Evaluation of the physical properties and stability of two lipid drug delivery systems containing mefloquine

Stability data is used to determine the change the product has undergone over a certain time period at specific temperatures. In the present study, the physical stability characterized by size, pH and entrapment efficacy of mefloquine loaded liposomes and Pheroid™ vesicles were investigated. Size wa...

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Bibliographic Details
Published in:	International journal of pharmaceutics Vol. 409; no. 1; pp. 209 - 215
Main Authors:	Slabbert, C., Plessis, L.H. du, Kotzé, A.F.
Format:	Journal Article
Language:	English
Published:	Amsterdam Elsevier B.V 16.05.2011 Elsevier
Subjects:	Antimalarials - administration & dosage Antimalarials - chemistry Bioavailability Biological and medical sciences Colloids Data processing Drug delivery Drug delivery system Drug Delivery Systems Drug Stability Drug Storage drugs Fatty Acids - chemistry Flow Cytometry General pharmacology Hydrogen-Ion Concentration Lipid bilayers Liposome Liposomes Medical sciences Mefloquine Mefloquine - administration & dosage Mefloquine - chemistry Mefloquine hydrochloride Particle Size pH effects Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Pheroid™ Technology Spectrophotometry, Ultraviolet Stability Characterization Storage conditions Temperature Temperature effects Toxicity Vesicles EE PBS MQ Liposome ICH Stability Characterization Mefloquine hydrochloride Pheroid™ Technology RH FSC CLSM Drug delivery system WHO Antimalarial Evaluation Mefloquine Stability Pharmaceutical technology Lipids Drug carrier Physical properties Characterization Parasiticide Physicochemical properties
ISSN:	0378-5173, 1873-3476, 1873-3476
Online Access:	Get full text
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