Early evolution of nutritional status and body composition after kidney transplantation

Previous series have dealt with nutritional status after kidney transplantation. However, few studies have described the outcome of body composition after kidney transplantation. A total of 44 cadaver kidney transplant recipients (28 men and 16 women) were followed prospectively during the first pos...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:American journal of kidney diseases Ročník 40; číslo 3; s. 629
Hlavní autoři: El Haggan, Wael, Vendrely, Benoît, Chauveau, Philippe, Barthe, Nicole, Castaing, Françoise, Berger, Franck, de Précigout, Valérie, Potaux, Luc, Aparicio, Michel
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 01.09.2002
Témata:
Absorptiometry, Photon
Adult
Biomarkers - blood
Body Composition - drug effects
Body Composition - physiology
Cadaver
Diet Records
Drug Administration Schedule
Energy Intake - drug effects
Energy Intake - physiology
Female
Humans
Immunosuppressive Agents - administration & dosage
Immunosuppressive Agents - therapeutic use
Kidney Transplantation
Longitudinal Studies
Male
Multivariate Analysis
Nutritional Status - drug effects
Nutritional Status - physiology
Prospective Studies
Sex Factors
Treatment Outcome
ISSN:1523-6838, 1523-6838
On-line přístup:Zjistit podrobnosti o přístupu
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Previous series have dealt with nutritional status after kidney transplantation. However, few studies have described the outcome of body composition after kidney transplantation. A total of 44 cadaver kidney transplant recipients (28 men and 16 women) were followed prospectively during the first post-transplant year. Biochemical nutritional markers, dietary records, anthropometric measurements, and body composition were assessed at kidney transplantation and 3, 6, and 12 months later. By the end of the first year, serum albumin level was not significantly different from initial values. Prealbumin and retinol binding protein decreased from 42.3 +/- 10.2 mg/dL to 30.4 +/- 6.3 mg/dL and from 1.96 +/- 0.61 g/dL to 0.65 +/- 0.2 g/dL (P < 0.0001). Separating patients by gender showed that dietary caloric and protein intake increased in women only. At the end of the follow-up period, mean weight change was +5.4 kg in women (P = 0.009) and -0.9 kg in men (not significant). Body composition analyses showed that in women total fat and lean masses increased (+2.1 kg, P = 0.05, and +2.4 kg, P = 0.006), whereas in men total fat mass decreased (-1.4 kg, P = 0.04), and total lean mass tended to increase (+0.5 kg, not significant). Percentage change in total bone mass was +1.4% in women (not significant) and -2.1% in men (P = 0.05). In multivariate analyses, an independent impact of female gender on weight gain was observed, although increased fat mass was related only to energy intake. Increased total lean mass was related to low steroid doses and the absence of acute rejection and delayed graft function. Bone loss was related to male gender and high steroid doses. Changes in body composition during the first year after kidney transplantation are modulated by gender, energy intake, steroid doses, the occurrence of acute rejection, and delayed graft function.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1523-6838
1523-6838
DOI:10.1053/ajkd.2002.34926