Rapidly growing non-tuberculous mycobacteria infection of prosthetic knee joints: A report of two cases

Non-tuberculous mycobacteria (NTM) cause prosthetic knee joint infections in rare cases. Infections with rapidly growing non-tuberculous mycobacteria (RGNTM) are difficult to treat due to their aggressive clinical behavior and resistance to antibiotics. Infections of a prosthetic knee joint by RGNTM...

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Vydané v:The knee Ročník 24; číslo 4; s. 869 - 875
Hlavní autori: Kim, Manyoung, Ha, Chul-Won, Jang, Jae Won, Park, Yong-Beom
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Netherlands Elsevier B.V 01.08.2017
Elsevier Limited
Predmet:
Aged
Aged, 80 and over
Aggressive behavior
Anti-Bacterial Agents - therapeutic use
Antibiotics
Arthrodesis
Arthroplasty
Arthroplasty, Replacement, Knee - adverse effects
Biopsy
Blood
Cement
Female
Humans
Joint diseases
Joint surgery
Knee
Knee Joint - microbiology
Knee Joint - surgery
Knee Prosthesis - adverse effects
Knee Prosthesis - microbiology
Laboratories
Mycobacterium abscessus
Mycobacterium Infections, Nontuberculous - diagnosis
Mycobacterium Infections, Nontuberculous - drug therapy
Neutrophils
Non-tuberculous mycobacteria
Nontuberculous Mycobacteria - isolation & purification
Nosocomial infections
Orthopedics
Polyethylene
Prostheses
Prosthesis-Related Infections - diagnosis
Prosthesis-Related Infections - drug therapy
Prosthesis-Related Infections - microbiology
Prosthetic joint infection
Prosthetics
Rapidly growing mycobacteria
Staphylococcus infections
Surgery
Transplants & implants
Tuberculosis
Non-tuberculous mycobacteria
Rapidly growing mycobacteria
Prosthetic joint infection
Mycobacterium abscessus
ISSN:0968-0160, 1873-5800, 1873-5800
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Popis
Shrnutí:Non-tuberculous mycobacteria (NTM) cause prosthetic knee joint infections in rare cases. Infections with rapidly growing non-tuberculous mycobacteria (RGNTM) are difficult to treat due to their aggressive clinical behavior and resistance to antibiotics. Infections of a prosthetic knee joint by RGNTM have rarely been reported. A standard of treatment has not yet been established because of the rarity of the condition. In previous reports, diagnoses of RGNTM infections in prosthetic knee joints took a long time to reach because the condition was not suspected, due to its rarity. In addition, it is difficult to identify RGNTM in the lab because special identification tests are needed. In previous reports, after treatment for RGNTM prosthetic infections, knee prostheses could not be re-implanted in all cases but one, resulting in arthrodesis or resection arthroplasty; this was most likely due to the aggressiveness of these organisms. In the present report, two cases of prosthetic knee joint infection caused by RGNTM (Mycobacterium abscessus) are described that were successfully treated, and in which prosthetic joints were finally reimplanted in two-stage revision surgery.
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ISSN:0968-0160
1873-5800
1873-5800
DOI:10.1016/j.knee.2017.04.015