The anticancer effects of HDAC inhibitors require the immune system

Histone deacetylase inhibitors (HDACis) are known to exert immunomodulatory effects. We have recently demonstrated that the therapeutic efficacy of HDACis against aggressive B-cell lymphoma and colon carcinoma relies on a functional immune system, in particular on the production of interferon γ (IFN...

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Vydané v:	Oncoimmunology Ročník 3; číslo 1; s. e27414
Hlavní autori:	West, Alison C, Smyth, Mark J, Johnstone, Ricky W
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Taylor & Francis 01.01.2014 Landes Bioscience
Predmet:	anticancer immunity anticancer therapy Author's View epigenetic regulatory agent HDACi immunogenic cell death immunotherapy anticancer immunity anticancer therapy epigenetic regulatory agent HDACi immunogenic cell death immunotherapy
ISSN:	2162-402X, 2162-4011, 2162-402X
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