A secondary analysis of cortical atrophy and plasma amyloid β patterns in older patients with cognitive frailty undergoing elective surgery

Background The etiology of cognitive impairment in frailty may be related to age or to an independent neurodegenerative process, such as Alzheimer’s disease (AD). In this secondary analysis, we examine cognitive frailty in patients aged 65 and older undergoing elective surgery, and explore associati...

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Bibliographic Details
Published in:	BMC geriatrics Vol. 25; no. 1; pp. 484 - 16
Main Authors:	Mörgeli, Rudolf, Borchers, Friedrich, Feinkohl, Insa, Piper, Sophie K., Pischon, Tobias, Slooter, Arjen J.C., Spies, Claudia, Wiebach, Janine, Winterer, Georg, Zacharias, Norman, Lammers-Lietz, Florian
Format:	Journal Article
Language:	English
Published:	London BioMed Central 02.07.2025 Springer Nature B.V BMC
Subjects:	Aged Aged, 80 and over Aging Alzheimer Disease - blood Alzheimer's disease Amyloid Amyloid beta-Peptides - blood Amyloidβ Atrophy Atrophy - blood Biomarkers Cerebral Cortex - diagnostic imaging Cerebral Cortex - pathology Cognition Cognition & reasoning Cognitive ability Cognitive Dysfunction - blood Cognitive frailty Cognitive impairment Comorbidity Cortical atrophy Delirium Dementia Elective surgery Elective Surgical Procedures - trends Etiology Executive function Female Frail Frail Elderly - psychology Frailty Frailty - blood Frailty - psychology Geriatrics Geriatrics/Gerontology Gerontology Health risk assessment Humans Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medicine Medicine & Public Health Mini-Mental State Examination MRI Neurodegenerative diseases Neuropathology Neuropsychological Tests Neuropsychology Older people Pathology Patients Phenotypes Registration Rehabilitation Surgery White people β-Amyloid Berlin Germany Netherlands Germany Aging Frailty Cognitive frailty Amyloidβ MRI Cortical atrophy
ISSN:	1471-2318, 1471-2318
Online Access:	Get full text
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