Effects of CETP inhibition on triglyceride-rich lipoprotein composition and apoB-48 metabolism

Cholesteryl ester transfer protein (CETP) facilitates the transfer of HDL cholesteryl ester to triglyceride-rich lipoproteins (TRL). This study aimed to determine the effects of CETP inhibition with torcetrapib on TRL composition and apoB-48 metabolism. Study subjects with low HDL cholesterol (<4...

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Bibliographic Details
Published in:	Journal of lipid research Vol. 53; no. 6; pp. 1190 - 1199
Main Authors:	Diffenderfer, Margaret R, Brousseau, Margaret E, Millar, John S, Barrett, P Hugh R, Nartsupha, Chorthip, Schaefer, Peter M, Wolfe, Megan L, Dolnikowski, Gregory G, Rader, Daniel J, Schaefer, Ernst J
Format:	Journal Article
Language:	English
Published:	United States Elsevier 01.06.2012
Subjects:	apolipoprotein Apolipoprotein B-48 - blood Apolipoprotein B-48 - metabolism Cholesterol Ester Transfer Proteins - antagonists & inhibitors cholesteryl ester transfer protein Female Humans Kinetics lipoprotein kinetics Lipoproteins - blood Lipoproteins - chemistry Lipoproteins - metabolism Male Middle Aged postprandial metabolism Quinolines - pharmacology torcetrapib Triglycerides
ISSN:	1539-7262, 0022-2275, 1539-7262
Online Access:	Get full text
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