPERTENSIONAHA.112.193631 – ident: e_1_2_7_53_1 doi: 10.1016/j.pcad.2015.08.004 – ident: e_1_2_7_78_1 doi: 10.1016/j.jacc.2006.01.060 – ident: e_1_2_7_45_1 doi: 10.1016/j.jacc.2007.02.066 – ident: e_1_2_7_64_1 doi: 10.1152/jappl.1993.74.5.2225 – ident: e_1_2_7_83_1 doi: 10.1016/j.repc.2014.05.008 – ident: e_1_2_7_2_1 doi: 10.1053/euhj.1999.2581 – ident: e_1_2_7_30_1 doi: 10.1111/j.1476-5381.2012.01827.x – ident: e_1_2_7_18_1 doi: 10.1016/j.jchf.2015.10.008 – ident: e_1_2_7_16_1 doi: 10.1093/ehjci/jeu165 – ident: e_1_2_7_77_1 doi: 10.1093/eurheartj/ehu405 – volume: 36 start-page: 257 year: 2015 ident: e_1_2_7_96_1 article-title: Recurrent atrial fibrillation reduced after renal denervation with pulmonary vein ablation in select patients publication-title: Eur Heart J – ident: e_1_2_7_23_1 doi: 10.1161/CIRCULATIONAHA.108.821306 – ident: e_1_2_7_34_1 doi: 10.1016/j.peptides.2014.06.011 – volume: 129 start-page: 1 year: 2014 ident: e_1_2_7_5_1 article-title: The left atrium: From the research laboratory to the clinic publication-title: Cardiology doi: 10.1159/000360935 – ident: e_1_2_7_99_1 doi: 10.1586/17434440.2014.940315 – ident: e_1_2_7_17_1 doi: 10.1161/CIRCHEARTFAILURE.114.001667 – ident: e_1_2_7_84_1 doi: 10.1016/j.amjcard.2005.09.143 – ident: e_1_2_7_21_1 doi: 10.1161/CIRCRESAHA.115.301146 – ident: e_1_2_7_58_1 doi: 10.1089/ars.2013.5542 – ident: e_1_2_7_67_1 doi: 10.1136/heartjnl-2012-302007 – ident: e_1_2_7_75_1 doi: 10.1016/j.ijcard.2005.08.049 – ident: e_1_2_7_68_1 doi: 10.1161/CIRCHEARTFAILURE.113.000568 – ident: e_1_2_7_59_1 doi: 10.1016/S0002-9149(98)00452-4 – ident: e_1_2_7_88_1 doi: 10.1016/j.cardfail.2015.07.008 – ident: e_1_2_7_25_1 doi: 10.1016/j.jjcc.2011.01.002 – ident: e_1_2_7_42_1 doi: 10.1016/S1388-9842(01)00232-X – ident: e_1_2_7_92_1 doi: 10.1016/j.hrthm.2014.01.033 – ident: e_1_2_7_38_1 doi: 10.1161/CIRCHEARTFAILURE.114.001174 – ident: e_1_2_7_72_1 doi: 10.1093/eurjhf/hfp112 – ident: e_1_2_7_74_1 doi: 10.1016/j.amjcard.2008.02.099 – ident: e_1_2_7_55_1 doi: 10.1016/j.jacc.2015.06.1313 – ident: e_1_2_7_46_1 doi: 10.1016/j.amjcard.2013.03.055 – volume: 35 start-page: 136 year: 2008 ident: e_1_2_7_66_1 article-title: Left atrial size may predict exercise capacity and cardiovascular events in patients with heart failure publication-title: Tex Heart Inst J – ident: e_1_2_7_89_1 doi: 10.1016/j.jchf.2015.03.011 – ident: e_1_2_7_81_1 doi: 10.1016/j.ijcard.2013.05.028 – ident: e_1_2_7_98_1 doi: 10.1016/j.ijcard.2015.03.198 – ident: e_1_2_7_49_1 doi: 10.1161/CIRCULATIONAHA.114.010765 – ident: e_1_2_7_7_1 doi: 10.1002/ejhf.135 – ident: e_1_2_7_48_1 doi: 10.1093/eurheartj/ehv087 |
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| SubjectTerms | Atrial Fibrillation - etiology Atrial Fibrillation - physiopathology Atrial Function, Left Atrial Natriuretic Factor - metabolism Dilatation Heart Atria - metabolism Heart Atria - physiopathology Heart failure Heart Failure - metabolism Heart Failure - physiopathology Humans Left atrium Natriuretic peptide Sympathetic Nervous System - physiopathology Vasoconstriction Vasopressins - metabolism Ventricular Dysfunction, Left - complications Ventricular Dysfunction, Left - physiopathology |
| Title | Global left atrial failure in heart failure |
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