Cell competition during reprogramming gives rise to dominant clones

The ability to generate induced pluripotent stem cells from differentiated cell types has enabled researchers to engineer cell states. Although studies have identified molecular networks that reprogram cells to pluripotency, the cellular dynamics of these processes remain poorly understood. Here, by...

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Vydané v:	Science (American Association for the Advancement of Science) Ročník 364; číslo 6438
Hlavní autori:	Shakiba, Nika, Fahmy, Ahmed, Jayakumaran, Gowtham, McGibbon, Sophie, David, Laurent, Trcka, Daniel, Elbaz, Judith, Puri, Mira C, Nagy, Andras, van der Kooy, Derek, Goyal, Sidhartha, Wrana, Jeffrey L, Zandstra, Peter W
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 26.04.2019
Predmet:	Animals Cellular Reprogramming - genetics Cellular Reprogramming - physiology Cellular Reprogramming Techniques Clonal Evolution Clone Cells - cytology DNA - genetics Fibroblasts - cytology Induced Pluripotent Stem Cells - cytology Mice Models, Theoretical
ISSN:	1095-9203, 1095-9203
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