Dopaminergic Projections From the Ventral Tegmental Area to the Nucleus Accumbens Modulate Sevoflurane Anesthesia in Mice

The role of the dopaminergic pathway in general anesthesia and its potential mechanisms are still unknown. In this study, we usedc-Fos staining combined with calcium fiber photometry recording to explore the activity of ventral tegmental area (VTA) dopaminergic neurons(VTA-DA) and nucleus accumbens...

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Bibliographic Details
Published in:	Frontiers in cellular neuroscience Vol. 15; p. 671473
Main Authors:	Gui, Huan, Liu, Chengxi, He, Haifeng, Zhang, Jie, Chen, Hong, Zhang, Yi
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Research Foundation 30.04.2021 Frontiers Media S.A
Subjects:	Anesthesia c-Fos protein Calcium calcium fiber photometry recording Cellular Neuroscience Dopamine Dopamine receptors dopamine sensors dopaminergic (DA) neuron EEG Electroencephalography General anesthesia Genetics Information processing Laboratory animals Life sciences Neurons Nucleus accumbens Optics Photometry Righting reflex Sevoflurane Sleep Variance analysis ventral tegmental area Ventral tegmentum Viruses United States > US China dopamine sensors dopaminergic (DA) neuron sevoflurane calcium fiber photometry recording ventral tegmental area
ISSN:	1662-5102, 1662-5102
Online Access:	Get full text
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