Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor

The removal of unwanted or damaged mitochondria by autophagy, a process called mitophagy, is essential for key events in development, cellular homeostasis, tumor suppression, and prevention of neurodegeneration and aging. However, the precise mechanisms of mitophagy remain uncertain. Here, we identi...

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Bibliographic Details

Published in:	Cell Vol. 168; no. 1-2; pp. 224 - 238.e10
Main Authors:	Wei, Yongjie, Chiang, Wei-Chung, Sumpter, Jr, Rhea, Mishra, Prashant, Levine, Beth
Format:	Journal Article
Language:	English
Published:	United States 12.01.2017
Subjects:	Aging - metabolism Animals Autophagosomes - metabolism Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - metabolism Embryo, Nonmammalian - metabolism Membrane Proteins - metabolism Mitochondrial Membranes - metabolism Repressor Proteins - metabolism mitophagy prohibitin 2 autophagy
ISSN:	1097-4172
Online Access:	Get more information
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