The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

The complexity of chromatin architecture presents a significant barrier to the ability of the DNA repair machinery to access and repair DNA double-strand breaks (DSBs). Consequently, remodeling of the chromatin landscape adjacent to DSBs is vital for efficient DNA repair. Here, we demonstrate that D...

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Veröffentlicht in:	The Journal of cell biology Jg. 191; H. 1; S. 31
Hauptverfasser:	Xu, Ye, Sun, Yingli, Jiang, Xiaofeng, Ayrapetov, Marina K, Moskwa, Patryk, Yang, Shenghong, Weinstock, David M, Price, Brendan D
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 04.10.2010
Schlagworte:	Chromatin - metabolism Chromatin Assembly and Disassembly DNA Damage DNA Helicases - metabolism DNA Helicases - physiology DNA Repair DNA-Binding Proteins - metabolism DNA-Binding Proteins - physiology Histone Acetyltransferases - metabolism Histone Acetyltransferases - physiology Histones - metabolism Humans Lysine Acetyltransferase 5 Nucleosomes - metabolism Protein Stability Ubiquitination
ISSN:	1540-8140, 1540-8140
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