The anticancer effects of HDAC inhibitors require the immune system

Histone deacetylase inhibitors (HDACis) are known to exert immunomodulatory effects. We have recently demonstrated that the therapeutic efficacy of HDACis against aggressive B-cell lymphoma and colon carcinoma relies on a functional immune system, in particular on the production of interferon γ (IFN...

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Bibliographic Details

Published in:	Oncoimmunology Vol. 3; no. 1; p. e27414
Main Authors:	West, Alison C, Smyth, Mark J, Johnstone, Ricky W
Format:	Journal Article
Language:	English
Published:	United States Taylor & Francis 01.01.2014 Landes Bioscience
Subjects:	anticancer immunity anticancer therapy Author's View epigenetic regulatory agent HDACi immunogenic cell death immunotherapy anticancer immunity anticancer therapy epigenetic regulatory agent HDACi immunogenic cell death immunotherapy
ISSN:	2162-402X, 2162-4011, 2162-402X
Online Access:	Get full text
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