Highly reactive anti-myelin oligodendrocyte glycoprotein antibodies differentiate demyelinating diseases from viral encephalitis in children

Background: Myelin oligodendrocyte glycoprotein (MOG) may be implicated in the immunopathogenesis of multiple sclerosis (MS) inducing demyelination in the animal model of MS. In adults reported anti-MOG antibody frequencies have been variable across a number of studies and can also be detected in co...

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Bibliographic Details
Published in:	Multiple sclerosis Vol. 17; no. 3; pp. 297 - 302
Main Authors:	Lalive, PH, Häusler, MG, Maurey, H, Mikaeloff, Y, Tardieu, M, Wiendl, H, Schroeter, M, Hartung, HP, Kieseier, BC, Menge, T
Format:	Journal Article
Language:	English
Published:	London, England SAGE Publications 01.03.2011 Sage Publications Sage Publications Ltd
Subjects:	Adolescent Autoantibodies - blood Biological and medical sciences Biomarkers - blood Chi-Square Distribution Child Child, Preschool Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Demyelinating Diseases - diagnosis Demyelinating Diseases - immunology Diagnosis, Differential Encephalitis, Viral - diagnosis Encephalitis, Viral - immunology Encephalomyelitis, Acute Disseminated - diagnosis Encephalomyelitis, Acute Disseminated - immunology Enzyme-Linked Immunosorbent Assay Epstein-Barr virus Epstein-Barr Virus Infections - diagnosis Epstein-Barr Virus Infections - immunology Female Flow Cytometry France Germany Humans Immunity, Humoral Male Medical sciences Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Myelin Basic Protein Myelin Proteins Myelin-Associated Glycoprotein - immunology Myelin-Oligodendrocyte Glycoprotein Nerve Tissue Proteins - immunology Neurology Predictive Value of Tests Retrospective Studies Transcription Factors - immunology France Germany acute disseminated encephalomyelitis paediatric multiple sclerosis myelin/oligodendrocyte glycoprotein autoantibodies Epstein–Barr virus antibody assays Autoimmunity Multiple sclerosis Encephalomyelitis Neuroglia Epstein Barr virus Epstein―Barr virus Inflammatory disease Oligodendrocyte Degenerative disease Child Gammaherpesvirinae Human Encephalitis Nervous system diseases Myelin Herpesviridae Glycoprotein Autoantibody Cerebral disorder Infection Virus Viral disease Central nervous system disease Spinal cord disease
ISSN:	1352-4585, 1477-0970, 1477-0970
Online Access:	Get full text
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