APF and dentifrice effect on root dentin demineralization and biofilm

Because dentin is more caries-susceptible than enamel, its demineralization may be more influenced by additional fluoride (F). We hypothesized that a combination of professional F, applied as acidulated phosphate F (APF), and use of 1100-ppm-F dentifrice would provide additional protection for denti...

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Podrobná bibliografie
Vydáno v:	Journal of dental research Ročník 90; číslo 1; s. 77
Hlavní autoři:	Vale, G C, Tabchoury, C P M, Del Bel Cury, A A, Tenuta, L M A, ten Cate, J M, Cury, J A
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.01.2011
Témata:	Acidulated Phosphate Fluoride - administration & dosage Acidulated Phosphate Fluoride - therapeutic use Adult Apatites - analysis Biofilms - drug effects Calcium Fluoride - analysis Cariogenic Agents - adverse effects Cariostatic Agents - administration & dosage Cariostatic Agents - therapeutic use Cross-Over Studies Dental Plaque - microbiology Dentifrices - administration & dosage Dentifrices - therapeutic use Dentin - drug effects Dentin - microbiology Double-Blind Method Drug Combinations Fluorides - administration & dosage Fluorides - therapeutic use Gels Hardness Humans Microradiography Placebos Sucrose - adverse effects Time Factors Tooth Demineralization - prevention & control Tooth Root - drug effects Tooth Root - microbiology Young Adult
ISSN:	1544-0591, 1544-0591
On-line přístup:	Zjistit podrobnosti o přístupu
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Popis
Shrnutí:	Because dentin is more caries-susceptible than enamel, its demineralization may be more influenced by additional fluoride (F). We hypothesized that a combination of professional F, applied as acidulated phosphate F (APF), and use of 1100-ppm-F dentifrice would provide additional protection for dentin compared with 1100-ppm-F alone. Twelve adult volunteers wore palatal appliances containing root dentin slabs, which were subjected, during 4 experimental phases of 7 days each, to biofilm accumulation and sucrose exposure 8x/day. The volunteers were randomly assigned to the following treatments: placebo dentifrice (PD), 1100-ppm-F dentifrice (FD), APF + PD, and APF+FD. APF gel (1.23% F) was applied to the slabs once at the beginning of the experimental phase, and the dentifrices were used 3x/day. APF and FD increased F concentration in biofilm fluid and reduced root dentin demineralization, presenting an additive effect. Analysis of the data suggests that the combination of APF gel application and daily regular use of 1100-ppm-F dentifrice may provide additional protection against root caries compared with the dentifrice alone.
Bibliografie:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Undefined-3
ISSN:	1544-0591 1544-0591
DOI:	10.1177/0022034510383428