mRNA-Based Genetic Reprogramming

The discovery that ordinary skin cells can be turned into pluripotent stem cells by the forced expression of defined factors has raised hopes that personalized regenerative treatments based on immunologically compatible material derived from a patient's own cells might be realized in the not-to...

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Veröffentlicht in:	Molecular therapy Jg. 27; H. 4; S. 729
Hauptverfasser:	Warren, Luigi, Lin, Cory
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 10.04.2019
Schlagworte:	Cell Differentiation - genetics Cellular Reprogramming - genetics Fibroblasts - metabolism Genetic Vectors Humans Induced Pluripotent Stem Cells - metabolism Induced Pluripotent Stem Cells - transplantation Nucleosides - genetics RNA, Messenger - genetics RNA, Small Interfering - genetics Transfection iPSCs messenger RNA reprogramming modified RNA mRNA reprogramming synthetic mRNA cellular reprogramming induced pluripotent stem cells
ISSN:	1525-0024, 1525-0024
Online-Zugang:	Weitere Angaben
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