SLAMseq reveals potential transfer of RNA from liver to kidney in the mouse

Extracellular RNA (exRNA) mediates intercellular communication in lower animals; whether it serves a signalling function in mammals is uncertain. Reductionist experiments, in which a single RNA is over-expressed or tagged, have shown RNA transfer between tissues but may not be relevant to normal phy...

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Bibliographic Details
Published in:	Nature communications Vol. 16; no. 1; pp. 7413 - 14
Main Authors:	Hunter, Robert W., Sun, Jialin, Palmer, Trecia, Czopek, Alicja, Nespoux, Josselin, Bailey, Matthew A., Dhaun, Neeraj, Buck, Amy H., Dear, James W.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 11.08.2025 Nature Publishing Group Nature Portfolio
Subjects:	45/71 45/91 631/337 692/4022 Alkylation Analgesics Animals Cell interactions Conversion Experiments Gene sequencing Genes Hepatocytes Hepatocytes - metabolism Humanities and Social Sciences Hypotheses Incorporation Injury prevention Kidney - metabolism Kidneys Kruskal-Wallis test Labeling Labels Liver Liver - metabolism Male Metabolism Mice Mice, Inbred C57BL MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA multidisciplinary Physiology Ribonucleic acid RNA RNA - metabolism RNA Transport RNA, Messenger - genetics RNA, Messenger - metabolism Science Science (multidisciplinary) Sequence Analysis, RNA - methods Spleen Thiouracil - chemistry Thiouracil - metabolism
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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