ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections

Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent the official practice recommendations of the American...

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Bibliographic Details
Published in:The American journal of gastroenterology Vol. 116; no. 6; pp. 1124 - 1147
Main Authors: Kelly, Colleen R., Fischer, Monika, Allegretti, Jessica R., LaPlante, Kerry, Stewart, David B., Limketkai, Berkeley N., Stollman, Neil H.
Format: Journal Article
Language:English
Published: United States Wolters Kluwer 01.06.2021
Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
Subjects:
Anti-Bacterial Agents - therapeutic use
Antibiotics
Clostridioides difficile - isolation & purification
Clostridium Infections - diagnosis
Clostridium Infections - drug therapy
Clostridium Infections - prevention & control
Diarrhea - drug therapy
Diarrhea - microbiology
Diarrhea - prevention & control
Disease prevention
Gastroenterology
Humans
Infections
Infectious diseases
Inflammation - drug therapy
Inflammation - microbiology
Inflammation - prevention & control
Inflammatory bowel disease
Long term health care
Probiotics
Recurrence
Risk factors
United States > US
ISSN:0002-9270, 1572-0241, 1572-0241
Online Access:Get full text
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Summary:Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation process. In instances where the evidence was not appropriate for Grading of Recommendations Assessment, Development, and Evaluation but there was consensus of significant clinical merit, key concept statements were developed using expert consensus. These guidelines are meant to be broadly applicable and should be viewed as the preferred, but not the only, approach to clinical scenarios.
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ISSN:0002-9270
1572-0241
1572-0241
DOI:10.14309/ajg.0000000000001278