Enhancement of stability and skin permeation by sucrose stearate and cyclodextrins in progesterone nanoemulsions

Lecithin-based nanoemulsions are colloidal drug delivery systems which offer fundamental advantages in topical therapy, such as excellent skin permeation of lipophilic drugs; however, their physicochemical long-term stability is usually rather poor without the use of additional synthetic surfactants...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	International journal of pharmaceutics Ročník 393; číslo 1; s. 153 - 161
Hlavní autori:	Klang, Victoria, Matsko, Nadejda, Zimmermann, Anna-Maria, Vojnikovic, Emina, Valenta, Claudia
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Amsterdam Elsevier B.V 30.06.2010 Elsevier
Predmet:	alpha-Cyclodextrins - pharmacology Animals beta-Cyclodextrins - pharmacology Biological and medical sciences Calorimetry, Differential Scanning Chemistry, Pharmaceutical Cryoelectron Microscopy Cyclodextrin Cyclodextrins - chemistry Cyclodextrins - pharmacology Drug Compounding Drug Stability Emulsions Excipients - chemistry Excipients - pharmacology gamma-Cyclodextrins - pharmacology General pharmacology Medical sciences Microscopy, Electron, Transmission Nanoemulsion Nanoparticles Permeability Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Progesterone Progesterone - chemistry Progesterone - metabolism Skin - drug effects Skin - metabolism Skin Absorption - drug effects Sphingosine - analogs & derivatives Sphingosine - chemistry Submicron emulsion Sucrose - analogs & derivatives Sucrose - chemistry Sucrose - pharmacology Sucrose stearate Surface Properties Swine Technology, Pharmaceutical - methods Time Factors Submicron emulsion Cyclodextrin Progesterone Nanoemulsion Sucrose stearate Stability Pharmaceutical technology Sucrose Permeation Stearate Progestagen Emulsion Oside polymer Skin Inclusion compound Sex steroid hormone Physicochemical properties
ISSN:	0378-5173, 1873-3476, 1873-3476
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!