Aging alters gene expression of growth and remodeling factors in human skeletal muscle both at rest and in response to acute resistance exercise

The purpose of this investigation was to compare expression of genes that function in inflammation and stress, cell structure and signaling, or remodeling and growth in skeletal muscle of young (32 +/- 7 yr, n = 15) and elderly (72 +/- 5 yr, n = 16) healthy subjects before and after a bout of resist...

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Bibliographic Details
Published in:	Physiological genomics Vol. 32; no. 3; p. 393
Main Authors:	Dennis, Richard A, Przybyla, Beata, Gurley, Cathy, Kortebein, Patrick M, Simpson, Pippa, Sullivan, Dennis H, Peterson, Charlotte A
Format:	Journal Article
Language:	English
Published:	United States 19.02.2008
Subjects:	Actins - biosynthesis Actins - genetics Adult Aged Aging - genetics Aging - metabolism Ciliary Neurotrophic Factor - biosynthesis Ciliary Neurotrophic Factor - genetics Gene Expression Profiling Gene Expression Regulation - physiology Humans Insulin-Like Growth Factor Binding Protein 5 - biosynthesis Insulin-Like Growth Factor Binding Protein 5 - genetics Insulin-Like Growth Factor I - biosynthesis Insulin-Like Growth Factor I - genetics Intercellular Signaling Peptides and Proteins - biosynthesis Intercellular Signaling Peptides and Proteins - genetics Male Matrix Metalloproteinase 2 - biosynthesis Matrix Metalloproteinase 2 - genetics Muscle Proteins - biosynthesis Muscle Proteins - genetics Muscle, Skeletal - growth & development Muscle, Skeletal - metabolism Myostatin Rest - physiology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis RNA, Messenger - genetics Tissue Inhibitor of Metalloproteinase-1 - biosynthesis Tissue Inhibitor of Metalloproteinase-1 - genetics Transforming Growth Factor beta - biosynthesis Transforming Growth Factor beta - genetics Weight Lifting - physiology
ISSN:	1531-2267, 1531-2267
Online Access:	Get more information
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