Medical Treatment for Endometriosis: Tolerability, Quality of Life and Adherence

Endometriosis is associated with painful symptoms, infertility, sexological difficulties, and psychological suffering. All these symptoms have a negative impact on the overall quality of life of women with the disease, with significant personal, social and economic costs. Several medical options are...

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Bibliographic Details
Published in:Frontiers in Global Women's Health Vol. 2; p. 729601
Main Authors: Barbara, Giussy, Buggio, Laura, Facchin, Federica, Vercellini, Paolo
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media SA 27.09.2021
Frontiers Media S.A
Subjects:
Agonists
Amenorrhea
Birth control
Chronic illnesses
Costs
Drug dosages
Endometriosis
Endometrium
estrogen-progestins
Estrogens
Global Women's Health
GnRH agonists
GnRH antagonists
Infertility
Medical treatment
Menstruation
Pain
Patient compliance
Pregnancy
Quality of life
Sexual disorders
Womens health
GnRH agonists
medical treatment
tolerability
endometriosis
GnRH antagonists
estrogen-progestins
quality of life
ISSN:2673-5059, 2673-5059
Online Access:Get full text
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Summary:Endometriosis is associated with painful symptoms, infertility, sexological difficulties, and psychological suffering. All these symptoms have a negative impact on the overall quality of life of women with the disease, with significant personal, social and economic costs. Several medical options are available to manage symptomatic endometriosis. The pharmacological treatment for endometriosis-related pain may be necessary for decades, or at least until there is a desire for pregnancy or physiologic menopause occurs. In this perspective, clinicians should consider not only the efficacy, but also side effects, tolerability, and costs, along with women's preferences toward different treatments. In this mini-review, we analyzed the pros and cons of the available drugs for the medical therapy of endometriosis, such as estrogen-progestins, progestins, GnRH agonist and GnRH antagonists.
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This article was submitted to Quality of Life, a section of the journal Frontiers in Global Women's Health
Reviewed by: Jeung-Im Kim, School of Nursing, South Korea; Péter Dr. Török, University of Debrecen, Hungary; Matteo Morotti, Centre Hospitalier Universitaire Vaudois (CHUV), Switzerland
Edited by: Georgina Louise Jones, Leeds Beckett University, United Kingdom
ISSN:2673-5059
2673-5059
DOI:10.3389/fgwh.2021.729601