Molecular topography of an entire nervous system

We have produced gene expression profiles of all 302 neurons of the C. elegans nervous system that match the single-cell resolution of its anatomy and wiring diagram. Our results suggest that individual neuron classes can be solely identified by combinatorial expression of specific gene families. Fo...

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Bibliographic Details
Published in:	Cell Vol. 184; no. 16; p. 4329
Main Authors:	Taylor, Seth R, Santpere, Gabriel, Weinreb, Alexis, Barrett, Alec, Reilly, Molly B, Xu, Chuan, Varol, Erdem, Oikonomou, Panos, Glenwinkel, Lori, McWhirter, Rebecca, Poff, Abigail, Basavaraju, Manasa, Rafi, Ibnul, Yemini, Eviatar, Cook, Steven J, Abrams, Alexander, Vidal, Berta, Cros, Cyril, Tavazoie, Saeed, Sestan, Nenad, Hammarlund, Marc, Hobert, Oliver, Miller, 3rd, David M
Format:	Journal Article
Language:	English
Published:	United States 05.08.2021
Subjects:	Animals Caenorhabditis elegans - genetics Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Fluorescent Dyes - metabolism Gene Expression Regulation, Developmental Genes, Reporter Larva - metabolism Nervous System - metabolism Neurons - metabolism Neuropeptides - genetics Neuropeptides - metabolism Nucleotide Motifs - genetics Regulatory Sequences, Nucleic Acid - genetics RNA-Seq Signal Transduction - genetics Transcription Factors - metabolism Transcription, Genetic C. elegans cell adhesion molecules RNA-seq neuron single-cell connectome neuropeptides gene regulatory motifs
ISSN:	1097-4172, 1097-4172
Online Access:	Get more information
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