Genome-wide DNA methylation in neonates exposed to maternal depression, anxiety, or SSRI medication during pregnancy

Despite the high prevalence of depression, anxiety, and use of antidepressant medications during pregnancy, there is much uncertainty around the impact of high levels of distress or antidepressant medications on the developing fetus. These intrauterine exposures may lead to epigenetic alterations to...

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Vydáno v:	Epigenetics Ročník 9; číslo 7; s. 964 - 972
Hlavní autoři:	Non, Amy L, Binder, Alexandra M, Kubzansky, Laura D, Michels, Karin B
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Taylor & Francis 01.07.2014 Landes Bioscience
Témata:	antidepressants Antidepressive Agents - adverse effects anxiety Anxiety - complications Anxiety - drug therapy Case-Control Studies Cell Division Cohort Studies CpG Islands depression Depression - complications Depression - drug therapy DNA Methylation Female Fetal Blood - cytology Fetal Blood - metabolism Gene Expression Regulation Gene Ontology Genome, Human HumanMethylation450 BeadChip Humans Infant, Newborn Male Pregnancy Pregnancy Complications - drug therapy Prenatal Exposure Delayed Effects - etiology Prenatal Exposure Delayed Effects - genetics Prenatal Exposure Delayed Effects - metabolism prenatal exposures Protein Biosynthesis Research Paper Serotonin Uptake Inhibitors - adverse effects SSRI SSRI anxiety HumanMethylation450 BeadChip DNA methylation antidepressants depression prenatal exposures
ISSN:	1559-2294, 1559-2308, 1559-2308
On-line přístup:	Získat plný text
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