Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis

IFN-γ-producing Th1 and IL-17-producing Th17 cells are the key participants in various autoimmune diseases, including multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). Although both of these T cell subsets are known to be regulated by specific transcription fa...

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Vydané v:	The Journal of immunology (1950) Ročník 187; číslo 5; s. 2213
Hlavní autori:	Murugaiyan, Gopal, Beynon, Vanessa, Mittal, Akanksha, Joller, Nicole, Weiner, Howard L
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 01.09.2011
Predmet:	Animals CD4-Positive T-Lymphocytes - immunology Encephalomyelitis, Autoimmune, Experimental - genetics Encephalomyelitis, Autoimmune, Experimental - immunology Gene Silencing Inflammation - genetics Inflammation - immunology Mice Mice, Inbred C57BL Mice, Knockout MicroRNAs - genetics MicroRNAs - immunology Reverse Transcriptase Polymerase Chain Reaction T-Lymphocyte Subsets - immunology
ISSN:	1550-6606, 1550-6606
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