Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor

The removal of unwanted or damaged mitochondria by autophagy, a process called mitophagy, is essential for key events in development, cellular homeostasis, tumor suppression, and prevention of neurodegeneration and aging. However, the precise mechanisms of mitophagy remain uncertain. Here, we identi...

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Veröffentlicht in:	Cell Jg. 168; H. 1-2; S. 224 - 238.e10
Hauptverfasser:	Wei, Yongjie, Chiang, Wei-Chung, Sumpter, Jr, Rhea, Mishra, Prashant, Levine, Beth
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 12.01.2017
Schlagworte:	Aging - metabolism Animals Autophagosomes - metabolism Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - metabolism Embryo, Nonmammalian - metabolism Membrane Proteins - metabolism Mitochondrial Membranes - metabolism Repressor Proteins - metabolism mitophagy prohibitin 2 autophagy
ISSN:	1097-4172
Online-Zugang:	Weitere Angaben
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