MDS clinical diagnostic criteria for Parkinson's disease

This document presents the Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's disease (PD). The Movement Disorder Society PD Criteria are intended for use in clinical research but also may be used to guide clinical diagnosis. The benchmark for these criteria is expert clinic...

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Vydané v:Movement disorders Ročník 30; číslo 12; s. 1591 - 1601
Hlavní autori: Postuma, Ronald B., Berg, Daniela, Stern, Matthew, Poewe, Werner, Olanow, C. Warren, Oertel, Wolfgang, Obeso, José, Marek, Kenneth, Litvan, Irene, Lang, Anthony E., Halliday, Glenda, Goetz, Christopher G., Gasser, Thomas, Dubois, Bruno, Chan, Piu, Bloem, Bastiaan R., Adler, Charles H., Deuschl, Günther
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States Blackwell Publishing Ltd 01.10.2015
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Predmet:
absolute exclusion criteria
clinical diagnostic criteria
Humans
motor parkinsonism
Movement disorders
Neuropsychological Tests
non-motor manifestations
Parkinson Disease - diagnosis
Parkinson Disease - physiopathology
Parkinson's disease
red flags
Reference Standards
Severity of Illness Index
Societies, Scientific - standards
supportive criteria
supportive criteria
motor parkinsonism
red flags
Parkinson's disease
non-motor manifestations
absolute exclusion criteria
clinical diagnostic criteria
ISSN:0885-3185, 1531-8257
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Shrnutí:This document presents the Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's disease (PD). The Movement Disorder Society PD Criteria are intended for use in clinical research but also may be used to guide clinical diagnosis. The benchmark for these criteria is expert clinical diagnosis; the criteria aim to systematize the diagnostic process, to make it reproducible across centers and applicable by clinicians with less expertise in PD diagnosis. Although motor abnormalities remain central, increasing recognition has been given to nonmotor manifestations; these are incorporated into both the current criteria and particularly into separate criteria for prodromal PD. Similar to previous criteria, the Movement Disorder Society PD Criteria retain motor parkinsonism as the core feature of the disease, defined as bradykinesia plus rest tremor or rigidity. Explicit instructions for defining these cardinal features are included. After documentation of parkinsonism, determination of PD as the cause of parkinsonism relies on three categories of diagnostic features: absolute exclusion criteria (which rule out PD), red flags (which must be counterbalanced by additional supportive criteria to allow diagnosis of PD), and supportive criteria (positive features that increase confidence of the PD diagnosis). Two levels of certainty are delineated: clinically established PD (maximizing specificity at the expense of reduced sensitivity) and probable PD (which balances sensitivity and specificity). The Movement Disorder Society criteria retain elements proven valuable in previous criteria and omit aspects that are no longer justified, thereby encapsulating diagnosis according to current knowledge. As understanding of PD expands, the Movement Disorder Society criteria will need continuous revision to accommodate these advances. © 2015 International Parkinson and Movement Disorder Society
Bibliografia:ark:/67375/WNG-G06LJMMJ-Z
istex:722A7C2940D2A97E9AB2919DD544F499056E8FD3
ArticleID:MDS26424
Contributed equally.
Full financial disclosures and author roles may be found in the online version of this article.
Nothing to report.
Relevant conflicts of interest/financial disclosures
Funding agencies
This study was supported by the work of the task force – i.e. meetings and tele‐conferences – were supported by the MDS.
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ISSN:0885-3185
1531-8257
DOI:10.1002/mds.26424