Investigations on Zinc Isotope Fractionation in Breast Cancer Tissue Using in vitro Cell Culture Uptake-Efflux Experiments

Zinc (Zn) accumulates in breast cancer tumors compared to adjacent healthy tissue. Clinical samples of breast cancer tissue show light Zn isotopic compositions (δ 66 Zn) relative to healthy tissue. The underlying mechanisms causing such effects are unknown. To investigate if the isotopic discriminat...

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Bibliographic Details
Published in:	Frontiers in medicine Vol. 8; p. 746532
Main Authors:	Schilling, Kathrin, Harris, Adrian L., Halliday, Alex N., Schofield, Christopher J., Sheldon, Helen, Haider, Syed, Larner, Fiona
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media SA 20.01.2022 Frontiers Media S.A
Subjects:	Acids Biofilms Biomarkers Breast cancer Cell growth Copper Effluents efflux Experiments Isotopes Ligands Light MDA-MB-231 Medicine Penicillin Proteins Tissues uptake ZIP Zn isotopes United Kingdom > UK United States > US ZIP breast cancer efflux uptake Zn isotopes MDA-MB-231
ISSN:	2296-858X, 2296-858X
Online Access:	Get full text
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