Serum thyroid-stimulating hormone concentration and morbidity from cardiovascular disease and fractures in patients on long-term thyroxine therapy

For patients on T(4) replacement, the dose is guided by serum TSH concentrations, but some patients request higher doses due to adverse symptoms. The aim of the study was to determine the safety of patients having a low but not suppressed serum TSH when receiving long-term T(4) replacement. We condu...

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Bibliographic Details
Published in:	The journal of clinical endocrinology and metabolism Vol. 95; no. 1; p. 186
Main Authors:	Flynn, Robert W, Bonellie, Sandra R, Jung, Roland T, MacDonald, Thomas M, Morris, Andrew D, Leese, Graham P
Format:	Journal Article
Language:	English
Published:	United States 01.01.2010
Subjects:	Adolescent Adult Aged Aged, 80 and over Cardiovascular Diseases - blood Cardiovascular Diseases - epidemiology Comorbidity Female Fractures, Bone - blood Fractures, Bone - epidemiology Fractures, Bone - etiology Hormone Replacement Therapy - adverse effects Humans Hypothyroidism - blood Hypothyroidism - drug therapy Hypothyroidism - epidemiology Male Middle Aged Osmolar Concentration Osteoporosis - blood Osteoporosis - complications Osteoporosis - epidemiology Thyrotropin - blood Thyroxine - adverse effects Thyroxine - therapeutic use Time Factors Young Adult
ISSN:	1945-7197, 1945-7197
Online Access:	Get more information
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